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(S)-5-Hydroxymethyldihydrofuran-2-one

(S)-5-Hydroxymethyldihydrofuran-2-one Structure
(S)-5-Hydroxymethyldihydrofuran-2-one structure
CAS No.
32780-06-6
Chemical Name:
(S)-5-Hydroxymethyldihydrofuran-2-one
Synonyms
5-(Hydroxymethyl)dihydro-2(3H)-furanone;(S)-(+)-γ-Hydroxymethyl-γ(S)-Gamma-Hydroxymethyl-Gamma;(S)-4-HYDROXYMETHYL BUTYROLACTONE;(5S)-5-(hydroxyMethyl)oxolan-2-one;(s)-γ-hydroxymethyl-γ-butyrolactone;(S)-5-Hydroxymethyldihydrofuran-2-on;(S)-(+)-G-HYDROXYMETHYL-G-BUTYROLACTONE;(S)-5-HYDROXYMETHYL-DIHYDRO-FURAN-2-ONE
CBNumber:
CB6702069
Molecular Formula:
C5H8O3
Molecular Weight:
116.12
MDL Number:
MFCD00066224
MOL File:
32780-06-6.mol
MSDS File:
SDS
Last updated:2024-08-01 17:24:36
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(S)-5-Hydroxymethyldihydrofuran-2-one Properties

Melting point 72-74 °C
Boiling point 110-115 °C/0.2 mmHg (lit.)
alpha 56 º (c=3 in chloroform)
Density 1.237 g/mL at 25 °C (lit.)
refractive index n20/D 1.471(lit.)
Flash point >230 °F
storage temp. 2-8°C
pka 14.12±0.10(Predicted)
form clear liquid
color Colorless to Almost colorless
optical activity [α]20/D +56°, c = 3 in chloroform
BRN 1680284
CAS DataBase Reference 32780-06-6(CAS DataBase Reference)
NIST Chemistry Reference (S)-(+)-2',3'-dideoxyribonolactone(32780-06-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319
Precautionary statements  P264-P280-P302+P352-P337+P313-P305+P351+P338-P362+P364-P332+P313
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  23-24/25-37/39-26
WGK Germany  3
HS Code  29322090
NFPA 704
1
0 0

(S)-5-Hydroxymethyldihydrofuran-2-one price More Price(26)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 348902 (S)-(+)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone 95% 32780-06-6 1g $226 2023-06-20 Buy
TCI Chemical H0958 (S)-(+)-γ-Hydroxymethyl-γ-butyrolactone >94.0%(GC) 32780-06-6 1g $114 2024-03-01 Buy
TCI Chemical H0958 (S)-(+)-γ-Hydroxymethyl-γ-butyrolactone >94.0%(GC) 32780-06-6 5g $504 2024-03-01 Buy
TRC H973063 (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one 32780-06-6 1g $65 2021-12-16 Buy
Matrix Scientific 119181 (S)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one 95+% 32780-06-6 1g $72 2021-12-16 Buy
Product number Packaging Price Buy
348902 1g $226 Buy
H0958 1g $114 Buy
H0958 5g $504 Buy
H973063 1g $65 Buy
119181 1g $72 Buy

(S)-5-Hydroxymethyldihydrofuran-2-one Chemical Properties,Uses,Production

Chemical Properties

Colorless to light yellow liqui

Uses

(S)-(+)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone can be used as a chiral synthon to synthesize:

  • Potent nucleoside, acetylcholine, and (+)-muricatacin analogs.
  • Mevinic acids, which are LDL cholesterol-lowering agents.
  • Adenine based anti-HIV agent named β-F-ddA.

General Description

Dihydro-5-(hydroxymethyl)-2(3H)-furanone is a chiral building block widely used in the synthesis of many natural products and few biologically significant compounds like anti-HIV dideoxynucleosides. It is also used in the synthesis of optically active ligands.

(S)-5-Hydroxymethyldihydrofuran-2-one synthesis

67-56-1
5336-08-3
32780-06-6
196080-40-7
Synthesis of (S)-5-Hydroxymethyldihydrofuran-2-one from Methanol and D(+)-Ribonic acid gamma-lactone

(S)-5-Hydroxymethyldihydrofuran-2-one Preparation Products And Raw materials

Raw materials

Borane-methyl sulfide complex L-Glutamic acid Sodium nitrite Tetrahydrofuran Benzene
Ethyl acetate Hydrochloric acid Methanol PETROLEUM ETHER Pentanoic acid, 4,5-dihydroxy-, methyl ester, (4S)-
D-threo-Pentonic acid, 2-deoxy-, γ-lactone (5S)-5-(trityloxymethyl)-5H-furan-2-one 2-Oxiranepropanoic acid, methyl ester, (2R)- 2-Oxiranepropanoic acid, methyl ester (S)-(+)-GAMMA-(TRITYLOXYMETHYL)-GAMMA-BUTYROLACTONE
(S)-(-)HYDROXYMETHYL-3(2H)-FURANONE (1S,5R)-6,8-dioxabicyclo[3.2.1]octan-4-one

