2-CHLORO-4-(METHYLSULFONYL)ANILINE
- CAS No.
- 13244-35-4
- Chemical Name:
- 2-CHLORO-4-(METHYLSULFONYL)ANILINE
- Synonyms
- 2-CHLORO-4-METHYLSULPHONYLANILINE;TIMTEC-BB SBB003494;LABOTEST-BB LT00441295;2-chloro-4-mesylaniline;2-chloro-4-(methylsulfonyl)-anilin;2-CHLORO-4-(METHYLSULFONYL)ANILINE;4-amino-3-chlorophenylmethylsulfone;4-amino-3-chlorofenylomethylosulfon;4-amino-3-chlorophenylmethylsulphone;2-Chloro-4-methylsulphonylaniline,95%
- CBNumber:
- CB7160824
- Molecular Formula:
- C7H8ClNO2S
- Molecular Weight:
- 205.66
- MDL Number:
- MFCD00152349
- MOL File:
- 13244-35-4.mol
- MSDS File:
- SDS
Melting point | 191-198 °C |
---|---|
Boiling point | 400.1±45.0 °C(Predicted) |
Density | 1.2326 (rough estimate) |
refractive index | 1.6000 (estimate) |
storage temp. | 2-8°C |
form | Crystalline Powder |
pka | -0.60±0.10(Predicted) |
color | Pale purple to gray-brown |
CAS DataBase Reference | 13244-35-4(CAS DataBase Reference) |
EPA Substance Registry System | Benzenamine, 2-chloro-4-(methylsulfonyl)- (13244-35-4) |
2-CHLORO-4-(METHYLSULFONYL)ANILINE price More Price(10)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | S448281 | 2-CHLORO-4-(METHYLSULFONYL)-ANILINE Aldrich | 13244-35-4 | 50mg | $110 | 2024-03-01 | Buy |
AK Scientific | 5972AA | 2-Chloro-4-(methylsulfonyl)aniline | 13244-35-4 | 1g | $123 | 2021-12-16 | Buy |
SynQuest Laboratories | 8663-5-01 | 2-Chloro-4-(methylsulfonyl)aniline | 13244-35-4 | 5G | $149 | 2021-12-16 | Buy |
Matrix Scientific | 006907 | 2-Chloro-4-methylsulfonylaniline | 13244-35-4 | 5g | $175 | 2021-12-16 | Buy |
SynQuest Laboratories | 8663-5-01 | 2-Chloro-4-(methylsulfonyl)aniline | 13244-35-4 | 25g | $549 | 2021-12-16 | Buy |
2-CHLORO-4-(METHYLSULFONYL)ANILINE Chemical Properties,Uses,Production
Chemical Properties
pale purple to grey-brown crystalline powder
Uses
2-Chloro-4-methylsulphonylaniline can be used as organic synthesis intermediates and pharmaceutical intermediates, mainly used in laboratory research and development processes and pharmaceutical and chemical production processes.
Synthesis
A mixture of 2-chloro-4-methylsulfonyl-1- nitro-benzene (4.5 g, 19.10 mmol, 1 eq.) in EtOH (40 mL) and a saturated NH4Cl solution (10 mL) was heated to 90 °C, and then Fe (3.20 g, 57.29 mmol, 3 eq.) was added in one portion. The reaction mixture was stirred at 90 °C for 1 h, after which time TLC analysis (PE:EtOAc = 1:1, Rf(starting material) = 0.7, Rf(product) = 0.31) indicated that the reaction was complete. The reaction was diluted with water (50 mL) and extracted with EtOAc (100 mL x 3). The combined organic layers were washed with water (50 mL x 3) and brine (50 mL x 2), dried over anhydrous sodium sulfate, filtered, and concentrated under reduced pressure. The residue was purified by column chromatography (SiO2, PE:EtOAc = 4:1 to 2:1) to provide 2-chloro-4-methylsulfonyl-aniline (3.7 g, 17.99 mmol, 94.21% yield) as an off-white solid.
2-CHLORO-4-(METHYLSULFONYL)ANILINE Preparation Products And Raw materials
Raw materials
Preparation Products
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Suzhou Victorypharm Co.,Ltd. | +86-13916956214 | sales@victory-pharm.com | China | 1301 | 58 |
Shenzhen Nexconn Pharmatechs Ltd | +86-755-89396905 +86-15013857715 | admin@nexconn.com | China | 10312 | 58 |
Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49392 | 58 |
Richest Group Ltd | 18017061086 | oled@richest-group.com | CHINA | 5601 | 58 |
Career Henan Chemica Co | +86-0371-86658258 +8613203830695 | laboratory@coreychem.com | China | 30250 | 58 |
sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12382 | 58 |
Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49739 | 58 |
Zhengzhou Lingzhiyue Technology Co., Ltd | +86-0371-55074660 +86-13783527580 | Lingzhiyue@aliyun.com | China | 3152 | 58 |
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