K-strophanthin-beta
- CAS No.
- 560-53-2
- Chemical Name:
- K-strophanthin-beta
- Synonyms
- Nsc4320;STROPHANTHIN;K-strophanthin-beta;.beta.-K-Strophanthin;Strophanthin K (crystalline);.beta.-Strophanthobioside, strophanthidin-3;3β-[(4-O-β-D-Glucopyranosyl-3-O-methyl-2,6-dideoxy-β-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxo-5β-card-20(22)-enolide;(3β,5β)-3-{[2,6-dideoxy-4-O-(β-D-glucopyranosyl)-3-O-methyl-β-D-ribo-hexopyranosyl]oxy}-5,14-dihydroxy-19-oxocard-20(22)-enolide;Card-20(22)-enolide, 3-[(2,6-dideoxy-4-O-β-D-glucopyranosyl-3-O-methyl-β-D-xylo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxo-, (3β,5β)-;5.beta.-Card-20(22)-enolide, 3.beta.-[(2,6-dideoxy-4-o-.beta.-D-glucopyranosyl-3-o-methyl-.beta.-D-ribo-hexopyranosyl)oxy]-5,14-dihydroxy-19-oxo-
- CBNumber:
- CB72130870
- Molecular Formula:
- C36H54O14
- Molecular Weight:
- 710.81
- MDL Number:
- MOL File:
- 560-53-2.mol
| Melting point | 195°C |
|---|---|
| Boiling point | 628.39°C (rough estimate) |
| Density | 1.1625 (rough estimate) |
| refractive index | 1.6130 (estimate) |
| pka | 12.89±0.70(Predicted) |
| FDA UNII | K935S3T1OE |
K-strophanthin-beta Chemical Properties,Uses,Production
Description
Strophanthin is made up of a mixture of glycosides, mainly K-strophanthin- β, 3β,5,14-trihydroxy-10-oxo-5β-card-20(22)-enolide-3-D-cymaro-β-D-glycoside, and K-strophanthoside, 3β,5,14-trihydroxy-10-oxo-5β-card-20(22)-enolide-3-Dcymaro- β-D-gluco-α-D-glycozide. It is isolated primarily from the family Strophantus kombe.
Uses
Strophanthin is used in severe cardiovascular insufficiency, in particular after myocardial infarction, for chronic cardiac insufficiency, cardiac decompensation, supraventricular tachycardia, and ventricular arrhythmia.
Definition
ChEBI: K-Strophanthin-beta is a cardenolide glycoside and a steroid aldehyde.