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Preparation Products

(S)-5-Hydroxymethyldihydrofuran-2-one Suppliers

Global( 166)Suppliers
Supplier Tel Email Country ProdList Advantage
Shaanxi Dideu Medichem Co. Ltd 		+86-029-81138252 +86-18789408387 1057@dideu.com China 3958 58
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 18777 58
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32957 60
career henan chemical co 		+86-0371-86658258 +8613203830695 sales@coreychem.com China 29882 58
Shenzhen Nexconn Pharmatechs Ltd 		+86-755-89396905 +86-15013857715 admin@nexconn.com China 10310 58
Accela ChemBio Inc. 		+1-858-6993322 info@accelachem.com United States 17322 58
Chongqing Chemdad Co., Ltd 		+86-023-6139-8061 +86-86-13650506873 sales@chemdad.com China 39894 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		+8613580539051 joe@yuhengpharm.com CHINA 21142 58
SIMAGCHEM CORP 		+86-13806087780 sale@simagchem.com China 17365 58
Supplier Advantage
Shaanxi Dideu Medichem Co. Ltd 		58
Shanghai Daken Advanced Materials Co.,Ltd 		58
ATK CHEMICAL COMPANY LIMITED 		60
career henan chemical co 		58
Shenzhen Nexconn Pharmatechs Ltd 		58
Accela ChemBio Inc. 		58
Chongqing Chemdad Co., Ltd 		58
Alchem Pharmtech,Inc. 		58
Guangzhou Yuheng Pharmaceutical Technology Co., Ltd 		58
SIMAGCHEM CORP 		58

View Lastest Price from (S)-5-Hydroxymethyldihydrofuran-2-one manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
(S)-5-Hydroxymethyldihydrofuran-2-one pictures 2024-08-02 (S)-5-Hydroxymethyldihydrofuran-2-one
32780-06-6
 US $1.00 / KG 1KG 99% 20T Shaanxi Dideu Medichem Co. Ltd
(S)-5-Hydroxymethyldihydrofuran-2-one pictures 2019-07-06 (S)-5-Hydroxymethyldihydrofuran-2-one
32780-06-6
 US $1.00 / KG 1KG 98% 150KG Career Henan Chemical Co

(S)-5-Hydroxymethyldihydrofuran-2-one Spectrum

(S)-5-Hydroxymethyldihydrofuran-2-one(32780-06-6)1HNMR(S)-5-Hydroxymethyldihydrofuran-2-one(32780-06-6)IR

32780-06-6((S)-5-Hydroxymethyldihydrofuran-2-one)Related Search:

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(S)-(+)-gamma-Hydroxymethyl-gamma-butyrolactone,97% (S)-Gamma-Hydroxymethyl-Gamma (S)-(+)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone ,97% (5S)-5-(HYDROXYMETHYL)-3,4,5-TRIHYDROFURAN-2-ONE (5S)-(+)-5-(Hydroxymethyl)dihydrofuran-2(3H)-one (S)-(+)-4,5-Dihydro-5-hydroxymethyl-2(3H)-furanone (S)-(+)-5-Hydroxymethyltetrahydro-2-furanone 5-Oxo-tetrahydro-furan-2-carboxylic acid ethyl ester (5S)-5-(hydroxyMethyl)oxolan-2-one 2(3H)-Furanone,dihydro-5-(hydroxyMethyl)-, (5S)- (S)-(+)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone 95% (S)-(+)-&gamma -Hydroxymethyl-&gamma (S)-(+)-DIHYDRO-5-(HYDROXYMETHYL)-2(3H)-FURANONE (S)-(+)-DIHYDRO-5-(HYDROXYMETHYL)FURANONE (S)-(+)-GAMMA-HYDROXYMETHYL-GAMMA-BUTYROLACTON (S)-(+)-GAMMA-HYDROXYMETHYL-GAMMA-BUTYROLACTONE (S)-GAMMA-HYDROXYMETHYL-GAMMA-BUTYROLACTONE (S)-(+)-G-HYDROXYMETHYL-G-BUTYROLACTONE (S)-(+)-4,5-DIHYDRO-5-HYDROXYMETHYL-2(3H)-FURANONE (S)-4,5-DIHYDRO-5-HYDROXYMETHYL-2(3H)-FURANONE DIHYDRO-5-(HYDROXYMETHYL)-2(3H)-FURANONE (S-) 2(3H)-FURANONE, DIHYDRO-5-(HYDROXYMETHYL)-,(S) (S)-4-HYDROXYMETHYL BUTYROLACTONE (S)-5-HYDROXYMETHYL-2-OXOTETRAHYDROFURAN (S)-5-HYDROXYMETHYL-DIHYDRO-FURAN-2-ONE (S)-(+)-5-HYDROXYMETHYL-GAMMA-BUTYROLACTONE (S)-(+)-5-HYDROXYMETHYLTETRAHYDRO-2-FURANONE (S)-γ-Hydroxymethyl-γ-butyrolactone, (S)-4,5-Dihydro-5-hydroxymethyl-2(3H)-furanone, (S)-5-Hydroxymethyl-2-oxotetrahydrofuran (S)-4,5-Dihydro-5-hydroxymethyl-2(3H)-furanone, (S)-5-Hydroxymethyl-2-oxotetrahydrofuran (S)-(+)-DIHYDRO-5-(HYDROXYMETHYL)-2(3H)- FURANONE, 95% (98% EE/GLC) (S)-GAMMA-HYDROXYMETHYL-GAMMA-BUTYRO- & (s)-γ-hydroxymethyl-γ-butyrolactone (S)-(+)-5-HYDROXYMETHYL-GAMMA-BUTYROLACTONE 98% (5S)-5-(hydroxymethyl)-2-oxo-tetrahydrofuran (S)-5-Hydroxymethyldihydrofuran-2-on (S)-(+)-γ-Hydroxymethyl-γ-butyrolactone> 5-(Hydroxymethyl)dihydro-2(3H)-furanone (5S)-5-(Hydroxymethyl)dihydro-2(3H)-furanone 32780-06-6 Asymmetric Synthesis Chiral Building Blocks Heterocyclic Building Blocks Furans chiral Chiral Reagent