ChemicalBook >> CAS DataBase List >>5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE

5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE

5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE structure

CAS No.: 189744-46-5

Chemical Name:: 5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE

Synonyms: RO 10-5824;Ro 10-5824 dihydrochloride;2-methyl-5-[(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)methyl]pyrimidin-4-amine;4-Pyrimidinamine, 5-[(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)methyl]-2-methyl-;5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE

CBNumber:: CB6848552

Molecular Formula:: C17H20N4

Molecular Weight:: 280.37

MDL Number:: MFCD08703115

MOL File:: 189744-46-5.mol

Last updated:2023-05-04 17:34:35

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5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE Properties

Boiling point	456.7±45.0 °C(Predicted)
Density	1.186±0.06 g/cm3(Predicted)
storage temp.	Desiccate at RT
pka	6.49±0.40(Predicted)
FDA UNII	8X35VUU4YY

5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Tocris	2329	Ro10-5824dihydrochloride ≥99%(HPLC)	189744-46-5	10	$154	2021-12-16	Buy
Tocris	2329	Ro10-5824dihydrochloride ≥99%(HPLC)	189744-46-5	50	$628	2021-12-16	Buy
TRC	R637503	Ro10-5824	189744-46-5	25mg	$210	2021-12-16	Buy
Usbiological	256473	Ro 10-5824 dihydrochloride	189744-46-5	10mg	$403	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0372993	5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE 95.00%	189744-46-5	5MG	$498.69	2021-12-16	Buy

Product number	Packaging	Price	Buy
2329	10	$154	Buy
2329	50	$628	Buy
R637503	25mg	$210	Buy
256473	10mg	$403	Buy
CHM0372993	5MG	$498.69	Buy

5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE Chemical Properties,Uses,Production

Uses

The dopamine receptors play important role in cognition, memory, learning, and motor control (1). These receptors have been implicated as a therapeutic target for many psychiatric and neurological disorders. Ro 10-5824 Dihydrochloride is a selective dopamine D4?receptor partial agonist (2).

Definition

ChEBI: 2-methyl-5-[(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)methyl]-4-pyrimidinamine is an aminopyrimidine.

Biological Activity

Selective dopamine D 4 receptor partial agonist (EC 50 = 205 nM) that binds with high affinity (K i = 5.2 nM). Displays 250-fold selectivity over D 3 receptors and > 1000-fold selectivity over D 2 , D 1 and D 5 receptors.

5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE Suppliers

Global( 27)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32165	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
3B Pharmachem (Wuhan) International Co.,Ltd.	821-50328103-801 18930552037	3bsc@sina.com	China	15839	69
EMMX Biotechnology LLC	888-539-0666	info@emmx.com	United States	8447	60
Shanghai Rechem science Co., Ltd.	21-31433387 15618786686	sales@rechemscience.com	China	2992	58
Energy Chemical	021-58432009 400-005-6266	marketing@energy-chemical.com	China	44918	58
InvivoChem	13549236410	sales@invivochem.cn	China	6753	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
InvivoChem	58
3B Pharmachem (Wuhan) International Co.,Ltd.	69
EMMX Biotechnology LLC	60
Shanghai Rechem science Co., Ltd.	58
Energy Chemical	58
InvivoChem	58

189744-46-5(5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE)Related Search:

4-Amino-5-aminomethyl-2-methylpyrimidine 5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride

RO 10-5824 5-[(3,6-DIHYDRO-4-PHENYL-1(2H)-PYRIDINYL)METHYL]-2-METHYL-4-PYRIMIDINAMINE DIHYDROCHLORIDE Ro 10-5824 dihydrochloride 2-methyl-5-[(4-phenyl-3,6-dihydro-2H-pyridin-1-yl)methyl]pyrimidin-4-amine 4-Pyrimidinamine, 5-[(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)methyl]-2-methyl- 189744-46-5 C17H20N42HCl