gemcitabine
- CAS No.
- 103882-84-4
- Chemical Name:
- gemcitabine
- Synonyms
- C056507;2',2'-Dfdc;2'-Deoxy-2'-difluorocytidine;Gemcitabine, (alpha-D-threo-pentofuranosyl)-isomer;2'-Deoxy-2',2''-difluorocytidine-5'-o-monophosphate;4-?amino-?1-?(2-?deoxy-?2,?2-?difluoro-?D-?erythro-?pentofuranosyl)?-2(1H)?-?Pyrimidinone
- CBNumber:
- CB71361011
- Molecular Formula:
- C9H11F2N3O4
- Molecular Weight:
- 263.2
- MDL Number:
- MOL File:
- 103882-84-4.mol
Boiling point | 482.7±55.0 °C(Predicted) |
---|---|
Density | 1.4034 (estimate) |
solubility | DMSO (Slightly), Methanol (Slightly) |
form | Solid |
pka | 11.65±0.70(Predicted) |
color | White |
FDA UNII | B76N6SBZ8R |
gemcitabine Chemical Properties,Uses,Production
Uses
Gemcitabine is a nucleoside analog with anti-cancer properties. An inhibitor of DNA synthesis active on solid tumors.
Definition
ChEBI: Gemcitabine is a 2'-deoxycytidine having geminal fluoro substituents in the 2'-position. An inhibitor of ribonucleotide reductase, gemcitabine is used in the treatment of various carcinomas, particularly non-small cell lung cancer, pancreatic cancer, bladder cancer and breast cancer. It has a role as a photosensitizing agent, a DNA synthesis inhibitor, a prodrug, an EC 1.17.4.1 (ribonucleoside-diphosphate reductase) inhibitor, an environmental contaminant, a xenobiotic, a radiosensitizing agent, an antineoplastic agent, an antimetabolite, an antiviral drug and an immunosuppressive agent. It is an organofluorine compound and a pyrimidine 2'-deoxyribonucleoside.
gemcitabine Preparation Products And Raw materials
Raw materials
Preparation Products
gemcitabine Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Shijiazhuang Gantuo Biotechnology Co., Ltd | +8613373514458 | gantuo02@cngantuo.com | China | 218 | 58 |
Hebei Miaoyin Technology Co.,Ltd | +86-17367732028 +86-17367732028 | kathy@hbyinsheng.com | China | 3582 | 58 |
BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
BOC Sciences | 16314854226 | info@bocsci.com | United States | 9926 | 65 |
Aikon International Limited | 025-66113011 13155353615 | qzhang@aikonchem.com | China | 15396 | 58 |
Energy Chemical | 021-58432009 400-005-6266 | marketing@energy-chemical.com | China | 44941 | 58 |
Supplier | Advantage |
---|---|
Shijiazhuang Gantuo Biotechnology Co., Ltd | 58 |
Hebei Miaoyin Technology Co.,Ltd | 58 |
BOC Sciences | 65 |
BOC Sciences | 65 |
Aikon International Limited | 58 |
Energy Chemical | 58 |
View Lastest Price from gemcitabine manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2023-06-26 | Gemcitabine
103882-84-4
|
US $200.00 / kg | 1kg | 99% | 1000kg/Month | Hebei Mingeng Biotechnology Co., Ltd | ||
2023-04-11 | gemcitabine
103882-84-4
|
US $100.00 / mg | 25mg | 99% | 1000g | Shijiazhuang Gantuo Biotechnology Co., Ltd |
- Gemcitabine
103882-84-4
- US $200.00 / kg
- 99%
- Hebei Mingeng Biotechnology Co., Ltd
- gemcitabine
103882-84-4
- US $100.00 / mg
- 99%
- Shijiazhuang Gantuo Biotechnology Co., Ltd