ChemicalBook >> CAS DataBase List >>5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine

5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine

5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine structure

CAS No.: 865362-74-9

Chemical Name:: 5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine

Synonyms: CS-1137;FR 180204;FR-0180204;LM-3319 FR 180204;ERK Inhibitor II, FR180204;FR 180204;FR-180204;FR180204;ERK Inhibitor II, FR180204 - CAS 865362-74-9 - Calbiochem;FR 180204, 98%, a potent and selective ATP-competitive inhibitor of ERK;5-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine;1H-Pyrazolo[3,4-c]pyridazin-3-amine, 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)-

CBNumber:: CB72518957

Molecular Formula:: C18H13N7

Molecular Weight:: 327.34

MDL Number:: MFCD14585805

MOL File:: 865362-74-9.mol

MSDS File:: SDS

Last updated:2024-10-31 18:15:48

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5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine Properties

Melting point	267 °C
Density	1.55±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	DMSO: ≥10mg/mL
pka	7.19±0.50(Predicted)
form	Yellow solid
color	faint yellow to dark yellow
FDA UNII	4C7X7GV82C

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H302

Precautionary statements

P264-P270-P301+P312-P330-P501

Hazard Codes

Risk Statements

22-20

Safety Statements

20/21

WGK Germany

HS Code

29339900

NFPA 704

	0
2		0

5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine price More Price(40)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML0320	FR 180204 ≥98% (HPLC)	865362-74-9	5mg	$158	2024-03-01	Buy
Sigma-Aldrich	328007	ERK Inhibitor II, FR180204	865362-74-9	1mg	$195.17	2021-12-16	Buy
TCI Chemical	F1214	FR 180204	865362-74-9	5MG	$118	2024-03-01	Buy
TCI Chemical	F1214	FR 180204	865362-74-9	25MG	$420	2024-03-01	Buy
Cayman Chemical	15544	FR 180204 ≥98%	865362-74-9	1mg	$62	2024-03-01	Buy

Product number	Packaging	Price	Buy
SML0320	5mg	$158	Buy
328007	1mg	$195.17	Buy
F1214	5MG	$118	Buy
F1214	25MG	$420	Buy
15544	1mg	$62	Buy

5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine Chemical Properties,Uses,Production

Uses

FR180204 has been used as ERK inhibitor:

to block extracellular-signal-regulated kinase (ERK) in order to validate whether homeobox B7 (HOXB7) regulates the migration and proliferation process via AKT/mitogen-activated protein kinases (MAPK) signaling
of extracellular-signal-regulated kinase (ERK) to study the effects of signaling pathway inhibitors on differentiation and cell traction stress
to determine if phosphorylation of this signaling protein is essential for mesenchymal stromal cell (MSC) derived therapeutic efficacy

Definition

ChEBI: 5-(2-phenyl-3-pyrazolo[1,5-a]pyridinyl)-2H-pyrazolo[3,4-c]pyridazin-3-amine is a member of pyrazoles and a ring assembly.

Biochem/physiol Actions

FR180204 is a potent, cell-permeable, ATP-competitive inhibitor of ERK1 and ERK2 (mitogen-activated protein kinase (MAPK)/extracellular-signal-regulated kinases (ERK) 1/2).

storage

Store at +4°C

5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine Preparation Products And Raw materials

Raw materials

Preparation Products

5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine Suppliers

Global( 89)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32820	60
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22963	58
career henan chemical co	+86-0371-86658258 +8613203830695	factory@coreychem.com	China	29815	58
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32038	58
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	23325	58
Zhejiang J&C Biological Technology Co.,Limited	+1-2135480471 +1-2135480471	sales@sarms4muscle.com	China	10473	58
InvivoChem	+1-708-310-1919 +1-13798911105	sales@invivochem.cn	United States	6391	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	13417589054	trendseenbio@gmail.com	China	11681	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8467	58
LEAPCHEM CO., LTD.	+86-852-30606658	market18@leapchem.com	China	43340	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
Hubei xin bonus chemical co. LTD	58
career henan chemical co	58
TargetMol Chemicals Inc.	58
Dideu Industries Group Limited	58
Zhejiang J&C Biological Technology Co.,Limited	58
InvivoChem	58
ShenZhen Trendseen Biological Technology Co.,Ltd.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
LEAPCHEM CO., LTD.	58

View Lastest Price from 5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-10-31	FR 180204 865362-74-9	US $36.00-78.00 / mg		99.8%	10g	TargetMol Chemicals Inc.
	2019-12-23	5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine 865362-74-9	US $1.00 / KG	1KG	99%	100KG	Career Henan Chemical Co

FR 180204
865362-74-9
US $36.00-78.00 / mg
99.8%
TargetMol Chemicals Inc.

5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine
865362-74-9
US $1.00 / KG
99%
Career Henan Chemical Co

5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine Spectrum

5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine(865362-74-9)¹HNMR

865362-74-9(5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine)Related Search:

MK-2206 2HCl 1,9-Pyrazoloanthrone SB 203580 SCH772984 LY 294002 HYDROCHLORIDE

5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine LM-3319 FR 180204 FR 180204 1H-Pyrazolo[3,4-c]pyridazin-3-amine, 5-(2-phenylpyrazolo[1,5-a]pyridin-3-yl)- 5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine FR 180204 5-(2-Phenylpyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-amine ERK Inhibitor II, FR180204 FR 180204, 98%, a potent and selective ATP-competitive inhibitor of ERK FR 180204;FR-180204;FR180204 CS-1137 ERK Inhibitor II, FR180204 - CAS 865362-74-9 - Calbiochem 5-(2-Phenyl-pyrazolo[1,5-a]pyridin-3-yl)-1H-pyrazolo[3,4-c]pyridazin-3-ylamine USP/EP/BP Apoptosis,Extracellular signal regulated kinases,FR-180204,Inhibitor,inhibit,ERK,FR 180204 FR-0180204 865362-74-9 Inhibitors