BAY-826 (BAY826)
- CAS No.
- 1448316-08-2
- Chemical Name:
- BAY-826 (BAY826)
- Synonyms
- BAY-826 (BAY826);[3-Cyano-5-[[[2,4-dimethyl-5-[6-(3-pyridinyl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl]amino]carbonyl]phenyl]pentafluorosulfur;Sulfur, [3-cyano-5-[[[2,4-dimethyl-5-[6-(3-pyridinyl)-1H-imidazo[1,2-b]pyrazol-1-yl]phenyl]amino]carbonyl]phenyl]pentafluoro-, (OC-6-21)-
- CBNumber:
- CB64844529
- Molecular Formula:
- C26H19F5N6OS
- Molecular Weight:
- 558.53
- MDL Number:
- MFCD31657322
- MOL File:
- 1448316-08-2.mol
BAY-826 (BAY826) Chemical Properties,Uses,Production
Description
BAY-826 is a highly potent, orally available TIE-2-inhibitor which improves tumor control in syngeneic mouse glioma models.
Definition
ChEBI: BAY-826 is a secondary carboxamide resulting from the formal condensation of the carboxy group of 3-cyano-5-(pentafluoro-lambda(6)-sulfanyl)benzoic acid with the amino group of 2,4-dimethyl-5-[6-(pyridin-3-yl)-1H-imidazo[1,2-b]pyrazol-1-yl]aniline. It is a potent TIE-2 inhibitor (Kd = 1.6 nM) which displays in vivo efficacy in some murine glioma models. It has a role as an EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor and an antineoplastic agent. It is a member of pyridines, an imidazopyrazole, a member of benzamides, a secondary carboxamide, a nitrile, an organofluorine compound and an organosulfur compound.
storage
Store at -20°C
BAY-826 (BAY826) Preparation Products And Raw materials
Raw materials
Preparation Products
BAY-826 (BAY826) Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
Beijing Solarbio Science & Tecnology Co., Ltd. | 010-50973130 4009686088 | 3193328036@qq.com | China | 29786 | 68 |
InvivoChem | 13549236410 | sales@invivochem.cn | China | 6755 | 58 |
Nantong QuanYi Biotechnology Co., Ltd | 0513-66337626 18051384581 | sales@chemhifuture.com | China | 4607 | 58 |
TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 28091 | 58 |
Nanjing Shizhou Biology Technology Co.,Ltd | 025-85560043 15850508050 | cindy.huang@synzest.com | China | 12007 | 58 |