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levopropoxyphene

CAS No.
2338-37-6
Chemical Name:
levopropoxyphene
Synonyms
HSDB 3414;l-Propoxyphene;Levopropossifene;levopropoxyphene;Levopropoxyphenum;levopropoxyphene USP/EP/BP;(1R,2S)-1-benzyl-3-dimethylamino-2-methyl-1-phenylpropyl propionate;(1R,2S)-3-(Dimethylamino)-2-methyl-1-phenyl-1-(phenylmethyl)propyl propanoate;Benzeneethanol, α-[(1S)-2-(dimethylamino)-1-methylethyl]-α-phenyl-, 1-propanoate, (αR)-
CBNumber:
CB6875136
Molecular Formula:
C22H29NO2
Molecular Weight:
339.47116
MDL Number:
MFCD00866848
MOL File:
2338-37-6.mol
MSDS File:
SDS
Last updated:2023-05-04 17:34:36

levopropoxyphene Properties

Melting point 75-76°
alpha D25 -68.2° (c = 0.6 in chloroform)
Boiling point 444.0±45.0 °C(Predicted)
Density 1.038±0.06 g/cm3(Predicted)
pka 9.19±0.28(Predicted)
FDA UNII U75VZ9PK1J

levopropoxyphene Chemical Properties,Uses,Production

Uses

Antitussive.

Definition

ChEBI: Levopropoxyphene is a 1-benzyl-3-(dimethylamino)-2-methyl-1-phenylpropyl propanoate. It has a role as an antitussive. It is an enantiomer of a dextropropoxyphene.

brand name

Novrad(Lilly).

Biological Functions

Levopropoxyphene is the L-isomer of the analgesic agonist dextropropoxyphene. Levopropoxyphene is only mildly antitussive and is rarely used. It has no CNS effects. Side effects include dizziness and nausea. It is available as the napsylate derivative (Novrad) and is taken orally in the form of a liquid or less frequently as a capsule.

levopropoxyphene Preparation Products And Raw materials

Raw materials

Preparation Products

(1R,2S)-1-benzyl-3-dimethylamino-2-methyl-1-phenylpropyl propionate levopropoxyphene Levopropoxyphenum (1R,2S)-3-(Dimethylamino)-2-methyl-1-phenyl-1-(phenylmethyl)propyl propanoate Benzeneethanol, α-[(1S)-2-(dimethylamino)-1-methylethyl]-α-phenyl-, 1-propanoate, (αR)- levopropoxyphene USP/EP/BP HSDB 3414 Levopropossifene l-Propoxyphene 2338-37-6