|
| 2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride Basic information |
Product Name: | 2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride | Synonyms: | 2-(DIMETHYLAMINOMETHYL)-1-CYCLOHEXANONE HYDROCHLORIDE;2-(DIMETHYLAMINOMETHYL)-CYCLOHEXAN-1-ONE HCL;2-(DIMETHYLAMINOMETHYL) CYCLOHEXANONE HCL;2-[(DIMETHYLAMINO)METHYL]CYCLOHEXANONE HYDROCHLORIDE;2-(N,N-DIMETHYLAMINOMETHYL)CYCLOHEXANONE HCL;2-(Dimethylaminomethyl)-1-cyclohexanone, hydrochloride salt;2-(Dimethylamino)methyl cyclhexanone hydrochloride;2-(Dimethylaminomethyl)-1-cyclohexanoneHCl | CAS: | 42036-65-7 | MF: | C9H18ClNO | MW: | 191.7 | EINECS: | | Product Categories: | Aminomethyl's;Ring Systems | Mol File: | 42036-65-7.mol | ![2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride Structure](CAS/GIF/42036-65-7.gif) |
| 2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride Chemical Properties |
Melting point | 147-151 °C | storage temp. | 2-8°C | solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | form | Crystalline Powder | color | White | Water Solubility | soluble | InChI | InChI=1S/C9H17NO.ClH/c1-10(2)7-8-5-3-4-6-9(8)11;/h8H,3-7H2,1-2H3;1H | InChIKey | CLVHTSWMNNSUSH-UHFFFAOYSA-N | SMILES | C1(CN(C)C)CCCCC1=O.Cl | CAS DataBase Reference | 42036-65-7(CAS DataBase Reference) |
Safety Statements | 24/25 | HS Code | 29223900 |
Provider | Language |
ACROS
| English |
| 2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride Usage And Synthesis |
Chemical Properties | white crystalline powder | Uses | An impurity found in Tramadol (T712500). | Synthesis |
0.982 g (1.03 mL, 10.0 mmol) cyclohexanone, 0.360 g (12.0 mmol) paraformaldehyde, 0.816 g (10.0 mmol) dimethylammonium chloride and 4 mL ethanol are filled in a 25 mL round bottom flask with reflux condenser and magnetic stir bar. 2 drops of conc. hydrochloric acid is added, and the mixture is heated under stirring for 4 hours under reflux. The hot solution is filtered in a round bottom flask, and the solvent is evaporated by the rotary evaporator. The residue is dissolved in 2 mL ethanol under heating. At room temperature, 20 mL acetone is added to the solution. For complete crystallization, the solution is stored overnight in the freezer compartment. The crystallized crude product 2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride is sucked off over a Buechner funnel and dried in the desiccator over silica gel.
|
| 2-(Dimethylaminomethyl)-1-cyclohexanone hydrochloride Preparation Products And Raw materials |
|