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3-Azabicyclo[3.1.0]hexane-2-carbonitrile, 6,6-dimethyl-, (1R,2S,5S)-

3-Azabicyclo[3.1.0]hexane-2-carbonitrile, 6,6-dimethyl-, (1R,2S,5S)- Structure
3-Azabicyclo[3.1.0]hexane-2-carbonitrile, 6,6-dimethyl-, (1R,2S,5S)- structure
CAS No.
1037559-82-2
Chemical Name:
3-Azabicyclo[3.1.0]hexane-2-carbonitrile, 6,6-dimethyl-, (1R,2S,5S)-
Synonyms
PF-07321332 Impurity 90;Nirmatrelvir Impurity 60;(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-carbonitrile;3-Azabicyclo[3.1.0]hexane-2-carbonitrile, 6,6-dimethyl-, (1R,2S,5S)-
CBNumber:
CB68348658
Molecular Formula:
C8H12N2
Molecular Weight:
136.19
MDL Number:
MOL File:
1037559-82-2.mol
MSDS File:
SDS
Last updated:2023-05-15 10:43:32
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3-Azabicyclo[3.1.0]hexane-2-carbonitrile, 6,6-dimethyl-, (1R,2S,5S)- Properties

Boiling point 233.5±23.0 °C(Predicted)
Density 1.06±0.1 g/cm3(Predicted)
pka 7.76±0.60(Predicted)

3-Azabicyclo[3.1.0]hexane-2-carbonitrile, 6,6-dimethyl-, (1R,2S,5S)- Chemical Properties,Uses,Production

Uses

(1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-carbonitrile is a boceprevir bicyclic [3.1.0]??proline intermediate, a key structural feature in the preparation of Boceprevir Merck’s drug for the treatment of hepatitis C.

3-Azabicyclo[3.1.0]hexane-2-carbonitrile, 6,6-dimethyl-, (1R,2S,5S)- synthesis

773837-37-9
159172-92-6
1037559-82-2
Synthesis of 3-Azabicyclo[3.1.0]hexane-2-carbonitrile, 6,6-dimethyl-, (1R,2S,5S)- from sodium:cyanide and 3-Azabicyclo[3.1.0]hexan-2-one,6,6-dimethyl-,(1R-cis)-(9CI)

3-Azabicyclo[3.1.0]hexane-2-carbonitrile, 6,6-dimethyl-, (1R,2S,5S)- Preparation Products And Raw materials

Raw materials

3-Azabicyclo[3.1.0]hexan-2-one,6,6-dimethyl-,(1R-cis)-(9CI) 3-Azabicyclo[3.1.0]hex-2-ene, 6,6-dimethyl-, (1R,5S)- sodium:cyanide

Preparation Products

3-Azabicyclo[3.1.0]hexane-2-carbonitrile, 6,6-dimethyl-, (1R,2S,5S)- Suppliers

Global( 4)Suppliers
Supplier Tel Email Country ProdList Advantage
China National Standard Pharmaceutical Corporation Limited 		+8615391658522 overseasales@yongstandards.com China 11927 58
Hubei Yangxin Medical Technology Co., Ltd. 15374522761 3003392093@qq.com China 8046 55
QUALITY CONTROL SOLUTIONS LTD. 13670046396 ORDERS@QCSRM.COM China 18865 58
Shanghai Haohong Pharmaceutical Co., Ltd. 400-400-8210725 4008210725 malulu@leyan.com China 40036 58
Supplier Advantage
China National Standard Pharmaceutical Corporation Limited 		58
Hubei Yangxin Medical Technology Co., Ltd. 55
QUALITY CONTROL SOLUTIONS LTD. 58
Shanghai Haohong Pharmaceutical Co., Ltd. 58
3-Azabicyclo[3.1.0]hexane-2-carbonitrile, 6,6-dimethyl-, (1R,2S,5S)- (1R,2S,5S)-6,6-Dimethyl-3-azabicyclo[3.1.0]hexane-2-carbonitrile PF-07321332 Impurity 90 Nirmatrelvir Impurity 60 1037559-82-2