ChemicalBook >> CAS DataBase List >>Polyinosinic acid
Polyinosinic acid
- CAS No.
- 30918-54-8
- Chemical Name:
- Polyinosinic acid
- Synonyms
- POLYINOSINIC ACID TRIPOTASSIUM SALT;Poly(rI);Poly(IMP);Inosine acid;Polyinosinic acid;Poly(5’-inosinicacid);POLY RL POTASSIUM SALT;POLY[I] POTASSIUM SALT;Polyinosinic Acid (90%);polyinosinicacidpot.salt
- CBNumber:
- CB7201291
- Molecular Formula:
- C10H13N4O8P
- Molecular Weight:
- 348.21
- MDL Number:
- MFCD00131982
- MOL File:
- 30918-54-8.mol
Last updated:2024-09-10 19:09:04
| storage temp. | −20°C |
|---|---|
| solubility | Methanol (Slightly), Water (Sparingly) |
| form | Solid |
| color | White to Off-White |
| InChI | InChI=1/C10H13N4O8P/c15-6-4(1-21-23(18,19)20)22-10(7(6)16)14-3-13-5-8(14)11-2-12-9(5)17/h2-4,6-7,10,15-16H,1H2,(H,11,12,17)(H2,18,19,20)/t4-,6-,7-,10-/s3 |
| InChIKey | GRSZFWQUAKGDAV-BFXIWLNFNA-N |
| SMILES | O[C@@H]1[C@@H]([C@@H](COP(O)(O)=O)O[C@H]1N1C=NC2C(NC=NC1=2)=O)O |&1:1,2,3,11,r| |
| FDA UNII | UM56ZHC52Q |
SAFETY
Risk and Safety Statements
| WGK Germany | 3 |
|---|---|
| F | 3-10-21 |
Polyinosinic acid price More Price(2)
Polyinosinic acid Chemical Properties,Uses,Production
Description
Polyinosinic acid Polycytidylic Acid, Sodium Salt, Double-Stranded is a TLR3 (Toll-like receptor 3) agonist. Known to induce interferon production. Hypochromicity: ≥40% at 248 nm. Extinction coefficient = 5000 M-1cm-1 at 260 nm, pH 7.0. Agent for generation of stable, mature dendritic cells (DC) and immunostimulant.
Chemical Properties
White or off-white powder, soluble in water, insoluble in organic solvents such as ethanol and acetaminophen.
Uses
Polyinosinic Acid is an oligolysines used in nucleic acid binding and other biomedical applications.
Application
Polyinosinic acid (Poly(I)) is a homopolymer of inosine that may be used with polycytidylic acid (poly(C)) to form the double-stranded homopolymer (Poly(I).Poly(C)). TLR3 recognizes double-stranded RNA and is a major effector of the immune response against viral pathogens. (Poly(I).Poly(C)) is a used as a model RNA to study cell signaling at the level of TLR3. Poly(IC) is a TRIF-dependent toll-like receptor-3 (TLR3) ligand.
Polyinosinic acid Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 205)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| HangZhou RunYan Pharma Technology Co.,LTD. | +8618882027439 | sales2@runyanpharma.com | China | 302 | 58 |
| Hangzhou Meiya Pharmaceutical Co Ltd | +86-021-33686691 +8618001850931 | sales@meiyapharm.com | China | 58 | 58 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 18751 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21634 | 55 |
| Nanjing Finetech Chemical Co., Ltd. | 025-85710122 17714198479 | sales@fine-chemtech.com | CHINA | 885 | 55 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29880 | 58 |
| Jinan Carbotang Biotech Co.,Ltd. | +8615866703830 | figo.gao@foxmail.com | China | 8497 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 1169 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
View Lastest Price from Polyinosinic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-12-23 | Polyinosinic acid sodium salt，Poly I, POLY I-Na
30918-54-8
|
US $0.00 / kg | 1kg | 90.0%Min. HPLC | 1000kg | HangZhou RunYan Pharma Technology Co.,LTD. | |
 |
2024-03-11 | Polyinosinic acid sodium salt (PI)
30918-54-8
|
US $0.00-0.00 / kg | 1kg | ≥90.0% | 10 tons | Hangzhou Meiya Pharmaceutical Co Ltd | |
 |
2023-10-18 | POLYINOSINIC ACID (5') POTASSIUM SALT
30918-54-8
|
US $5.76 / KG | 10KG | 99% | 100kg | Wuhan Han Sheng New Material Technology Co.，Ltd |
-
- Polyinosinic acid sodium salt，Poly I, POLY I-Na
30918-54-8
- US $0.00 / kg
- 90.0%Min. HPLC
- HangZhou RunYan Pharma Technology Co.,LTD.
-
- Polyinosinic acid sodium salt (PI)
30918-54-8
- US $0.00-0.00 / kg
- ≥90.0%
- Hangzhou Meiya Pharmaceutical Co Ltd
-
- POLYINOSINIC ACID (5') POTASSIUM SALT
30918-54-8
- US $5.76 / KG
- 99%
- Wuhan Han Sheng New Material Technology Co.，Ltd
30918-54-8(Polyinosinic acid)Related Search:
POLY RL POTASSIUM SALT
POLYINOSINIC ACID POT. SALT, LYOPH., MR ~1200000
5'-Inosinic acid polymers
Polyinosinic acid
Polyinosinic acid (Poly I)
5’-Inosinicacid,homopolymer
Poly(5’-inosinicacid)
Poly(IMP)
Poly(rI)
POLYINOSINIC ACID POTASSIUM SALT
POLYINOSINIC ACID (5') POTASSIUM SALT
POLY[I] POTASSIUM SALT
polyinosinicacidpot.salt
[(2R,3S,4R,5R)-3,4-dihydroxy-5-(6-oxo-3H-purin-9-yl)-2-oxolanyl]methyl dihydrogen phosphate
Polyinosinic Acid (90%)
Polyinosinic acid USP/EP/BP
Polyinosinic acid sodium salt，Poly I, POLY I-Na
Polyinosinic acid sodium
Inosine acid
POLYINOSINIC ACID TRIPOTASSIUM SALT
Polyinosinic acid sodium salt (PI)
3'-5' cyclic adenosine monophosphate sodium
5'-Inosinic acid polymers
30918-54-8
C10H13N4O8Pn
BioChemical
Biochemicals and Reagents
Nucleosides, Nucleotides, Oligonucleotides
Synthetic Oligonucleotides and Related Reagents
Material
Nucleoside Mono