ChemicalBook >> CAS DataBase List >>2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride

2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride

CAS No.
42036-65-7
Chemical Name:
2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride
Synonyms
NSC 12467;NSC 620461;Tramadol EP Impurity E;Tramadol Impurity E HCl;Tramadol EP Impurity E HCl;TraMadol Related CoMpound B;TraMadol Hydrochloride IMpurity-E(EP);Tramadol stg-I mannich HCL EP imp-E RC-B;2-(DIMETHYLAMINOMETHYL) CYCLOHEXANONE HCL;2-(Dimethylaminomethyl)-1-cyclohexanoneHCl
CBNumber:
CB7214624
Molecular Formula:
C9H18ClNO
Molecular Weight:
191.7
MDL Number:
MFCD00102580
MOL File:
42036-65-7.mol
MSDS File:
SDS
Last updated:2024-06-12 10:29:45

2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride Properties

Melting point 147-151 °C
storage temp. 2-8°C
solubility Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form Crystalline Powder
color White
Water Solubility soluble
InChI InChI=1S/C9H17NO.ClH/c1-10(2)7-8-5-3-4-6-9(8)11;/h8H,3-7H2,1-2H3;1H
InChIKey CLVHTSWMNNSUSH-UHFFFAOYSA-N
SMILES C1(CN(C)C)CCCCC1=O.Cl
CAS DataBase Reference 42036-65-7(CAS DataBase Reference)
FDA UNII 9UU6LE6AUC

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
Signal word  Danger
Hazard statements  H315-H318-H335
Precautionary statements  P280-P305+P351+P338+P310
Safety Statements  24/25
HS Code  29223900

2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride price More Price(24)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich S935484 2-(DIMETHYLAMINOMETHYL)-1-CYCLOHEXANONE HYDROCHLORIDE Aldrich 42036-65-7 50mg $179 2024-03-01 Buy
Sigma-Aldrich 1672621 2-(DIMETHYLAMINOMETHYL)-1-CYCLOHEXANONE HYDROCHLORIDE United States Pharmacopeia (USP) Reference Standard 42036-65-7 25mg $1210 2024-03-01 Buy
TRC B585445 2-(Bismethyl)aminomethylcyclohexanoneHydrochloride 42036-65-7 2.5g $185 2021-12-16 Buy
Biosynth Carbosynth FD149699 2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride 42036-65-7 1g $200 2021-12-16 Buy
Biosynth Carbosynth FD149699 2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride 42036-65-7 2g $300 2021-12-16 Buy
Product number Packaging Price Buy
S935484 50mg $179 Buy
1672621 25mg $1210 Buy
B585445 2.5g $185 Buy
FD149699 1g $200 Buy
FD149699 2g $300 Buy

2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride Chemical Properties,Uses,Production

Chemical Properties

white crystalline powder

Uses

An impurity found in Tramadol (T712500).

Synthesis

0.982 g (1.03 mL, 10.0 mmol) cyclohexanone, 0.360 g (12.0 mmol) paraformaldehyde, 0.816 g (10.0 mmol) dimethylammonium chloride and 4 mL ethanol are filled in a 25 mL round bottom flask with reflux condenser and magnetic stir bar. 2 drops of conc. hydrochloric acid is added, and the mixture is heated under stirring for 4 hours under reflux. The hot solution is filtered in a round bottom flask, and the solvent is evaporated by the rotary evaporator. The residue is dissolved in 2 mL ethanol under heating. At room temperature, 20 mL acetone is added to the solution. For complete crystallization, the solution is stored overnight in the freezer compartment. The crystallized crude product 2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride is sucked off over a Buechner funnel and dried in the desiccator over silica gel.
2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride

2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 163)Suppliers
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Career Henan Chemica Co
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2-(DIMETHYLAMINOMETHYL)-1-CYCLOHEXANONE HYDROCHLORIDE 2-(DIMETHYLAMINOMETHYL)-CYCLOHEXAN-1-ONE HCL 2-(DIMETHYLAMINOMETHYL) CYCLOHEXANONE HCL 2-[(DIMETHYLAMINO)METHYL]CYCLOHEXANONE HYDROCHLORIDE 2-(N,N-DIMETHYLAMINOMETHYL)CYCLOHEXANONE HCL 2-(Dimethylaminomethyl)-1-cyclohexanone, hydrochloride salt 2-(Dimethylamino)methyl cyclhexanone hydrochloride 2-(Dimethylaminomethyl)-1-cyclohexanoneHCl 2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride 98% 2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride,98% 2-Dimethyl Amino Methyl Cyclohexanone.HCL (Menich Base) Tramadol Related Compound B (25 mg) (2-(dimethylaminomethyl)-1-cyclohexanone hydrochloride) 2-(DiMethylaMinoMethyl)-1-cyclohexanone hydrochlor 2-(DiMethylaMinoMethyl)-1-cyclohexanone hydrochloride, 98% 1GR 2-(BisMethyl)aMinoMethylcyclohexanone Hydrochloride DiMethyl((2-oxocyclohexyl)Methyl)aMMoniuM Chloride NSC 12467 NSC 620461 Cyclohexanone, 2-[(diMethylaMino)Methyl]-, hydrochloride TraMadol Hydrochloride IMpurity-E(EP) TraMadol Related CoMpound B Tramadol EP Impurity E Tramadol Impurity 5(Tramadol EP Impurity E) 2-dimethylaminomethyl cyclohexanon hydrochloride Tramadol Impurity E HCl Tramadol EP Impurity E HCl 2 - DIMETHYL - METHYL - 1 CYCLOHEXANONE HYDROCHLORIDE Tramadol stg-I mannich HCL EP imp-E RC-B Tramadol EP Impurity E/ Tramadol Related Compound B Tramadol Related Compound B (2-(dimethylaminomethyl)-1-cyclohexanone hydrochloride) (1672621) Tramadol USP Related Compound B as Hydrochloride Tramadol Hydrochloride EP Impurity E as Hydrochloride Tramadol EP Impurity E HCl (Tramadol USP Related Compound B) Tramadol Related Compound B (25 mg) (2-[(Dimethylamino)methyl]cyclohexanone hydrochloride) 42036-65-7 C9H17NOClH C9H17NOHCl Aminomethyl's Ring Systems