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ChemicalBook >> CAS DataBase List >>(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate

(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate

(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate Structure
(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate structure
CAS No.
1187479-72-6
Chemical Name:
(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate
Synonyms
Bortezomib Impurity 53;(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate;tert-butyl 4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)-benzoyl)piperazin-1-carboxylate;Carbamic acid, N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-, 1,1-dimethylethyl ester
CBNumber:
CB92735156
Molecular Formula:
C29H45BN2O5
Molecular Weight:
512.49
MDL Number:
MFCD18207137
MOL File:
1187479-72-6.mol
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(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate Properties

Boiling point 635.7±55.0 °C(Predicted)
Density 1.10±0.1 g/cm3(Predicted)
pka 11.39±0.46(Predicted)

(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC H294360 N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-CarbamicAcid1,1-DimethylethylEster 1187479-72-6 25mg $195 2021-12-16 Buy
Product number Packaging Price Buy
H294360 25mg $195 Buy

(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate Chemical Properties,Uses,Production

Uses

N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-Carbamic Acid 1,1-Dimethylethyl Ester is an intermediate in the synthesis of bortezomib (B675700).Bortezomib is the first proteasome inhibitor to be approved by the US FDA for multiple myeloma, a blood cancer.

(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate Preparation Products And Raw materials

Raw materials

Preparation Products

(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate Suppliers

Global( 11)Suppliers
Supplier Tel Email Country ProdList Advantage
Alputon Inc. 021-60753308-14013 China 137 55
Shenzhen ruikai de biotechnology co., ltd. 0755-61348847 17820674378 2682116078@qq.com China 7844 58
Meng Cheng Technology (Shanghai) Co., LTD 400-820-6829 sales@mitachieve.com China 8864 58
Energy Chemical 021-58432009 400-005-6266 marketing1@energy-chemical.com China 44843 58
Hubei Ruinuo Pharmaceutical Technology Co., Ltd 13165688766 3008058303@qq.com China 5000 58
Chengdu Bochen Chuangke Biomedical Technology Co., Ltd. 13550099873 307211881@qq.com China 125 58
Molcoo Chemicals Inc. 18627923403 18627753421 3001006472@qq.com China 9184 58
Shanghai Zerui Biotechnology Co., Ltd. 021-54580889 18321124657 731997554@qq.com China 10614 58
Hubei Moco Chemical Co., Ltd. 18627753421 17386083646 3001009495@qq.com China 10896 58
Supplier Advantage
Alputon Inc. 55
Shenzhen ruikai de biotechnology co., ltd. 58
Meng Cheng Technology (Shanghai) Co., LTD 58
Energy Chemical 58
Hubei Ruinuo Pharmaceutical Technology Co., Ltd 58
Chengdu Bochen Chuangke Biomedical Technology Co., Ltd. 58
Molcoo Chemicals Inc. 58
Shanghai Zerui Biotechnology Co., Ltd. 58
Hubei Moco Chemical Co., Ltd. 58

1187479-72-6((1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate)Related Search:

Isovaleraldehyde Bortezomib Impurity 8 4,6-Methano-1,3,2-benzodioxaborole,2-[(1S)-1-chloro-3-Methylbutyl]hexahydro-3a,5,5-triMethyl-,(3aS,4S,6S,7aR)- Bortezomib Impurity 57 (R)-3-phenyl-2-(pyrazine-2-carboxaMido)propanoic acid
BORTEZOMIB-PINANEDIOL Bortezomib intermediates II 3,6-Dibenzylhexahydropyrazine-2,5-dione Bortezomib Impurity 52 Bortezomib Impurity 9
Desisobutyl-n-butyl BortezoMib (IS,2S,3R,5S)-Pinanediol-L-phenylalanine-L-leucine boronate, HCl salt (S,E)-N-(1-((3-methylbut-1-en-1-yl)amino)-1-oxo-3-phenylpropan-2-yl) pyrazine-2-carboxamide Bortezomib Impurity 32 (S)-(+)-PINANEDIOL (DICHLORMETHYL)BORONATE
Bortezomib Impurity 47 HCl Bortezomib Impurity 60 4,6-Methano-1,3,2-benzodioxaborole-2-methanamine

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(1S,2S,3R,5S)-PinanediolN-BOC-L-phenylalanine-L-leucine boronate tert-butyl 4-(2-fluoro-5-((4-oxo-3,4-dihydrophthalazin-1-yl)Methyl)-benzoyl)piperazin-1-carboxylate Bortezomib Impurity 53 Carbamic acid, N-[(1S)-2-[[(1R)-1-[(3aS,4S,6S,7aR)-hexahydro-3a,5,5-trimethyl-4,6-methano-1,3,2-benzodioxaborol-2-yl]-3-methylbutyl]amino]-2-oxo-1-(phenylmethyl)ethyl]-, 1,1-dimethylethyl ester 1187479-72-6