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Temocaprilat

CAS No.
110221-53-9
Chemical Name:
Temocaprilat
Synonyms
Temocaprilate;RS-5139;Temocaprilat;Temocapril Diacid;[3H]-Temocaprilat;Temocapril Impurity 1;TEMOCAPRILAT(FORR&DONLY);[[[2S,6R]-6-[[(S)-1-Carboxy-3-phenylpropyl]amino]hexahydro-5-oxo-2-(2-thienyl)-1,4-thiazepin]-4-yl]acetic acid;(2S,6R)-6-[[(1S)-1-Carboxy-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-1,4-thiazepine-4(5H)-acetic Acid;1,4-Thiazepine-4(5H)-acetic acid, 6-[[(1S)-1-carboxy-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-, (2S,6R)-
CBNumber:
CB6501004
Molecular Formula:
C21H24N2O5S2
Molecular Weight:
448.56
MDL Number:
MFCD00871951
MOL File:
110221-53-9.mol
MSDS File:
SDS
Last updated:2024-11-06 18:33:45

Temocaprilat Properties

Melting point >2300C (dec)
alpha 25D +63.4° (c = 1 in DMF)
Boiling point 743.6±60.0 °C(Predicted)
Density 1.41±0.1 g/cm3(Predicted)
storage temp. Sealed in dry,2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 2.09±0.10(Predicted)
color White to Off-White
FDA UNII 2D6A12Q12R

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H317-H319
Precautionary statements  P280-P305+P351+P338

Temocaprilat price More Price(14)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 22169 Temocaprilat 110221-53-9 500μg $121 2024-03-01 Buy
Cayman Chemical 22169 Temocaprilat 110221-53-9 1mg $218 2024-03-01 Buy
Cayman Chemical 22169 Temocaprilat 110221-53-9 5mg $722 2024-03-01 Buy
TRC T017305 Temocaprilat 110221-53-9 1g $1015 2021-12-16 Buy
AK Scientific O437 Temocaprilat 110221-53-9 1g $1366 2021-12-16 Buy
Product number Packaging Price Buy
22169 500μg $121 Buy
22169 1mg $218 Buy
22169 5mg $722 Buy
T017305 1g $1015 Buy
O437 1g $1366 Buy

Temocaprilat Chemical Properties,Uses,Production

Description

Temocaprilat is an inhibitor of angiotensin-converting enzyme (ACE; IC50 = 3.6 nM for rabbit lung ACE). It inhibits contraction of isolated rat aorta induced by angiotensin I with an IC50 value of 7.6 nM. Temocaprilat (1-30 μg/kg, i.v.) inhibits angiotensin I-induced pressor responses in anesthetized rats in a dose-dependent manner.

Chemical Properties

White to Off-White Solid

Uses

Antihypertensive.

Definition

ChEBI: Temocaprilat is a non-proteinogenic alpha-amino acid.

Temocaprilat Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 53)Suppliers
Supplier Tel Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29791 60
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 49374 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32072 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 23025 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739 info@dycnchem.com China 52849 58
PT CHEM GROUP LIMITED
peter68@ptchemgroup.com China 35425 58
GIHI CHEMICALS CO.,LIMITED
+8618058761490 info@gihichemicals.com China 49979 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
Shanghai Longsheng chemical Co.,Ltd. 021-58099652-8005 13585536065 bin.wu@shlschem.com China 9809 59
Chemsky(shanghai)International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32321 50

View Lastest Price from Temocaprilat manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Temocaprilat pictures 2024-11-06 Temocaprilat
110221-53-9
US $198.00-418.00 / mg 96.88% 10g TargetMol Chemicals Inc.
Temocaprilat pictures 2022-05-17 Temocaprilat
110221-53-9
US $1.10 / g 1g 99.9% Min 100 Tons Dideu Industries Group Limited
  • Temocaprilat pictures
  • Temocaprilat
    110221-53-9
  • US $198.00-418.00 / mg
  • 96.88%
  • TargetMol Chemicals Inc.
  • Temocaprilat pictures
  • Temocaprilat
    110221-53-9
  • US $1.10 / g
  • 99.9% Min
  • Dideu Industries Group Limited
RS-5139 TEMOCAPRILAT(FORR&DONLY) (+)-[(2S,6R)-6-[[(S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-5-oxo-2-(2-thienyl)perhydro-1,4-thiazepin-4-yl]acetic acid [[[2S,6R]-6-[[(S)-1-Carboxy-3-phenylpropyl]amino]hexahydro-5-oxo-2-(2-thienyl)-1,4-thiazepin]-4-yl]acetic acid (2S,6R)-6-[[(1S)-1-Carboxy-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-1,4-thiazepine-4(5H)-acetic Acid Temocapril Diacid Temocaprilat [3H]-Temocaprilat 1,4-Thiazepine-4(5H)-acetic acid, 6-[[(1S)-1-carboxy-3-phenylpropyl]amino]tetrahydro-5-oxo-2-(2-thienyl)-, (2S,6R)- Temocaprilate Temocapril Impurity 1 110221-53-9 C21H24N2O5S2 Intermediates & Fine Chemicals Pharmaceuticals