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Bortezomib intermediates II

CAS No.
205393-21-1
Chemical Name:
Bortezomib intermediates II
Synonyms
Atrazine Impurity 11;Bortezomib intermediates I;Bortezomib Impurity 54 HCl;BortezoMib InterMediate II;Bortezomib intermediates II;BortezoMib interMediates N-2;(S)-2-amino-N-((R)-3-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)-3-phenylpropanamide hydrochloride;(αS)-α-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-benzenepropanamide Monohydrochloride;(αS)-α-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-benzenepropanamide Monohydrochloride;(alphaS)-alpha-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]benzenepropanamide hydrochloride
CBNumber:
CB72505953
Molecular Formula:
C24H38BClN2O3
Molecular Weight:
448.83412
MDL Number:
MFCD18252917
MOL File:
205393-21-1.mol
Last updated:2022-08-26 12:16:43

Bortezomib intermediates II Properties

Melting point 197-198℃
storage temp. Inert atmosphere,Store in freezer, under -20°C

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS05
Signal word  Warning
Hazard statements  H290-H314
Precautionary statements  P264b-P271-P280-P301+P330+P331-P304+P340-P305+P351+P338-P310-P363-P390-P402-P403+P233-P406b-P501c

Bortezomib intermediates II price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC A609965 (αS)-α-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-benzenepropanamideMonohydrochloride 205393-21-1 100mg $1540 2021-12-16 Buy
Biosynth Carbosynth FA151451 (alphaS)-alpha-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]benzenepropanamideHydrochloride 205393-21-1 25mg $405 2021-12-16 Buy
AK Scientific 5650EA BortezomibintermediatesII 205393-21-1 25mg $596 2021-12-16 Buy
Biosynth Carbosynth FA151451 (alphaS)-alpha-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]benzenepropanamideHydrochloride 205393-21-1 50mg $704 2021-12-16 Buy
Biosynth Carbosynth FA151451 (alphaS)-alpha-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]benzenepropanamideHydrochloride 205393-21-1 2mg $59 2021-12-16 Buy
Product number Packaging Price Buy
A609965 100mg $1540 Buy
FA151451 25mg $405 Buy
5650EA 25mg $596 Buy
FA151451 50mg $704 Buy
FA151451 2mg $59 Buy

Bortezomib intermediates II Chemical Properties,Uses,Production

Uses

(αS)-α-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-benzenepropanamide Monohydrochloride is a Bortezomib (B675700) intermediate which is used in the evaluation of bone-targeted proteasome inhibitors for myeloma.

Bortezomib intermediates II Preparation Products And Raw materials

Raw materials

Preparation Products

Bortezomib intermediates II Suppliers

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CONIER CHEM AND PHARMA LIMITED
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Bortezomib intermediates II (alphaS)-alpha-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]benzenepropanamide hydrochloride BortezoMib InterMediate II BortezoMib interMediates N-2 (αS)-α-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-benzenepropanamide Monohydrochloride Bortezomib intermediates I BenzenepropanaMide, a-aMino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-triMethyl-4,6-Methano-1,3,2-benzodioxaborol-2-yl]-3-Methylbutyl]-, hydrochloride (1:1), (aS) (αS)-α-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]-benzenepropanamide Monohydrochloride (S)-2-amino-N-((R)-3-methyl-1-((3aS,4S,6S,7aR)-3a,5,5-trimethylhexahydro-4,6-methanobenzo[d][1,3,2]dioxaborol-2-yl)butyl)-3-phenylpropanamide hydrochloride Bortezomib Impurity 54 HCl (alphaS)-alpha-Amino-N-[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]benzenepropanamide Hydrochloride (Bortezomib Intermediate II) Atrazine Impurity 11 205393-21-1 C24H37BN2O3HCl C24H38BClN2O3 C24H37BN2O3ClH