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Rutaecarpine

Rutaecarpine structure

CAS No.: 20575-76-2

Chemical Name:: Rutaecarpine

Synonyms: Ai3-51108;Nsc 255317;Brn 2116874;Rutaecarpine;3,3'-HEXAMETHYLENEBIS(1,1-DIMETHYLUREA);1,1'-Hexamethylenebis[3,3-dimethylurea];Urea, 1,1'-hexamethylenebis(3,3-dimethyl-;1,1-(Hexane-1,6-diyl)bis(3,3-dimethylurea);N,N''-1,6-Hexanediylbis[N',N'-dimethylurea];1,1'-(Hexane-1,6-diyl)bis(3,3-dimethylurea)

CBNumber:: CB6975933

Molecular Formula:: C12H26N4O2

Molecular Weight:: 258.36

MDL Number:: MFCD00025668

MOL File:: 20575-76-2.mol

MSDS File:: SDS

Last updated:2023-05-09 09:30:48

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Rutaecarpine Properties

Boiling point	512.3±33.0 °C(Predicted)
Density	1.021±0.06 g/cm3(Predicted)
pka	13.98±0.46(Predicted)
EWG's Food Scores	1
FDA UNII	5Q7CEJ9UES

Rutaecarpine price More Price(1)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	S590355	3,3'-HEXAMETHYLENEBIS(1,1-DIMETHYLUREA) Aldrich	20575-76-2	250mg	$29.8	2024-03-01	Buy

Product number	Packaging	Price	Buy
S590355	250mg	$29.8	Buy

Rutaecarpine Chemical Properties,Uses,Production

Biological Functions

Rutaecarpine also inhibits accumulation of macrophages and cholesterol in atherosclerotic lesions and increases cholesterol excretion in other animal models. Additionally, rutaecarpine inhibits hypoxia-induced production of ROS and lactate dehydrogenase and suppresses apoptosis in myocardiocytes. In other cellular models, rutaecarpine decreases corticosterone production, potentially through inhibition of cAMP, 3β-hydroxysteroid dehydrogenase, and 11β-hydroxylase activity.

Biological Activity

Rutaecarpine is an indoloquinazoline alkaloid originally found in Evodia; it exhibits anti-inflammatory, anti-atherosclerotic, cardioprotective, anorexigenic, and anti-obesity activities. Rutaecarpine inhibits COX-2 and also decreases food intake, weight gain, and serum glucose, leptin, and insulin levels in vivo by inhibiting expression of neuropeptide Y and AgRP.

Mechanism of action

Rutaecarpine also inhibits production of ROS, NO, and iNOS, potentially through inhibition of NADPH oxidase. In macrophages, rutaecarpine inhibits arachidonic acid release and decreases production of prostaglandin E2 (PGE2); in other in vitro models, it inhibits collagen-stimulated formation of thromboxane B2 and inosine monophosphate.

Rutaecarpine Preparation Products And Raw materials

Raw materials

Preparation Products

Rutaecarpine Suppliers

Global( 44)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29811	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	22783	58
Dayang Chem (Hangzhou) Co.,Ltd.	571-88938639 +8617705817739	info@dycnchem.com	China	52849	58
Changsha Staherb Natural Ingredients Co., Ltd.	+86-0731-84213302 +86-18374838656	info@staherb.cn	China	1025	58
PT CHEM GROUP LIMITED		peter68@ptchemgroup.com	China	35425	58
GIHI CHEMICALS CO.,LIMITED	+8618058761490	info@gihichemicals.com	China	49978	58
SUZHOU SENFEIDA CHEMICAL CO.,LTD	+86-0512-83500002 +8615195660023	sales@senfeida.com	China	23046	58
Zhengzhou Guancheng Laboratory equipment Sales	0371-88888888 272369594	2723695949@qq.com	China	4890	50
Shanghai Jizhi Biochemical Technology Co. Ltd.	4009004166/18616739031 18616739031	3007523370@qq.com	China	52693	58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd	15229059051	1027@dideu.com	China	9996	58

Supplier	Advantage
career henan chemical co	58
Dideu Industries Group Limited	58
Dayang Chem (Hangzhou) Co.,Ltd.	58
Changsha Staherb Natural Ingredients Co., Ltd.	58
PT CHEM GROUP LIMITED	58
GIHI CHEMICALS CO.,LIMITED	58
SUZHOU SENFEIDA CHEMICAL CO.,LTD	58
Zhengzhou Guancheng Laboratory equipment Sales	50
Shanghai Jizhi Biochemical Technology Co. Ltd.	58
Shaanxi DIDU pharmaceutical and Chemical Co., Ltd	58

Preparation of Myricetin
Myricetin(MYR) belongs to flavonoids, mainly exists in the stems and leaves of vine tea or the bark and leaves of bayberry.
Sep 15，2022

View Lastest Price from Rutaecarpine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-28	Rutaecarpine 20575-76-2	US $500.00-400.00 / kg	1kg	98%	1000	Changsha Staherb Natural Ingredients Co., Ltd.
	2020-02-04	Rutaecarpine 20575-76-2	US $1.00 / KG	1KG	98% HPLC	10 tons	Career Henan Chemical Co

Rutaecarpine
20575-76-2
US $500.00-400.00 / kg
98%
Changsha Staherb Natural Ingredients Co., Ltd.

Rutaecarpine
20575-76-2
US $1.00 / KG
98% HPLC
Career Henan Chemical Co

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3-[6-(dimethylcarbamoylamino)hexyl]-1,1-dimethyl-urea 1,1'-Hexamethylenebis[3,3-dimethylurea] N,N''-1,6-Hexanediylbis[N',N'-dimethylurea] Rutaecarpine Ai3-51108 Brn 2116874 Nsc 255317 Urea, 1,1'-hexamethylenebis(3,3-dimethyl- Urea, N,N''-1,6-hexanediylbis(N',N'-dimethyl- (9ci) 3,3'-HEXAMETHYLENEBIS(1,1-DIMETHYLUREA) 1,1-(Hexane-1,6-diyl)bis(3,3-dimethylurea) Urea, N,N''-1,6-hexanediylbis[N',N'-dimethyl- 1,1'-(Hexane-1,6-diyl)bis(3,3-dimethylurea) 20575-76-2 82-26-4