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Z-Lys(Z)-OH

CAS No.
405-39-0
Chemical Name:
Z-Lys(Z)-OH
Synonyms
Z-Lys;CBZ-LYS(CBZ)-OH;Cbz-Lys(Z)-OH;Z-LYS(Z);NSC 88474;Z-LYS(Z)-OH;Z-L-Lys(Z)-OH;Z-LYSINE(Z)-OH;DI-N-CBZ-L-LYSINE;Cbz-L-Lys(Cbz)-OH
CBNumber:
CB7208816
Molecular Formula:
C22H26N2O6
Molecular Weight:
414.45
MDL Number:
MFCD00037822
MOL File:
405-39-0.mol
MSDS File:
SDS
Last updated:2024-03-28 11:36:32

Z-Lys(Z)-OH Properties

Melting point 76-78°C
Boiling point 659.0±55.0 °C(Predicted)
Density 1.238±0.06 g/cm3(Predicted)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 3.97±0.21(Predicted)
color White to Off-White
BRN 1897206
InChIKey BLZXFNUZFTZCFD-IBGZPJMESA-N
SMILES C(O)(=O)[C@H](CCCCNC(OCC1=CC=CC=C1)=O)NC(OCC1=CC=CC=C1)=O
CAS DataBase Reference 405-39-0(CAS DataBase Reference)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
WGK Germany  3

Z-Lys(Z)-OH price More Price(52)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 96835 Z-Lys(Z)-OH ≥98.0% (TLC) 405-39-0 5g $63.3 2023-06-20 Buy
TRC B410905 N2,N6-Bis(benzyloxycarbonyl)-L-lysine 405-39-0 25g $110 2021-12-16 Buy
TRC B410905 N2,N6-Bis(benzyloxycarbonyl)-L-lysine 405-39-0 50g $145 2021-12-16 Buy
Usbiological 262704 N2,N6-Bis-cbz-L-lysine 405-39-0 25g $333 2021-12-16 Buy
TRC B410905 N2,N6-Bis(benzyloxycarbonyl)-L-lysine 405-39-0 10g $60 2021-12-16 Buy
Product number Packaging Price Buy
96835 5g $63.3 Buy
B410905 25g $110 Buy
B410905 50g $145 Buy
262704 25g $333 Buy
B410905 10g $60 Buy

Z-Lys(Z)-OH Chemical Properties,Uses,Production

Chemical Properties

White Solid

Uses

Protected L-lysine

Definition

Z-Lys(Z)-OH is a lysine derivative.

Synthesis

A 250 mL three-necked flask was loaded consecutively with water (20 mL), 1,4-dioxane (20 mL), and L-lysine (2.1 g, 14.4 mmol). The mixture was stirred until complete dissolution. The pH was adjusted to about 10.5 by the addition of 30% NaOH. Benzyl chloroformate (5.2 g, 30.6 mmol) was added while maintaining the pH at about 1011 by adding at the same time 30% NaOH. At the end of the addition, the reaction was stirred at 20° C. for about 1 hour. The pH was adjusted to 5 with 37% HCl. Ethyl acetate (30 mL) was added and the pH was adjusted to 1 with 37% HCl. The mixture was stirred at room temperature for about 30 minutes, the organic layer was separated and the aqueous layer was extracted with ethyl acetate (20 mL). The combined organic layer was washed with brine (30 mL) and dried over Na2SO4. Then, the solvent was evaporated to yield Z-Lys(Z)-OH as a yellowish oil (6.0 g, 99%).

1155-64-2
501-53-1
405-39-0
Synthesis of Z-Lys(Z)-OH from N6-Cbz-L-Lysine and Benzyl chloroformate
Global( 208)Suppliers
Supplier Tel Email Country ProdList Advantage
Sichuan HongRi Pharma-Tech Co.,Ltd
+86-028-64841719 +8617390183901 daisy@enlaibio.com China 1106 58
Capot Chemical Co.,Ltd.
+86-(0)57185586718 +86-13336195806 sales@capot.com China 29791 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
AB PharmaTech,LLC
323-480-4688 sales@acrospharmatech.com United States 989 55
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10311 58
Xiamen AmoyChem Co., Ltd
+86-86-5926051114 +8618959220845 sales@amoychem.com China 6383 58
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29811 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17365 58

