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ChemicalBook >> CAS DataBase List >>8-[2-(4-benzhydrylpiperazin-1-yl)ethyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione

8-[2-(4-benzhydrylpiperazin-1-yl)ethyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione

8-[2-(4-benzhydrylpiperazin-1-yl)ethyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione Structure
8-[2-(4-benzhydrylpiperazin-1-yl)ethyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione structure
CAS No.
90749-32-9
Chemical Name:
8-[2-(4-benzhydrylpiperazin-1-yl)ethyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione
Synonyms
8-[2-(4-benzhydrylpiperazin-1-yl)ethyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione;8-[2-[4-(Diphenylmethyl)-1-piperazinyl]ethyl]-3,7-dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione;1H-Purine-2,6-dione, 8-[2-[4-(diphenylmethyl)-1-piperazinyl]ethyl]-3,9-dihydro-1-methyl-3-(2-methylpropyl)-
CBNumber:
CB71455954
Molecular Formula:
C29H36N6O2
Molecular Weight:
500.64
MDL Number:
MOL File:
90749-32-9.mol
Last updated:2025-04-18 09:52:37
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8-[2-(4-benzhydrylpiperazin-1-yl)ethyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione Properties

Melting point 202 °C(Solv: ethyl acetate (141-78-6))
Boiling point 692.5±65.0 °C(Predicted)
Density 1.210±0.06 g/cm3(Predicted)
pka 8.99±0.70(Predicted)
FDA UNII F427P36M7J

8-[2-(4-benzhydrylpiperazin-1-yl)ethyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
American Custom Chemicals Corporation API0025844 LAPRAFYLLINE 95.00% 90749-32-9 5MG $502.54 2021-12-16 Buy
Product number Packaging Price Buy
API0025844 5MG $502.54 Buy

8-[2-(4-benzhydrylpiperazin-1-yl)ethyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione Chemical Properties,Uses,Production

Uses

Laprafylline (S 9795), a xanthine derivative, is a bronchodilator. Laprafylline has potent anti-bronchoconstrictive effects, inhibiting action on mast cell degranulation and phosphodiesterase (PDE) activity (IC50 of 6 μM)[1].

in vivo

In male Sprague Dawley rats, Laprafylline (S 9795; 2.5-10mg/kg; iv) disappears rapidly from plasma with an elimination t1/2 of 0.8 h, regardless of the dose administered. The volume of distribution is high (about 3 L/kg) but total clearance is also high (about 40 mL/min/kg).

References

[1] G Bianchi, et al. Kinetics and brain uptake of S 9795, a new xanthine derivate, in rats. Eur J Drug Metab Pharmacokinet. 1989 Jul-Sep;14(3):201-8. DOI:10.1007/BF03190100

8-[2-(4-benzhydrylpiperazin-1-yl)ethyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione Preparation Products And Raw materials

Raw materials

Preparation Products

8-[2-(4-benzhydrylpiperazin-1-yl)ethyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione Suppliers

Global( 5)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 32219 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 11973 58
TargetMol Chemicals Inc. 15002134094 marketing@targetmol.cn China 19780 58
Sangon Biotech (Shanghai) Co.,Ltd. 400-821-026 Sales@sangon.com China 47255 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
Shanghai Yifei Biotechnology Co. , Ltd. 58
TargetMol Chemicals Inc. 58
Sangon Biotech (Shanghai) Co.,Ltd. 58

View Lastest Price from 8-[2-(4-benzhydrylpiperazin-1-yl)ethyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Laprafylline pictures 2024-11-19 Laprafylline
90749-32-9
 US $350.00-1130.00 / mg 100% 10g TargetMol Chemicals Inc.
  • Laprafylline pictures
  • Laprafylline
    90749-32-9
  • US $350.00-1130.00 / mg
  • 100%
  • TargetMol Chemicals Inc.

90749-32-9(8-[2-(4-benzhydrylpiperazin-1-yl)ethyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione)Related Search:

8-[2-(4-benzhydrylpiperazin-1-yl)ethyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione 2-(4-METHYL-1H-IMIDAZOL-2-YL)-ETHYLAMINE DIHYDROCHLORIDE Xanthine, 1,8-dimethyl-3-isobutyl- 1-methyl-3-propylxanthine 3-ISOBUTYL-1-METHYLXANTHINE
Aminophylline ENPROFYLLINE

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8-[2-(4-benzhydrylpiperazin-1-yl)ethyl]-1-methyl-3-(2-methylpropyl)-7H-purine-2,6-dione 8-[2-[4-(Diphenylmethyl)-1-piperazinyl]ethyl]-3,7-dihydro-1-methyl-3-(2-methylpropyl)-1H-purine-2,6-dione 1H-Purine-2,6-dione, 8-[2-[4-(diphenylmethyl)-1-piperazinyl]ethyl]-3,9-dihydro-1-methyl-3-(2-methylpropyl)- 90749-32-9 C29H36N6O2