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26,27-Dinorergost-5-ene-3β,24-diol

26,27-Dinorergost-5-ene-3β,24-diol structure

CAS No.: 35882-85-0

Chemical Name:: 26,27-Dinorergost-5-ene-3β,24-diol

Synonyms: SGE-201;SGE 201,SGE201;26,27-Dinorergost-5-ene-3β,24-diol;24,24-dimethyl-cholene-(5)-diol-(3β.24);26,27-Dinorergost-5-ene-3,24-diol, (3β)-;(3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-5-hydroxy-5-methylhexan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol

CBNumber:: CB72396838

Molecular Formula:: C26H44O2

Molecular Weight:: 388.63

MDL Number:: MFCD28386299

MOL File:: 35882-85-0.mol

Last updated:2024-10-28 16:48:35

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26,27-Dinorergost-5-ene-3β,24-diol Properties

Boiling point	501.1±23.0 °C(Predicted)
Density	1.04±0.1 g/cm3(Predicted)
pka	15.03±0.70(Predicted)

26,27-Dinorergost-5-ene-3β,24-diol Chemical Properties,Uses,Production

Description

SGE-201 is a potent allosteric modulator of N-methyl-D-aspartate receptors. SGE-201 is an analogue of an endogenous oxysterol. bSGE-201 increased the actions of memantine and ketamine on phasic excitatory post-synaptic currents, but neither revealed underlying pharmacodynamic differences. SGE-201 accelerated the re-equilibration of blockers during voltage jumps. SGE-201 also unmasked differences among the blockers in neuronal networks - measured either by suppression of activity in multi-electrode arrays or by neuroprotection against a mild excitotoxic insult.

26,27-Dinorergost-5-ene-3β,24-diol synthesis

Synthesis of 26,27-Dinorergost-5-ene-3β,24-diol from 3β-Acetoxychola-5-ene-24-oic acid methyl ester and Methylmagnesium chloride

26,27-Dinorergost-5-ene-3β,24-diol Preparation Products And Raw materials

Raw materials

Chol-5-en-24-oic acid, 3-hydroxy-, ethyl ester, (3β)- 3β-Acetoxychola-5-ene-24-oic acid methyl ester Methylmagnesium chloride Methyllithium

Preparation Products

26,27-Dinorergost-5-ene-3β,24-diol Suppliers

Global( 4)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
TargetMol Chemicals Inc.	+8613564774135	zijue.cai@tsbiochem.com	United States	19884	58
SPIRO PHARMA		eric_feng1954@126.com	China	9248	55
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	19703	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58
SPIRO PHARMA	55
TargetMol Chemicals Inc.	58

View Lastest Price from 26,27-Dinorergost-5-ene-3β,24-diol manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-10-28	SGE-201 35882-85-0	US $1980.00-1520.00 / mg			10g	TargetMol Chemicals Inc.

SGE-201
35882-85-0
US $1980.00-1520.00 / mg
TargetMol Chemicals Inc.

26,27-Dinorergost-5-ene-3β,24-diol SGE-201 24,24-dimethyl-cholene-(5)-diol-(3β.24) (3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-5-hydroxy-5-methylhexan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol SGE 201,SGE201 26,27-Dinorergost-5-ene-3,24-diol, (3β)- 35882-85-0