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UNOPROSTONE

CAS No.
120373-36-6
Chemical Name:
UNOPROSTONE
Synonyms
UNOPROSTONE;Unii-6X4F561V3w;Unoprostone [inn];Emorfazone Impurity 6;Alprostadil Impurity 20;13,14-DIHYDRO-15-KETO-20-ETHYL PROSTAGLANDIN F2ALPHA;9ALPHA, 11ALPHA-DIHYDROXY-15-OXO-20A,20B-DIHOMOPROST-5-EN-1-OIC ACID;(E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoic acid;5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-, (5Z)-
CBNumber:
CB7220472
Molecular Formula:
C22H38O5
Molecular Weight:
382.53
MDL Number:
MFCD00865635
MOL File:
120373-36-6.mol
Last updated:2023-06-08 09:02:17

UNOPROSTONE Properties

Boiling point 562.9±40.0 °C(Predicted)
Density 1.069±0.06 g/cm3(Predicted)
storage temp. Store at -20°C
solubility DMF: 25 mg/ml; DMSO: 17 mg/ml; Ethanol: 12 mg/ml; PBS (7.2): 90 μg/ml
pka 4.76±0.10(Predicted)
FDA UNII 6X4F561V3W
ATC code S01EE02

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Danger
Hazard statements  H360
NFPA 704
3
2 0

UNOPROSTONE price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 16680 Unoprostone ≥98% 120373-36-6 1mg $61 2024-03-01 Buy
Cayman Chemical 16680 Unoprostone ≥98% 120373-36-6 5mg $264 2024-03-01 Buy
Cayman Chemical 16680 Unoprostone ≥98% 120373-36-6 10mg $468 2024-03-01 Buy
Cayman Chemical 16680 Unoprostone ≥98% 120373-36-6 50mg $1862 2024-03-01 Buy
TRC U847060 Unoprostane 120373-36-6 5mg $210 2021-12-16 Buy
Product number Packaging Price Buy
16680 1mg $61 Buy
16680 5mg $264 Buy
16680 10mg $468 Buy
16680 50mg $1862 Buy
U847060 5mg $210 Buy

UNOPROSTONE Chemical Properties,Uses,Production

Uses

Unoprostane is a protectant against retinal degeneration in S334ter rhodopsin mutant rats. Neuroprotective agent.

Definition

ChEBI: Unoprostone is an oxo monocarboxylic acid, a prostaglandins Falpha and a ketone. It has a role as an antiglaucoma drug and an antihypertensive agent.

General Description

Unoprostone (Rescula) is supplied as a 0.15% sterileophthalmic solution. Unoprostone is somewhat unusual inthat it is a docosanoid (22-carbon atom) PGF analog marketedas the isopropyl ester. The natural 15-position alcoholis oxidized to the ketone as would be expected to occur invivo. Cautions and side effects are similar to those givenpreviously.

UNOPROSTONE Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 42)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
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AFINE CHEMICALS LIMITED
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Hefei Hirisun Pharmatech Co., Ltd
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Dayang Chem (Hangzhou) Co.,Ltd.
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LUYUNJIA CHEMISTRY XIAMEN LIMITED
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PT CHEM GROUP LIMITED
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GIHI CHEMICALS CO.,LIMITED
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China National Standard Pharmaceutical Corporation Limited
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Aladdin Scientific
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Xiamen Eagle Chemical Limited Corporation
+86-5925023701 +86-18900207489 yiyunchem@163.com China 6046 58
UNOPROSTONE 9ALPHA, 11ALPHA-DIHYDROXY-15-OXO-20A,20B-DIHOMOPROST-5-EN-1-OIC ACID Unii-6X4F561V3w Unoprostone [inn] 13,14-DIHYDRO-15-KETO-20-ETHYL PROSTAGLANDIN F2ALPHA (E)-7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-5-heptenoic acid 5-Heptenoic acid, 7-[(1R,2R,3R,5S)-3,5-dihydroxy-2-(3-oxodecyl)cyclopentyl]-, (5Z)- Alprostadil Impurity 20 Emorfazone Impurity 6 120373-36-6