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Dolutegravir 4-Desfluoro Impurity

CAS No.
1863916-87-3
Chemical Name:
Dolutegravir 4-Desfluoro Impurity
Synonyms
Dotiravir Impurity 2;Dotiravir Impurity 8;2-Fluoro Dolutegravir;4-Defluoro Dolutegravir;Dolutegravir Impurity 49;Dolutegravir Impurity 46;Doultegravir 2-F Impurity C;Dolutegravir 2-Fluoro Impurity;Dolutegravir 4-Desfluoro Impurity;Dolutegravir Impurity C (4-Defluoro Dolutegravir)
CBNumber:
CB94796146
Molecular Formula:
C20H20FN3O5
Molecular Weight:
401.39
MDL Number:
MOL File:
1863916-87-3.mol
Last updated:2022-12-21 16:56:50

Dolutegravir 4-Desfluoro Impurity Properties

Boiling point 671.6±55.0 °C(Predicted)
Density 1.49±0.1 g/cm3(Predicted)
pka 4.50±1.00(Predicted)
FDA UNII 29LH9LED64

Dolutegravir 4-Desfluoro Impurity price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D228820 4-DefluoroDolutegravir 1863916-87-3 2.5mg $445 2021-12-16 Buy
Product number Packaging Price Buy
D228820 2.5mg $445 Buy

Dolutegravir 4-Desfluoro Impurity Chemical Properties,Uses,Production

Uses

4-Defluro Dolutegravir is an impurity of Dolutegravir (D528800), a second generation HIV-1 integrase strand transfer inhibitor. Dolutegravir is currently in Phase III clinical trials for the treatment of HIV infection. Dolutegravir has been shown to potently inhibit HIV replication in cells such as peripheral blood mononuclear cells (PBMCs), MT-4 cells and CIP4 cells infected with a self-inactivating PHIV lentiviral vector.

Dolutegravir 4-Desfluoro Impurity Preparation Products And Raw materials

Raw materials

Preparation Products

Dolutegravir 4-Desfluoro Impurity Suppliers

Global( 32)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14332 58
CR Corporation Limited
+8613062833949 fred.wen@crcorporation.cn China 8647 58
sgtlifesciences pvt ltd
+8617013299288 dj@sgtlifesciences.com China 12373 58
China National Standard Pharmaceutical Corporation Limited
+8615391658522 overseasales@yongstandards.com China 11922 58
ShenZhen H&D Pharmaceutical Technology Co., LTD
+8618627948422 sale@hdimpurity.com China 3389 58
Beijing Comparison Pharmaceutical Technology Co., Ltd 010-010-52878169 15801002657 sales@bjcomparison.com China 4948 58
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396 sales@chem-strong.com China 18043 56
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9906 50
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@qq.com China 8376 55
Shanghai CR Corporation Limited 021-80270511; 4006653949 fred.wen@crcorporation.cn China 10044 58
Dolutegravir impurity 1/4-Defluoro Dolutegravir/(4R,12aS)-N-(2-Fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide (4R,12aS)-N-(2-fluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide 4-Defluoro Dolutegravir 2H-Pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, N-[(2-fluorophenyl)methyl]-3,4,6,8,12,12a-hexahydro-7-hydroxy-4-methyl-6,8-dioxo-, (4R,12aS)- Doultegravir 2-F Impurity C Dolutegravir Impurity C (4-Defluoro Dolutegravir) Dolutegravir Impurity 46 Dolutegravir Impurity 49 2-Fluoro Dolutegravir Dolutegravir 2-Fluoro Impurity Dolutegravir 4-Desfluoro Impurity Dotiravir Impurity 2 Dotiravir Impurity 8 1863916-87-3