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Disodium edetate dihydrate

CAS No.
6381-92-6
Chemical Name:
Disodium edetate dihydrate
Synonyms
EDTA ACID;EDTA disodium salt dihydrate;Ethylenediaminetetraacetic acid disodium salt dihydrate;VERSENE;Disodium edetate CRS;EDTA disodium salt 2-hydrate;HAMPENE ACID;EDTA SOLUTION;RED PRIMARY SOLUTION;Disodium Edetate Hydrate
CBNumber:
CB7153352
Molecular Formula:
C10H19N2NaO9
Molecular Weight:
334.26
MDL Number:
MFCD00150037
MOL File:
6381-92-6.mol
MSDS File:
SDS
Last updated:2024-11-19 15:53:33

Disodium edetate dihydrate Properties

Melting point 250 °C (dec.)(lit.)
Boiling point >100 °C
Density 1.01 g/mL at 25 °C
refractive index n20/D 1.363
FEMA 4520 | ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT
Flash point >100℃
storage temp. room temp
solubility 3  M NaOH: 100 mg/mL
pka pK1:1.99;pK2:2.67;pK3:6.16;pK4:10.26 (25°C)
form crystalline
color ≤5 (0.5 M)(APHA)
Odor Odorless
PH Range 4 - 5 at 10 g/l at 23 °C
PH 4.0-5.5 (25℃, 0.1M in H2O)
Water Solubility soluble
λmax λ: 260 nm Amax: 0.145
λ: 280 nm Amax: 0.025
BRN 3900609
Stability Stable. Incompatible with strong oxidizing agents.
InChIKey QCDUWWPHAVXXQS-UHFFFAOYSA-L
CAS DataBase Reference 6381-92-6(CAS DataBase Reference)
Substances Added to Food (formerly EAFUS) ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT
EWG's Food Scores 1
FDA UNII 7FLD91C86K
EPA Substance Registry System Ethylenediaminetetraacetic acid disodium salt dihydrate (6381-92-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Warning
Hazard statements  H332-H373
Precautionary statements  P260-P271-P304+P340+P312-P314-P501
Hazard Codes  Xi,Xn
Risk Statements  36-52/53-36/38-36/37/38-22
Safety Statements  26-61-37/39-36/37/39-36
WGK Germany  2
RTECS  AH4025000
3
TSCA  Yes
HS Code  29224995
Toxicity LD50 orally in Rabbit: > 2000 mg/kg
NFPA 704
1
2 0

Disodium edetate dihydrate price More Price(133)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 4010-OP OmniPur EDTA, Disodium Salt, Dihydrate - CAS 6381-92-6 - Calbiochem 6381-92-6 250g $91.4 2024-03-01 Buy
Sigma-Aldrich 324503 EDTA, Disodium Salt, Dihydrate, Molecular Biology Grade - CAS 6381-92-6 - Calbiochem 6381-92-6 100g $67.2 2024-03-01 Buy
Sigma-Aldrich 27285 Ethylenediaminetetraacetic acid disodium salt dihydrate meets analytical specification of Ph. Eur., BP, USP, FCC, 99.0-101.0% 6381-92-6 500g $203 2024-03-01 Buy
Sigma-Aldrich 27285 Ethylenediaminetetraacetic acid disodium salt dihydrate meets analytical specification of Ph. Eur., BP, USP, FCC, 99.0-101.0% 6381-92-6 1kg $285 2024-03-01 Buy
Sigma-Aldrich 27285 Ethylenediaminetetraacetic acid disodium salt dihydrate meets analytical specification of Ph. Eur., BP, USP, FCC, 99.0-101.0% 6381-92-6 6x1kg $1460 2024-03-01 Buy
Product number Packaging Price Buy
4010-OP 250g $91.4 Buy
324503 100g $67.2 Buy
27285 500g $203 Buy
27285 1kg $285 Buy
27285 6x1kg $1460 Buy

Disodium edetate dihydrate Chemical Properties,Uses,Production

Chemical Properties

White or almost white, crystalline powder.

Uses

Chelating agent; sequestering agent

Uses

Ethylenediaminetetraacetic acid disodium salt dihydrate is used as a chelator of divalent cations. It inhibits enzymes such as metalloproteases that require divalent cations for activity. It is also used in chelation therapy. It acts as a sequestering agent in shampoos, cleaners and other personal care products and serves as an anticoagulant for blood samples.

Uses

Ethylenediamine tetraacetic acid disodium dihydrate is used as chelating agent for metals and as pharmaceutic aid (chelating agent); as preservative in cosmetic products; anticoagulant.

Definition

ChEBI: A hydrate that is the dihydrate form of EDTA disodium salt.

General Description

Ethylenediaminetetraacetic acid disodium salt dehydrate is designated as Molecular Biology grade and is suitable for molecular biology applications. It has been analyzed for the presence of nucleases and proteases.

Biochem/physiol Actions

Zinc-dependent metalloproteinases, as well as other proteases that are stabilized by calcium, can be effectively inhibited by chelation of divalent metal ions with EDTA. Other chelators such as EGTA, specific for calcium, and 1,10-phenanthroline, highly specific for zinc, can be used to target these two different types of proteases.

Purification Methods

Analytical reagent grade material can be used as primary standard after drying at 80o. Commercial grade material can be purified by crystallisation from water or by preparing a 10% aqueous solution at room temperature, then adding ethanol slowly until a slight permanent precipitate is formed, filtering, and adding an equal volume of ethanol. The precipitate is filtered off onto a sintered-glass funnel, is washed with acetone, followed by diethyl ether, and dried in air overnight to give the dihydrate. Drying at 80o for at least 24hours converts it to the anhydrous form. [Beilstein 4 IV 2451.]

