4,7-Dichloroquinoline
- CAS No.
- 86-98-6
- Chemical Name:
- 4,7-Dichloroquinoline
- Synonyms
- COPPER SEBACATE;Sulfate Impurity;4,7-dichloro-quinolin;tl1473;TL 1473;4, 7-dichloroquine;7-Dichloroquinoline;Chloroquine USP RC A;Amodiaquine Impurity;4,7-DICHLOROQUINOLINE
- CBNumber:
- CB6490818
- Molecular Formula:
- C9H5Cl2N
- Molecular Weight:
- 198.05
- MDL Number:
- MFCD00006774
- MOL File:
- 86-98-6.mol
- MSDS File:
- SDS
| Melting point | 81-83 °C (lit.) |
|---|---|
| Boiling point | 298.4 °F (148°C) |
| Density | 1.4178 (rough estimate) |
| vapor pressure | 0.103Pa at 25℃ |
| refractive index | 1.6300 (estimate) |
| Flash point | 164 °C |
| storage temp. | 2-30°C |
| solubility | chloroform: soluble50mg/mL, clear, colorless to greenish-yellow |
| pka | 1.99±0.27(Predicted) |
| form | Powder |
| color | White to pale brown |
| PH | 3.86 (24.9°C) |
| biological source | synthetic |
| Water Solubility | insoluble |
| BRN | 125359 |
| InChIKey | HXEWMTXDBOQQKO-UHFFFAOYSA-N |
| LogP | 3.193 at 25℃ |
| CAS DataBase Reference | 86-98-6(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | Z61O2HEQ2J |
| NIST Chemistry Reference | Quinoline, 4,7-dichloro-(86-98-6) |
| EPA Substance Registry System | 4,7-Dichloroquinoline (86-98-6) |
| UNSPSC Code | 41116107 |
| NACRES | NA.24 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS09 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H317-H319-H411 | |||||||||
| Precautionary statements | P261-P264-P273-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36-22 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | VB4200000 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | Yes | |||||||||
| HS Code | 29334910 | |||||||||
| NFPA 704 |
|
4,7-Dichloroquinoline price More Price(35)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | PHR2438 | Chloroquine Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material | 86-98-6 | 50MG | $668 | 2024-03-01 | Buy |
| Sigma-Aldrich | 141437 | 4,7-Dichloroquinoline ≥99% | 86-98-6 | 25g | $117 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1118328 | Chloroquine Related Compound A United States Pharmacopeia (USP) Reference Standard | 86-98-6 | 15MG | $1210 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1118328 | Chloroquine Related Compound A United States Pharmacopeia (USP) Reference Standard | 86-98-6 | 25mg | $1220 | 2022-05-15 | Buy |
| TCI Chemical | D1100 | 4,7-Dichloroquinoline >98.0%(GC) | 86-98-6 | 25g | $42 | 2024-03-01 | Buy |
4,7-Dichloroquinoline Chemical Properties,Uses,Production
Chemical Properties
white to light yellow crystal powder
Uses
4,7-Dichloroquinoline is used as a drug chloroquine phosphate intermediate. It was used in the synthesis of piperaquine. and as starting reagent in the synthesis of {3-amino-5-[(7-chloro-4-quinolyl)amino]phenyl}methanol.
Uses
4,7-Dichloroquinoline is used in the synthesis of hybrid aminoquinoline-triazine derivatives that show anti-microbial activity. In addition, it is used in the synthesis of novel oxazolidinones as anti -microbial agents showing efficacy against common bacterial strains. Chloroquinoline impurity.
General Description
Chloroquine Related Compound A is an impurity of chloroquine, which is a 9-aminoquinoline drug that effectively inhibits viral infections in humans.
Flammability and Explosibility
Not classified
Synthesis
4,7-Dichloroquinoline is obtained by chlorination of 7-chloro-4-hydroxyquinoline.
Purification Methods
Crystallise the dichloroquinoline from MeOH or 95% EtOH. [Beilstein 20/7 V 316.]
4,7-Dichloroquinoline Preparation Products And Raw materials
Raw materials
Preparation Products
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| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | +86-（0）57185586718 +86-13336195806 | sales@capot.com | China | 29730 | 60 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 22854 | 58 |
| Hebei Chuanghai Biotechnology Co., Ltd | +8615531157085 | abby@chuanghaibio.com | China | 8808 | 58 |
| Hebei Mujin Biotechnology Co.,Ltd | +86 13288715578 +8613288715578 | sales@hbmojin.com | China | 12809 | 58 |
| Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5868 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2472 | 58 |
| Anhui Ruihan Technology Co., Ltd | +8617756083858 | daisy@anhuiruihan.com | China | 973 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21628 | 55 |
| Fluoropharm Co., Ltd. | +86-0571-85586753 +86-13336034509 | sales@fluoropharm.com | China | 1445 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29858 | 58 |
View Lastest Price from 4,7-Dichloroquinoline manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2025-04-25 | 4,7-Dichloroquinoline
86-98-6
|
US $0.00 / kg | 1kg | 99% GC | 500kgs | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2025-04-25 | 4,7-Dichloroquinoline
86-98-6
|
US $0.00 / Kg/Drum | 1g | 99% | 20mt | Jinan Finer Chemical Co., Ltd | |
 |
2025-04-23 | 4,7-Dichloroquinoline
86-98-6
|
US $10.00 / KG | 1KG | 99% | 100 mt | Hebei Chuanghai Biotechnology Co., Ltd |
-
- 4,7-Dichloroquinoline
86-98-6
- US $0.00 / kg
- 99% GC
- WUHAN FORTUNA CHEMICAL CO., LTD
-
- 4,7-Dichloroquinoline
86-98-6
- US $0.00 / Kg/Drum
- 99%
- Jinan Finer Chemical Co., Ltd
-
- 4,7-Dichloroquinoline
86-98-6
- US $10.00 / KG
- 99%
- Hebei Chuanghai Biotechnology Co., Ltd
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