Disodium edetate dihydrate
- CAS No.
- 6381-92-6
- Chemical Name:
- Disodium edetate dihydrate
- Synonyms
- EDTA ACID;EDTA disodium salt dihydrate;Ethylenediaminetetraacetic acid disodium salt dihydrate;VERSENE;Disodium edetate CRS;EDTA disodium salt 2-hydrate;HAMPENE ACID;EDTA SOLUTION;RED PRIMARY SOLUTION;Disodium Edetate Hydrate
- CBNumber:
- CB7153352
- Molecular Formula:
- C10H19N2NaO9
- Molecular Weight:
- 334.26
- MDL Number:
- MFCD00150037
- MOL File:
- 6381-92-6.mol
- MSDS File:
- SDS
Melting point | 250 °C (dec.)(lit.) |
---|---|
Boiling point | >100 °C |
Density | 1.01 g/mL at 25 °C |
refractive index |
n |
FEMA | 4520 | ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT |
Flash point | >100℃ |
storage temp. | room temp |
solubility | 3 M NaOH: 100 mg/mL |
pka | pK1:1.99;pK2:2.67;pK3:6.16;pK4:10.26 (25°C) |
form | crystalline |
color | ≤5 (0.5 M)(APHA) |
Odor | Odorless |
PH Range | 4 - 5 at 10 g/l at 23 °C |
PH | 4.0-5.5 (25℃, 0.1M in H2O) |
Water Solubility | soluble |
λmax |
λ: 260 nm Amax: 0.145 λ: 280 nm Amax: 0.025 |
BRN | 3900609 |
Stability | Stable. Incompatible with strong oxidizing agents. |
InChIKey | QCDUWWPHAVXXQS-UHFFFAOYSA-L |
CAS DataBase Reference | 6381-92-6(CAS DataBase Reference) |
Substances Added to Food (formerly EAFUS) | ETHYLENEDIAMINETETRAACETIC ACID DISODIUM SALT |
EWG's Food Scores | 1 |
FDA UNII | 7FLD91C86K |
EPA Substance Registry System | Ethylenediaminetetraacetic acid disodium salt dihydrate (6381-92-6) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | GHS07,GHS08 |
|||||||||
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Signal word | Warning | |||||||||
Hazard statements | H332-H373 | |||||||||
Precautionary statements | P260-P271-P304+P340+P312-P314-P501 | |||||||||
Hazard Codes | Xi,Xn | |||||||||
Risk Statements | 36-52/53-36/38-36/37/38-22 | |||||||||
Safety Statements | 26-61-37/39-36/37/39-36 | |||||||||
WGK Germany | 2 | |||||||||
RTECS | AH4025000 | |||||||||
F | 3 | |||||||||
TSCA | Yes | |||||||||
HS Code | 29224995 | |||||||||
Toxicity | LD50 orally in Rabbit: > 2000 mg/kg | |||||||||
NFPA 704 |
|
Disodium edetate dihydrate price More Price(133)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | 4010-OP | OmniPur EDTA, Disodium Salt, Dihydrate - CAS 6381-92-6 - Calbiochem | 6381-92-6 | 250g | $91.4 | 2024-03-01 | Buy |
Sigma-Aldrich | 324503 | EDTA, Disodium Salt, Dihydrate, Molecular Biology Grade - CAS 6381-92-6 - Calbiochem | 6381-92-6 | 100g | $67.2 | 2024-03-01 | Buy |
Sigma-Aldrich | 27285 | Ethylenediaminetetraacetic acid disodium salt dihydrate meets analytical specification of Ph. Eur., BP, USP, FCC, 99.0-101.0% | 6381-92-6 | 500g | $203 | 2024-03-01 | Buy |
Sigma-Aldrich | 27285 | Ethylenediaminetetraacetic acid disodium salt dihydrate meets analytical specification of Ph. Eur., BP, USP, FCC, 99.0-101.0% | 6381-92-6 | 1kg | $285 | 2024-03-01 | Buy |
Sigma-Aldrich | 27285 | Ethylenediaminetetraacetic acid disodium salt dihydrate meets analytical specification of Ph. Eur., BP, USP, FCC, 99.0-101.0% | 6381-92-6 | 6x1kg | $1460 | 2024-03-01 | Buy |
Disodium edetate dihydrate Chemical Properties,Uses,Production
Chemical Properties
White or almost white, crystalline powder.
