ChemicalBook >> CAS DataBase List >>CFI-401980
CFI-401980
- CAS No.
- 1610676-27-1
- Chemical Name:
- CFI-401980
- Synonyms
- CFI-401980;CFI401980,CFI 401980;Benzamide, N-cyclopropyl-2-methyl-4-[2-phenoxy-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]pyrazolo[1,5-a]-1,3,5-triazin-8-yl]-
- CBNumber:
- CB64919751
- Molecular Formula:
- C28H30N6O3
- Molecular Weight:
- 498.58
- MDL Number:
- MOL File:
- 1610676-27-1.mol
Last updated:2024-10-23 13:36:13
CFI-401980 Chemical Properties,Uses,Production
Description
CFI-401980 a potent and selective, novel class of TTK inhibitor (TKK Ki = 0.8 nM; HCT116 GI50 = 13 nM, rat PK: oral BA =97%). CFI-401980 demonstrate a strong anti-proliferative activity in a panel of human cancer cell lines (HCT116 GI50 < 15 nM) and good rodent pharmacokinetics (oral %F 97 %). TTK/Mps1 is a key kinase controlling progression of cell division via participation in the mitotic spindle assembly checkpoint and is overexpressed in a number of human cancers.
CFI-401980 Preparation Products And Raw materials
Raw materials
Preparation Products
CFI-401980 Suppliers
Global( 3)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38632 | 58 | |
| TargetMol Chemicals Inc. | +8613564774135 | zijue.cai@tsbiochem.com | United States | 19885 | 58 |
| TargetMol Chemicals Inc. | 15002134094 | marketing@targetmol.cn | China | 19707 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
| TargetMol Chemicals Inc. | 58 |
View Lastest Price from CFI-401980 manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-24 | CFI-401980
1610676-27-1
|
US $3700.00-2120.00 / mg | 10g | TargetMol Chemicals Inc. |
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- CFI-401980
1610676-27-1
- US $3700.00-2120.00 / mg
- TargetMol Chemicals Inc.
CFI-401980
CFI401980,CFI 401980
Benzamide, N-cyclopropyl-2-methyl-4-[2-phenoxy-4-[[(tetrahydro-2H-pyran-4-yl)methyl]amino]pyrazolo[1,5-a]-1,3,5-triazin-8-yl]-
1610676-27-1