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Bardoxolone

Bardoxolone Structure
Bardoxolone structure
CAS No.
890707-28-5
Chemical Name:
Bardoxolone
Synonyms
2-Amino-5-chloro-N,3-dimethylbenzamide;cas 890707-28-5 98%;Bardoxolone Powder C9h11cln2o;cas 890707-28-5 Coragen intermediate;cas 890707-28-5 98% Coragen intermediate;Benzamide, 2-amino-5-chloro-N,3-dimethyl-;2-Amino-5-chloro-N,3-dimethylbenzamide 98%;2-Amino-5-chloro-N,3-dimethylbenzamide, 95+%
CBNumber:
CB72501263
Molecular Formula:
C9H11ClN2O
Molecular Weight:
198.65
MDL Number:
MFCD09030601
MOL File:
890707-28-5.mol
Last updated:2024-04-14 12:17:37
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Bardoxolone Properties

Melting point 130-132 °C
Boiling point 308.8±42.0 °C(Predicted)
Density 1.239
vapor pressure 0-0Pa at 20-25℃
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility Chloroform (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka 14.24±0.46(Predicted)
form Solid
color Off-White to Light Brown
InChI InChI=1S/C9H11ClN2O/c1-5-3-6(10)4-7(8(5)11)9(13)12-2/h3-4H,11H2,1-2H3,(H,12,13)
InChIKey WOBVZGBINMTNKL-UHFFFAOYSA-N
SMILES C(NC)(=O)C1=CC(Cl)=CC(C)=C1N
LogP 1.7 at 25℃
Surface tension 67.8mN/m at 249.3mg/L and 20.4℃
FDA UNII 7HT68L8941
NCI Drug Dictionary bardoxolone

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H312-H332
Precautionary statements  P280
HS Code  29242990

Bardoxolone price More Price(16)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Biosynth Carbosynth FA159371 2-Amino-5-chloro-N,3-dimethylbenzamide 890707-28-5 1g $60 2021-12-16 Buy
Biosynth Carbosynth FA159371 2-Amino-5-chloro-N,3-dimethylbenzamide 890707-28-5 2g $90 2021-12-16 Buy
Biosynth Carbosynth FA159371 2-Amino-5-chloro-N,3-dimethylbenzamide 890707-28-5 5G $120 2021-12-16 Buy
Biosynth Carbosynth FA159371 2-Amino-5-chloro-N,3-dimethylbenzamide 890707-28-5 10g $180 2021-12-16 Buy
Biosynth Carbosynth FA159371 2-Amino-5-chloro-N,3-dimethylbenzamide 890707-28-5 25g $250 2021-12-16 Buy
Product number Packaging Price Buy
FA159371 1g $60 Buy
FA159371 2g $90 Buy
FA159371 5G $120 Buy
FA159371 10g $180 Buy
FA159371 25g $250 Buy

Bardoxolone Chemical Properties,Uses,Production

Chemical Properties

Off-white powder

Uses

Bardoxolone is a synthetic oleanane triterpenoid that exerts multifunctional activities in the control of cellular growth and differentiation. Bardoxolone is capable of activating the transcription factor peroxisome proliferator activator receptor-γ (PPARγ), its apoptotic effects in malignant cells have been shown to occur independently of PPARγ. Bardoxolone was developed as an potential drug for the improvement of hyperglycemia, proteinuria, glomerulus structure, serum creatine, which may in turn be beneficial to treat diabetic kidney diseases, cancer and thromboembolic events.

Bardoxolone synthesis

870997-57-2
890707-28-5
Synthesis of Bardoxolone from Methyl 2-amino-3-methylbenzoate

Bardoxolone Preparation Products And Raw materials

Raw materials

2H-3,1-Benzoxazine-2,4(1H)-dione, 6-chloro-8-methyl- 2-Amino-5-chloro-3-methylbenzoic acid Methylamine 2-BROMO-4-CHLORO-6-METHYLANILINE Methyl 2-amino-3-methylbenzoate
Benzoic acid, 2-aMino-5-chloro-3-Methyl-, Methyl ester 2-(hydroxyimino)-N-(2-methylphenyl)acetamide 7-METHYL-1H-INDOLE-2,3-DIONE Methylamine hydrochloride carbon monoxide
3-Methylanthranilic acid o-Toluidine 3-Methyl-2-nitrobenzoic acid

1of3

Preparation Products

Bardoxolone Suppliers

Global( 158)Suppliers
Supplier Tel Email Country ProdList Advantage
Win-Win chemical CO., Limited 		+86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 14394 58
Capot Chemical Co.,Ltd. 		+86-（0）57185586718 +86-13336195806 sales@capot.com China 29791 60
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21634 55
Hangzhou FandaChem Co.,Ltd. 		+8615858145714 FandaChem@Gmail.com China 9214 55
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
CONIER CHEM AND PHARMA LIMITED 		+8618523575427 sales@conier.com China 49374 58
career henan chemical co 		+86-0371-86658258 +8613203830695 factory@coreychem.com China 29811 58
Zhengzhou Alfa Chemical Co.,Ltd 		+8618530059196 sale04@alfachem.cn China 13505 58
Hebei Mojin Biotechnology Co., Ltd 		+86 13288715578 +8613288715578 sales@hbmojin.com China 12840 58
SIMAGCHEM CORP 		+86-13806087780 sale@simagchem.com China 17365 58
Supplier Advantage
Win-Win chemical CO., Limited 		58
Capot Chemical Co.,Ltd. 		60
Henan Tianfu Chemical Co.,Ltd. 		55
Hangzhou FandaChem Co.,Ltd. 		55
Alchem Pharmtech,Inc. 		58
CONIER CHEM AND PHARMA LIMITED 		58
career henan chemical co 		58
Zhengzhou Alfa Chemical Co.,Ltd 		58
Hebei Mojin Biotechnology Co., Ltd 		58
SIMAGCHEM CORP 		58

View Lastest Price from Bardoxolone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Bardoxolone pictures 2023-01-31 Bardoxolone
890707-28-5
 US $100.00 / KG 1KG 99% 5000kg/week Hebei Mojin Biotechnology Co., Ltd
2-Amino-5-chloro-N,3-dimethylbenzamide pictures 2023-01-31 2-Amino-5-chloro-N,3-dimethylbenzamide
890707-28-5
 US $0.00 / KG 25KG 99.99% 200ton Hebei Mojin Biotechnology Co., Ltd
Bardoxolone Powder C9h11cln2o pictures 2023-01-31 Bardoxolone Powder C9h11cln2o
890707-28-5
 US $50.00 / KG 1KG 99% 20ton Hebei Mojin Biotechnology Co., Ltd
  • Bardoxolone pictures
  • Bardoxolone
    890707-28-5
  • US $100.00 / KG
  • 99%
  • Hebei Mojin Biotechnology Co., Ltd

890707-28-5(Bardoxolone)Related Search:

2-AMino-5-cyano-N,3-diMethylbenzaMide 2-Amino-5-chloro-3-methylbenzoic acid
2-Amino-5-chloro-N,3-dimethylbenzamide 98% Benzamide, 2-amino-5-chloro-N,3-dimethyl- Bardoxolone Powder C9h11cln2o cas 890707-28-5 98% cas 890707-28-5 Coragen intermediate cas 890707-28-5 98% Coragen intermediate 2-Amino-5-chloro-N,3-dimethylbenzamide 2-Amino-5-chloro-N,3-dimethylbenzamide, 95+% 890707-28-5