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Anhui Royal Chemical Co., Ltd.
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View Lastest Price from Disodium edetate dihydrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Disodium edetate dihydrate pictures 2024-11-28 Disodium edetate dihydrate
6381-92-6
US $100.00-75.00 / kg 1kg 99% 5000Ton HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
EDTA-2Na pictures 2024-11-28 EDTA-2Na
6381-92-6
US $0.00-0.00 / kg 1kg 99% 20MT Watson Biotechnology Co.,Ltd
Disodium edetate dihydrate pictures 2024-11-28 Disodium edetate dihydrate
6381-92-6
US $120.00 / kg 1kg 99% 20ton Hebei Zhuanglai Chemical Trading Co.,Ltd
  • EDTA-2Na pictures
  • EDTA-2Na
    6381-92-6
  • US $0.00-0.00 / kg
  • 99%
  • Watson Biotechnology Co.,Ltd
Disodium Dihydrogen Ethylenediaminetetraacetate Dihydrate [for Biochemical Research] Edetate DisodiuM, Dihydrate, Crystal, USP DisodiuM Dihydrogen EthylenediaMinetetraacetate  EthylenediaMinetetraacetic acid, disodiuM salt dihydrate, for analysis, 99+% 100GR EthylenediaMinetetraacetic acid, disodiuM salt dihydrate, for analysis, 99+% 1KG EthylenediaMinetetraacetic acid, disodiuM salt dihydrate, for analysis, 99+% 500GR Ethylenediaminetetraacetic Acid Disodium Salt EDTA 2Na ETA EthylenediaMinetetraacetic acid disodiuM solution EthylenediaMine Tetra—aceticAcid DisodiuM Salt (CoMplexoMetric Standard) ETHYLENEDINITRILOTETRAACETIC ACID DISODI TITRIPLEX III GR FOR ANALYSIS (ETHYLENED (Ethylenedinitrilo)tetraacetic Acid DisodiuM, Dihydrate, Reagent, ACS Edetate DisodiuM, Dihydrate, ACS Edetate disodiuM USP EDTA disodiuM salt dihydrate (coMplexoMetric standard) SodiuM 2,2'-((2-(bis(carboxyMethyl)aMino)ethyl)azanediyl)diacetate dihydrate EthylenediaMinetetraacetic acid disodiuM salt dihydrate, 99.0-101.0% EDTA-2Na(Ethylenediaminetetraacetic acid disodium salt) Ethylenediaminetetraacetic acid disodium salt dihydrate >=97.0% (KT) Ethylenediaminetetraacetic acid disodium salt, dihydrate≥ 99% (Titration) Ethylenediaminetetraacetic acid disodium salt, dihydrateUSP, 99.0-101.0% (Titration) Disodium ethylenediaminetetraacetate dihydrate, EDTA disodium salt, EDTA-Na2, Edathamil, Edetate disodium salt dihydrate, Sequestrene Na2 Edetate disodium salt dihydrate EDTA disodium salt Ethylened EDTA, 0.5M Solution, EDTA-Na EDTA Standard Solution, 1mL = 1mg CaCO EDTA, Disodium Salt, Dihydrate, 0.1M Volumetric Solution Titriplex III for analysis (ethylenedinitrilotetraacetic acid, disodium salt dihydrate) ACS,ISO,Reag. Ph Eur aceticacid,(ethylenedinitrilo)tetra-,disodiumsalt,dihydrate disodiumedtadihydrate ethylenediaminetetraaceticacidsodiumsaltdihydrate(disodiumedta ethylenediaminetetraaceticacidsodiumsaltdihydrate(disodiumedtadihydrate) glycine,n,n’-1,2-ethanediylbis(n-(carboxymethyl)-,disodiumsalt,dihydrate Glycine,N,N’-1,2-ethanediylbis[N-(carboxymethyl)-,disodiumsalt,dihydrate 1,2-DIAMINOETHANE-N,N,N',N'-TETRA-ACETIC ACID EDTA TITRANT EDTA REAGENT COMPLEXONE II(R) ETHYLENEBIS(IMINODIACETIC ACID) ETHYLENEDIAMINE-N,N,N',N'-TETRAACETIC ACID IDRANAL(R) BETZ 0640 VERSENE ACID TIMTEC-BB SBB008807 TITRIPLEX II TITRIPLEX II EDTA TITRIPLEX(R) II ETHYLENEDIAMINETETRAACETIC ACID 2 NA ETHYLENEDIAMINETETRAACETIC ACID,2 NA 2 H2O Ethylenediaminetetraacetic acid, disodium salt dihydrate, for analysis ACS, 99+% ETHYLENEDIAMINETETRAACETIC ACID EDTA DISODIUM SALT STANDARD SOLUTION, 1MOL/L ETHYLENEDIAMINETETRAACETIC ACID EDTA DISODIUM SALT DIHYDRATE, 99.5+% GR ACS ETHYLENEDIAMINETETRAACETIC ACID EDTA DISODIUM SALT DIHYDRATE, MOLECULAR BIOLOGY GRADE ETHYLENEDIAMINETETRAACETIC ACID EDTA DISODIUM SALT DIHYDRATE, PROTEOMICS GRADE EdtaDi-SodiumUsp/Acs/Fcc EdtaDisodiumSaltGr EdtaDisodiumBp EthyleneDiamineTetraaceticAcidDisodium(Edta2Na) EdtaDisodiumUsp EdtaDisodiumIp