ChemicalBook >> CAS DataBase List >>ORPHENADRINE HYDROCHLORIDE
ORPHENADRINE HYDROCHLORIDE
- CAS No.
- 341-69-5
- Chemical Name:
- ORPHENADRINE HYDROCHLORIDE
- Synonyms
- BF 5930;BG 5930;BS 5930;Mebedrol;Mephenamin;Brocasipal;Mephenamine;Brocadisipal;mephenaminforte;Mephenamin forte
- CBNumber:
- CB6782740
- Molecular Formula:
- C18H24ClNO
- Molecular Weight:
- 305.84
- MDL Number:
- MFCD00012480
- MOL File:
- 341-69-5.mol
- MSDS File:
- SDS
Last updated:2024-11-01 13:17:44
| Melting point | 159.0 to 164.0 °C |
|---|---|
| Boiling point | -195 °C |
| Density | 0.295 g/cm3 |
| storage temp. | 2-8°C |
| solubility | Freely soluble in water and in ethanol (96 per cent). |
| color | Crystals |
| BRN | 3745818 |
| Stability | Stable. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 341-69-5(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | UBY910DUXH |
| EPA Substance Registry System | Orphenadrine hydrochloride (341-69-5) |
ORPHENADRINE HYDROCHLORIDE price More Price(10)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | Y0000100 | Orphenadrine hydrochloride European Pharmacopoeia (EP) Reference Standard | 341-69-5 | y0000100 | $150 | 2024-03-01 | Buy |
| Sigma-Aldrich | 75517 | Orphenadrine hydrochloride 99% | 341-69-5 | 5g | $64.2 | 2024-03-01 | Buy |
| Cayman Chemical | 26391 | Orphenadrine (hydrochloride) | 341-69-5 | 10mg | $49 | 2024-03-01 | Buy |
| Cayman Chemical | 26391 | Orphenadrine (hydrochloride) | 341-69-5 | 25mg | $115 | 2024-03-01 | Buy |
| Sigma-Aldrich | Y0001181 | Orphenadrine for peak identification European Pharmacopoeia (EP) Reference Standard | 341-69-5 | y0001181 | $203 | 2024-03-01 | Buy |
ORPHENADRINE HYDROCHLORIDE Chemical Properties,Uses,Production
Chemical Properties
White or almost white, crystalline powder.
Uses
Antihistaminic;H1 antogonist
Definition
ChEBI: A hydrochloride comprising equimolar amounts of ophenadrine and hydrogen chloride.
General Description
Odorless white or almost white crystalline powder. pH (aqueous solution) about 5.5. Bitter numbing taste.
Air & Water Reactions
May be sensitive to prolonged exposure to light and air. Water soluble.
Reactivity Profile
ORPHENADRINE HYDROCHLORIDE is incompatible with strong oxidizers.
Fire Hazard
Flash point data for ORPHENADRINE HYDROCHLORIDE are not available; however, ORPHENADRINE HYDROCHLORIDE is probably combustible.
Biochem/physiol Actions
Muscarinic receptor antagonist; H1 histamine receptor antagonist; muscle relaxant. Orphenadrine has also been reported to inhibit the noradrenergic transporter and to block the NMDA receptor ion channel.
Clinical Use
Anti-muscarinic:
Parkinsonism
Drug induced extra-pyramidal symptoms
Safety Profile
Poison by ingestion, intravenous, intraperitoneal, and subcutaneous routes. Human systemic effects: mydriasis @updlaryd ilation), hallucinations, distorted perceptions, pulse rate increase, intracranial pressure increase. An experimental teratogen. Experimental reproductive effects. When heated to decomposition it emits toxic fumes of NOx and HCl
Metabolism
Orphenadrine is almost completely metabolised to at least
8 metabolites in the liver.
It is mainly excreted in the urine as metabolites and small
amounts of unchanged drug
ORPHENADRINE HYDROCHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 114)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32038 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30241 | 58 |
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 | mcbio_sales@163.com | China | 2251 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38463 | 58 | |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49979 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
| Shanghai Acmec Biochemical Technology Co., Ltd. | +undefined18621343501 | product@acmec-e.com | China | 33338 | 58 |
| Aladdin Scientific | +1-+1(833)-552-7181 | sales@aladdinsci.com | United States | 57505 | 58 |
| SHANGHAI KEAN TECHNOLOGY CO., LTD. | +8613817748580 | cooperation@kean-chem.com | China | 40066 | 58 |
View Lastest Price from ORPHENADRINE HYDROCHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-01 | Orphenadrine hydrochloride
341-69-5
|
US $29.00 / mg | 99.54% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-01 | Orphenadrine hydrochloride
341-69-5
|
US $29.00 / mg | 99.54% | 10g | TargetMol Chemicals Inc. |
-
- Orphenadrine hydrochloride
341-69-5
- US $29.00 / mg
- 99.54%
- TargetMol Chemicals Inc.
-
- Orphenadrine hydrochloride
341-69-5
- US $29.00 / mg
- 99.54%
- TargetMol Chemicals Inc.
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N,N-Dimethyl-2-(o-methyl-alpha-phenylbenzyloxy)ethylamine hydrochloride
o-Methyldiphenhydramine hydrochloride, N,N-Dimethyl-2-(2-methylbenzhydryloxy)ethylamine hydrochloride, β-Dimethylaminoethyl 2-methylbenzhydryl ether hydrochloride
Orphenadrine hydrochloride,99%
Orphenadrine hydrochloride CRS
OrphenadrineHydrochloride>
ORPHENADRINE HYDROCHLORIDE ISO 9001：2015 REACH
Ionotropic glutamate receptors,Orphenadrine hydrochloride,spasticity,HSP27,parkinson's syndrome,PBR,Inhibitor,inhibit,CGC cells,iGluR,neuroprotective properties,Orphenadrine
Phenylbutazone Impurity 20
Orphenadrine Hydrochloride, ≥ 98.0%
Orphenadrine hydrochloride in methanol
341-69-5
C18H23NOHCl
Building Blocks
Amine Salts
Nitrogen Compounds
Organic Building Blocks
API