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1-TRIMETHYLSILYLMETHANOL

CAS No.
3219-63-4
Chemical Name:
1-TRIMETHYLSILYLMETHANOL
Synonyms
DK264;NSC 96777;rimethylsilylmethanol;(trimethylsilyl)-methano;1-TRIMETHYLSILYLMETHANOL;(TRIMETHYLSILYL)METHANOL;Methanol, (trimethylsilyl)-;TRIMETHYLHYDROXYMETHYLSILANE;Methanol,1-(trimethylsilyl)-;1-TRIMETHYLSILYLMETHANOL, 98+%
CBNumber:
CB7284458
Molecular Formula:
C4H12OSi
Molecular Weight:
104.22
MDL Number:
MFCD00004596
MOL File:
3219-63-4.mol
MSDS File:
SDS
Last updated:2024-12-18 14:15:30

1-TRIMETHYLSILYLMETHANOL Properties

Melting point <0°C
Boiling point 120-122 °C754 mm Hg(lit.)
Density 0.826 g/mL at 25 °C(lit.)
refractive index n20/D 1.419(lit.)
Flash point 88 °F
storage temp. 2-8°C
pka 15.92±0.10(Predicted)
form clear liquid
color Colorless to Almost colorless
Specific Gravity 0.827
Water Solubility Fully miscible in water.
Hydrolytic Sensitivity 1: no significant reaction with aqueous systems
BRN 1731486
CAS DataBase Reference 3219-63-4(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII E19993083K
EPA Substance Registry System Methanol, (trimethylsilyl)- (3219-63-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS02,GHS07
Signal word  Warning
Hazard statements  H226-H315-H319-H335
Precautionary statements  P261-P305+P351+P338-P210-P240-P241-P280a-P303+P361+P353-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36
RIDADR  UN 1987 3/PG 3
WGK Germany  3
RTECS  PC4100000
TSCA  Yes
HS Code  2931.90.9010
HazardClass  3
PackingGroup  III
NFPA 704
2
0 0

1-TRIMETHYLSILYLMETHANOL price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TCI Chemical T1250 Trimethylsilylmethanol >97.0%(GC) 3219-63-4 5mL $113 2024-03-01 Buy
TCI Chemical T1250 Trimethylsilylmethanol >97.0%(GC) 3219-63-4 25mL $389 2024-03-01 Buy
Alfa Aesar L04251 1-Trimethylsilylmethanol, 95% 3219-63-4 1g $37.65 2024-03-01 Buy
Alfa Aesar L04251 1-Trimethylsilylmethanol, 95% 3219-63-4 5g $156.65 2024-03-01 Buy
Usbiological 291767 Trimethylsilylmethanol 3219-63-4 2g $313 2021-12-16 Buy
Product number Packaging Price Buy
T1250 5mL $113 Buy
T1250 25mL $389 Buy
L04251 1g $37.65 Buy
L04251 5g $156.65 Buy
291767 2g $313 Buy

1-TRIMETHYLSILYLMETHANOL Chemical Properties,Uses,Production

Uses

1-Trimethylsilylmethanol is used as nucleophile to resolve the racemate obtained from enantioselective esterification of naproxen (2-(6-methoxy-2-naphthyl) propionic acid) by lipases. It was also used as a nucleophilic hydroxymethylation agent.

Purification Methods

If the NMR indicates impurities (should have only two signals), then dissolve it in Et2O, shake this with aqueous 5N NaOH, M H2SO4, saturated aqueous NaCl, dry (MgSO4) and distil it using an efficient column at atmospheric pressure. The 3,5-dinitrobenzoate has m 70-70.5o (from 95% EtOH). [Huang & Wang Acta Chem Sin 23 291 1957, cf. Chem Abstr 52 19911 1958, Speier et al. J Am Chem Soc 81 1844 1959 and Speier et al. J Am Chem Soc 70 1117 1948, Beilstein 4 III 1844, 4 IV 2876.]

1-TRIMETHYLSILYLMETHANOL Preparation Products And Raw materials

Global( 140)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co.,Ltd
+86-15028179902 angelia@hbmojin.com China 1176 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 18751 58
Hangzhou FandaChem Co.,Ltd.
+8615858145714 FandaChem@Gmail.com China 9087 55
ATK CHEMICAL COMPANY LIMITED
+undefined-21-51877795 ivan@atkchemical.com China 32957 60
Alchem Pharmtech,Inc.
8485655694 sales@alchempharmtech.com United States 63687 58
career henan chemical co
+86-0371-86658258 +8613203830695 factory@coreychem.com China 29811 58
Hubei Co-Formula Material Tech Co., Ltd.
+86-27-84459282 sales@cfmats.com CHINA 882 58
SIMAGCHEM CORP
+86-13806087780 sale@simagchem.com China 17365 58
Hefei TNJ Chemical Industry Co.,Ltd.
+86-0551-65418671 +8618949823763 sales@tnjchem.com China 34563 58
Win-Win chemical CO., Limited
+86-0086-577-64498589 +86-15355981851 sales@win-winchemical.com China 14426 58

View Lastest Price from 1-TRIMETHYLSILYLMETHANOL manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-TRIMETHYLSILYLMETHANOL pictures 2024-08-14 1-TRIMETHYLSILYLMETHANOL
3219-63-4
US $0.00 / kg 1kg 99% 50000KG/month Hebei Mojin Biotechnology Co.,Ltd
1-TRIMETHYLSILYLMETHANOL pictures 2019-12-20 1-TRIMETHYLSILYLMETHANOL
3219-63-4
US $1.00 / KG 1KG 99% KG/T Career Henan Chemical Co
(hydroxymethyl)trimethyl-silan (trimethylsilyl)-methano Methanol, (trimethylsilyl)- Silane, (hydroxymethyl)trimethyl- TRIMETHYLHYDROXYMETHYLSILANE (TRIMETHYLSILYL)METHANOL 1-TRIMETHYLSILYLMETHANOL (HYDROXYMETHYL)TRIMETHYLSILANE 1-TRIMETHYLSILYLMETHANOL, 98+% (Trimethylsilyl)methanol,(Hydroxymethyl)trimethylsilane NSC 96777 Methanol,1-(trimethylsilyl)- rimethylsilylmethanol DK264 3219-63-4 C4H12OSi CH33SiCH2OH Alcohols Building Blocks C2 to C6 Organic Building Blocks Oxygen Compounds Silicon Compounds (for Synthesis) Si (Classes of Silicon Compounds) Si-(C)4 Compounds Si (Classes of Silicon Compounds) Si-(C)4 Compounds Silicon Compounds (for Synthesis) Synthetic Organic Chemistry