ANTI-P21
- CAS No.
- Chemical Name:
- ANTI-P21
- Synonyms
- ANTI-P21;ANTI-SDI1;ANTI-WAF1;ANTI-PIC1;ANTI-CIP1;Anti-SMT3C;Anti-SMT3H3;ANTI-P21WAF1;ANTI-P21(F-5);ANTI-P21(187)
- CBNumber:
- CB6782694
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00802813
- MOL File:
- Mol file
ANTI-P21 Chemical Properties,Uses,Production
Uses
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Western Blotting (1 paper)
General Description
Monoclonal Anti-p21WAF1/Cip1 (mouse IgG2b isotype) is derived from the CP74 hybridoma produced by the fusion of mouse myeloma cells and splenocytes from a BALB/c mouse immunized with recombinant human p21WAF1/Cip1. p21WAF1/Cip1 is 21 kDa and designated as Cip1, WAF1, Sdi1, Pic1, CAP20.
Biochem/physiol Actions
Regulation of cell cycle progression in eukaryotic cells depends on the expression of proteins called cyclins. These proteins form complexes with several different cyclin dependent kinases (CDKs). The catalytic activity of cyclin dependent kinases (CDK) is regulated by two general mechanisms: protein phosphorylation and association with regulatory subunits, which include the cyclins and the CDK inhibitors (CKIs). These inhibit all kinases involved in the G1/S transition. The the p16INK4a family, which includes p15INK4b, p16INK4a, p18INK4c and p19INK4d, inhibits Cdk4 and Cdk6 specifically.
ANTI-P21 Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-P21 Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |