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TTT-3002

TTT-3002 structure

CAS No.: 871037-95-5

Chemical Name:: TTT-3002

Synonyms: TTT-3002;9,12-Epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxamide, 10-amino-2,3,9,10,11,12-hexahydro-N,9-dimethyl-1-oxo-, (9S,10R,12R)-

CBNumber:: CB72731154

Molecular Formula:: C27H23N5O3

Molecular Weight:: 465.50322

MDL Number:

MOL File:: 871037-95-5.mol

Last updated:2023-03-31 09:12:59

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TTT-3002 Properties

Boiling point	770.4±60.0 °C(Predicted)
Density	1.68±0.1 g/cm3(Predicted)
pka	14.18±0.60(Predicted)

TTT-3002 Chemical Properties,Uses,Production

Description

TTT-3002 is a tyrosine kinase inhibitor (TKI) that is one of the most potent FLT3 inhibitors discovered to date. Studies using human FLT3/ITD mutant leukemia cell lines revealed the half maximal inhibitory concentration (IC50) for inhibiting FLT3 autophosphorylation is from 100 to 250 pM. The proliferation IC50 for TTT-3002 in these same cells was from 490 to 920 pM. TTT-3002 also showed potent activity when tested against the most frequently occurring FLT3-activating point mutation, FLT3/D835Y, against which many current TKIs are ineffective.

TTT-3002 Preparation Products And Raw materials

Raw materials

Preparation Products

TTT-3002 Suppliers

Global( 1)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	15002134094	marketing@targetmol.cn	China	19696	58

Supplier	Advantage
TargetMol Chemicals Inc.	58

TTT-3002 9,12-Epoxy-1H-diindolo[1,2,3-fg:3',2',1'-kl]pyrrolo[3,4-i][1,6]benzodiazocine-10-carboxamide, 10-amino-2,3,9,10,11,12-hexahydro-N,9-dimethyl-1-oxo-, (9S,10R,12R)- 871037-95-5