View Lastest Price from Z-Lys(Z)-OH manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Cbz-L-Lys(Cbz)-OH pictures 2024-12-23 Cbz-L-Lys(Cbz)-OH
405-39-0
US $0.00-0.00 / kg 1kg 98% 1T+ Sichuan HongRi Pharma-Tech Co.,Ltd
Z-Lys(Z)-OH pictures 2022-02-22 Z-Lys(Z)-OH
405-39-0
US $0.00 / KG 1KG 97.1% 100 tons Honest Joy Holdings Limited
Z-LYS(Z)-OH pictures 2020-01-10 Z-LYS(Z)-OH
405-39-0
US $3.00 / KG 1KG 98% 200KG Career Henan Chemical Co
  • Z-Lys(Z)-OH pictures
  • Z-Lys(Z)-OH
    405-39-0
  • US $0.00 / KG
  • 97.1%
  • Honest Joy Holdings Limited
  • Z-LYS(Z)-OH pictures
  • Z-LYS(Z)-OH
    405-39-0
  • US $3.00 / KG
  • 98%
  • Career Henan Chemical Co
DI-N-CBZ-L-LYSINE DICARBOBENZOXY-L-LYSINE Z-LYSINE(Z)-OH Z-LYS(Z)-OH N-ALPHA,EPSILON-BIS-Z-L-LYSINE N-ALPHA,N-EPSILON-DI-Z-L-LYSINE N-ALPHA, N-EPSILON-DIBENZYLOXYCARBONYL-L-LYSINE N-ALPHA-N-EPSILON-DICARBOBENZOXY-L-LYSINE N-ALPHA-N-EPSILON-DI-CBZ-L-LYSINE N,N'-DI-CBZ-L-LYSINE di-N-CBZ-L-Lysine di-N-Carbobenzyloxy-L-lysine Cbz-L-Lys(Cbz)-OH Nα,ε-Bis-Z-L-lysine≥ 99% (HPLC) N,N-di-cbz-L-lysine free acid N2,N6-dibenzyloxycarbonyl-L-lysine NA,NE-DIBENZYLOXYCARBONYL-L-LYSINE Z-LYS(Z) L-Lysine, N2,N6-bis[(phenylmethoxy)carbonyl]- N1,N6-DI-CBZ-L-LYSINE N,N'-di-carbobenzyloxy-L-lysine N,Nμ-Di-Cbz-L-lysine, Nα,Nε-Di-Z-L-lysine N2,N6-Bis(benzyloxycarbonyl)-L-lysine N2,N6-Bis(benzyloxycarbonyl)lysine N2,N6-Bis[(benzyloxy)carbonyl]-L-lysine Nα,Nε-Bis(benzyloxycarbonyl)-L-lysine N,N'-Dibenzyloxycarbonyl-L-lysine N-alpha-N-epsilon-Bis-benzyloxycarbonyl-L-lysine Z-L-Lys(Z)-OH N-beta,epsilon-Bis-Z-L-lysine N,N'-(Dicarobenzyloxy)-L-lysine N2,N6-Bis[(phenylMethoxy)carbonyl]-L-lysine N2,N6-Dicarbobenzoxy-L-lysine NSC 88474 N2,N6-Bis-Cbz-L-lysine ZzLys[Z-Lys(Z)-OH] (S)-2,6-Bis(((benzyloxy)carbonyl)aMino)hexanoic acid Z-Lys(Z)-OH, 98%+ Z-Lys(Z)-OH >=98.0% (TLC) TIANFUCHEM--405-39-0--High purity Z-LYS(Z)-OH factory price Nα,ε-Bis-Z-L-lysine Z-LYS(Z)-OH USP/EP/BP (2S)-2,6-bis(phenylmethoxycarbonylamino)hexanoicaci (2S)-2,6-di{[(benzyloxy)carbonyl]amino}hexanoic acid (2S)-2,6-bis(phenylmethoxycarbonylamino)hexanoic acid Cbz-Lys(Z)-OH CBZ-LYS(CBZ)-OH Nα,Nε-Di-Z-L-lysine N2,N6-Dibenzyloxycarbonyl-L-lysin Z-Lys N,N'-Dibenzyloxycarbonyl-L-lysine 405-39-0 C6H5CH2O2CNHCH24CHNHCO2CH2C6H5CO2H CARBOXYLIC ACID Peptide Synthesis Specialty Synthesis Lysine Amino Acid Derivatives Amino Acid Derivatives