Uses
Chelating agent; sequestering agent
Uses
Ethylenediaminetetraacetic acid disodium salt dihydrate is used as a chelator of divalent cations. It inhibits enzymes such as metalloproteases that require divalent cations for activity. It is also used in chelation therapy. It acts as a sequestering agent in shampoos, cleaners and other personal care products and serves as an anticoagulant for blood samples.
Uses
Ethylenediamine tetraacetic acid disodium dihydrate is used as chelating agent for metals and as pharmaceutic aid (chelating agent); as preservative in cosmetic products; anticoagulant.
Definition
ChEBI: A hydrate that is the dihydrate form of EDTA disodium salt.
General Description
Ethylenediaminetetraacetic acid disodium salt dehydrate is designated as Molecular Biology grade and is suitable for molecular biology applications. It has been analyzed for the presence of nucleases and proteases.
Biochem/physiol Actions
Zinc-dependent metalloproteinases, as well as other proteases that are stabilized by calcium, can be effectively inhibited by chelation of divalent metal ions with EDTA. Other chelators such as EGTA, specific for calcium, and 1,10-phenanthroline, highly specific for zinc, can be used to target these two different types of proteases.
Purification Methods
Analytical reagent grade material can be used as primary standard after drying at 80o. Commercial grade material can be purified by crystallisation from water or by preparing a 10% aqueous solution at room temperature, then adding ethanol slowly until a slight permanent precipitate is formed, filtering, and adding an equal volume of ethanol. The precipitate is filtered off onto a sintered-glass funnel, is washed with acetone, followed by diethyl ether, and dried in air overnight to give the dihydrate. Drying at 80o for at least 24hours converts it to the anhydrous form. [Beilstein 4 IV 2451.]
Disodium edetate dihydrate Preparation Products And Raw materials
Raw materials
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Preparation Products
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Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Anhui Royal Chemical Co., Ltd. | +86-25-86655873 +8613962173137 | marketing@royal-chem.com | China | 193 | 55 |
Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
Jiangsu Boquan Biotechnology Co., Ltd. | +86-18168774353 | boquanshengwu003@boquansw.com | China | 248 | 58 |
Shandong Deshang Chemical Co., Ltd. | +86-0531-8875-2665 +8613153039501 | info@deshangchem.com | China | 662 | 58 |
Aurora Industry Co., Ltd. | +86-13591747876 +86-13591747876 | alex1_auco@126.com | China | 277 | 58 |
Hebei Weibang Biotechnology Co., Ltd | +8615531157085 | abby@weibangbio.com | China | 8810 | 58 |
Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5857 | 58 |
Shanghai UCHEM Inc. | +862156762820 +86-13564624040 | sales@myuchem.com | China | 7514 | 58 |
Hebei Chuanghai Biotechnology Co,.LTD | +86-13131129325 | sales1@chuanghaibio.com | China | 5892 | 58 |
Hebei Kingfiner Technology Development Co.Ltd | +86-15532196582 +86-15373005021 | lisa@kingfinertech.com | China | 3010 | 58 |
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View Lastest Price from Disodium edetate dihydrate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
---|---|---|---|---|---|---|---|---|
2024-11-28 | Disodium edetate dihydrate
6381-92-6
|
US $100.00-75.00 / kg | 1kg | 99% | 5000Ton | HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD | ||
2024-11-28 | EDTA-2Na
6381-92-6
|
US $0.00-0.00 / kg | 1kg | 99% | 20MT | Watson Biotechnology Co.,Ltd | ||
2024-11-28 | Disodium edetate dihydrate
6381-92-6
|
US $120.00 / kg | 1kg | 99% | 20ton | Hebei Zhuanglai Chemical Trading Co.,Ltd |
- Disodium edetate dihydrate
6381-92-6
- US $100.00-75.00 / kg
- 99%
- HEBEI SHENGSUAN CHEMICAL INDUSTRY CO.,LTD
- EDTA-2Na
6381-92-6
- US $0.00-0.00 / kg
- 99%
- Watson Biotechnology Co.,Ltd
- Disodium edetate dihydrate
6381-92-6
- US $120.00 / kg
- 99%
- Hebei Zhuanglai Chemical Trading Co.,Ltd
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