Ethyl 4-piperidinecarboxylate
- CAS No.
- 1126-09-6
- Chemical Name:
- Ethyl 4-piperidinecarboxylate
- Synonyms
- ETHYL PIPERIDINE-4-CARBOXYLATE;ETHYL ISONIPECOTATE;4-piperidinecarboxylate;PIPERIDINE-4-CARBOXYLIC ACID ETHYL ESTER;H-Nip-OEt;H-DL-Inp-OEt;AKOS MSC-0737;RARECHEM AH CK 0180;TIMTEC-BB SBB004006;ETHYL ISONEPECOTATE
- CBNumber:
- CB7231962
- Molecular Formula:
- C8H15NO2
- Molecular Weight:
- 157.21
- MDL Number:
- MFCD00006003
- MOL File:
- 1126-09-6.mol
- MSDS File:
- SDS
Boiling point | 204 °C(lit.) |
---|---|
Density | 1.02 g/mL at 25 °C(lit.) |
vapor pressure | 39.4Pa at 25℃ |
refractive index |
n |
Flash point | 176 °F |
storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
form | Liquid |
pka | 9.83±0.10(Predicted) |
color | Clear colorless to slightly brown |
Water Solubility | miscible |
BRN | 118419 |
LogP | 1.15 |
CAS DataBase Reference | 1126-09-6(CAS DataBase Reference) |
NIST Chemistry Reference | Ethyl piperidine-4-carboxylate(1126-09-6) |
SAFETY
Risk and Safety Statements
Symbol(GHS) | ![]() GHS07 |
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Signal word | Warning | |||||||||
Hazard statements | H227-H315-H319-H335 | |||||||||
Precautionary statements | P210-P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P370+P378-P403+P235-P501-P210e-P261-P280a-P305+P351+P338-P405-P501a | |||||||||
Hazard Codes | C,Xi | |||||||||
Risk Statements | 34-36/37/38 | |||||||||
Safety Statements | 23-24/25-36-26 | |||||||||
RIDADR | UN2735 | |||||||||
WGK Germany | 3 | |||||||||
Hazard Note | Irritant | |||||||||
HS Code | 29333999 | |||||||||
NFPA 704 |
|
Ethyl 4-piperidinecarboxylate price More Price(27)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Sigma-Aldrich | E33505 | Ethyl isonipecotate 98% | 1126-09-6 | 25g | $51.3 | 2024-03-01 | Buy |
Sigma-Aldrich | E33505 | Ethyl isonipecotate 98% | 1126-09-6 | 100g | $148 | 2024-03-01 | Buy |
TCI Chemical | I0294 | Ethyl 4-Piperidinecarboxylate >98.0%(GC) | 1126-09-6 | 25mL | $36 | 2024-03-01 | Buy |
TCI Chemical | I0294 | Ethyl 4-Piperidinecarboxylate >98.0%(GC) | 1126-09-6 | 100mL | $94 | 2024-03-01 | Buy |
Alfa Aesar | B20601 | Ethyl isonipecotate, 98% | 1126-09-6 | 25g | $40.65 | 2024-03-01 | Buy |
Ethyl 4-piperidinecarboxylate Chemical Properties,Uses,Production
Chemical Properties
clear colorless to slightly brown liquid
Uses
Reactant for synthesis of:• ;SMN protein modulators1• ;β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition2• ;Nitroethylenediamines by nucleophilic ring opening of nitroimidazolidinone3• ;RhoA inhibitors for cardiovascular disease therapy4• ;Saccharin derived Mannich bases as antimicrobials and antioxidants5Reactant for one-pot reductive amination and Suzuki-Miyaura cross coupling of formyl aryl and heteroaryl MIDA boronates6
Uses
It is used as a reactant for synthesis of SMN protein modulators, β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition, nitroethylenediamines by nucleophilic ring opening of nitroimidazolidinone. It is also involved in the reactions of RhoA inhibitors for cardiovascular disease therapy and saccharin derived Mannich bases as antimicrobials and antioxidants. It is employed as a reactant for one-pot reductive amination and Suzuki-Miyaura cross coupling of formyl aryl and heteroaryl MIDA boronates.
Uses
Reactant for synthesis of SMN protein modulators and β-aryl and β-amino-substituted aliphatic esters by rhodium catalyzed tandem double bond migration/conjugate addition.
Synthesis Reference(s)
Tetrahedron Letters, 23, p. 193, 1982 DOI: 10.1016/S0040-4039(00)86783-0
Ethyl 4-piperidinecarboxylate Preparation Products And Raw materials
Raw materials
Preparation Products
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Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
Senova Technology Co. Ltd. | +86-0755-86703119 +8618503098836 | info@senovatech.com | China | 351 | 58 |
Shaanxi Dideu Medichem Co. Ltd | +86-29-81148696 +86-15536356810 | 1022@dideu.com | China | 3320 | 58 |
Anhui Yiao New Material Technology Co., Ltd | +86-18033737140 +86-17354101231 | sales1@hbganmiao.com | China | 253 | 58 |
Henan Fengda Chemical Co., Ltd | +86-371-86557731 +86-13613820652 | info@fdachem.com | China | 20294 | 58 |
Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 885 | 50 |
Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29798 | 60 |
Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21668 | 55 |
Shanghai Time Chemicals CO., Ltd. | +86-021-57951555 +8617317452075 | jack.li@time-chemicals.com | China | 1807 | 55 |
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
Zjartschem | +86-571 87238903 | jocelynpan@zjarts.com | CHINA | 993 | 58 |
View Lastest Price from Ethyl 4-piperidinecarboxylate manufacturers
Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
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2024-07-14 | Ethyl 4-piperidinecarboxylate
1126-09-6
|
US $0.10 / KG | 1KG | 98.0% | 10 | Shaanxi Dideu Medichem Co. Ltd | |
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2024-06-11 | Ethyl 4-piperidinecarboxylate
1126-09-6
|
US $0.00 / kg | 1kg | 99% | 1 ton | Anhui Yiao New Material Technology Co., Ltd | |
![]() |
2024-06-11 | Ethyl 4-piperidinecarboxylate
1126-09-6
|
US $0.00 / kg | 1kg | 99% | 1 ton | Anhui Yiao New Material Technology Co., Ltd |
-
- Ethyl 4-piperidinecarboxylate
1126-09-6
- US $0.10 / KG
- 98.0%
- Shaanxi Dideu Medichem Co. Ltd
-
- Ethyl 4-piperidinecarboxylate
1126-09-6
- US $0.00 / kg
- 99%
- Anhui Yiao New Material Technology Co., Ltd
-
- Ethyl 4-piperidinecarboxylate
1126-09-6
- US $0.00 / kg
- 99%
- Anhui Yiao New Material Technology Co., Ltd
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