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GGTI 2133

CAS No.
191102-79-1
Chemical Name:
GGTI 2133
Synonyms
L-Leucine, N-[4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthalenyl)benzoyl]-
CBNumber:
CB6503543
Molecular Formula:
C27H28N4O3
Molecular Weight:
456.54
MDL Number:
MFCD02683592
MOL File:
191102-79-1.mol
Last updated:2023-05-04 17:34:35

GGTI 2133 Properties

Melting point 103-118.5 °C
storage temp. −20°C
solubility DMSO: 25 mg/mL
form solid
color white

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H319-H335-H315
Precautionary statements  P264-P280-P305+P351+P338-P337+P313P-P264-P280-P302+P352-P321-P332+P313-P362
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
WGK Germany  3

GGTI 2133 price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 23418 GGTI 2133 ≥98% 191102-79-1 500μg $95 2021-12-16 Buy
Cayman Chemical 23418 GGTI 2133 ≥98% 191102-79-1 1mg $181 2021-12-16 Buy
TRC G368895 GGTI-2133 191102-79-1 5mg $550 2021-12-16 Buy
TRC G368895 GGTI-2133 191102-79-1 25mg $1655 2021-12-16 Buy
American Custom Chemicals Corporation INB0001023 GGTI-2133 95.00% 191102-79-1 1MG $683.99 2021-12-16 Buy
Product number Packaging Price Buy
23418 500μg $95 Buy
23418 1mg $181 Buy
G368895 5mg $550 Buy
G368895 25mg $1655 Buy
INB0001023 1MG $683.99 Buy

GGTI 2133 Chemical Properties,Uses,Production

Uses

GGTI-2133 i an inhibitors of protein geranylgeranyltransferase-I. Increases prelamin A accumulation by inhibiting ZMPSTE24 protein in human fibroblast. GGTI-2133 inhibited proliferation and migration via involvement of RhoA and RalB proteins in human oral squamous cell carcinoma cell.

Definition

ChEBI: GGTI-2133 free base is an N-acyl-L-amino acid obtained by condensation of the carboxy group of 4-{[(imidazol-4-yl)methyl]amino}-2-(naphthalen-1-yl)benzoic acid with the amino group of L-leucine. An inhibitor of geranylgeranyltransferase type I. It has a role as an EC 2.5.1.59 (protein geranylgeranyltransferase type I) inhibitor. It is a L-leucine derivative, a N-acyl-L-amino acid, a member of naphthalenes, a biaryl, a member of imidazoles, a member of benzamides, a substituted aniline and a secondary amino compound. It is a conjugate base of a GGTI-2133 free base(1+).

GGTI 2133 Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 94658 76
Shanghai TaoSu Biochemical Technology Co., Ltd. 021-33632979 info@tsbiochem.com China 8072 58
Shenzhen Polymeri Biochemical Technology Co., Ltd. +86-400-002-6226 13028896684 sales@rrkchem.com China 56077 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 23963 58
Suzhou Zhixin Biotechnology Co., Ltd. 0512-65118909 15162312715 sales@szzxbio.com China 3014 58
L-Leucine, N-[4-[(1H-imidazol-5-ylmethyl)amino]-2-(1-naphthalenyl)benzoyl]- 191102-79-1 Amino Acids & Derivatives, Chiral Reagents, Heterocycles, Inhibitors