ANTI-AMYLOID PRECURSOR PROTEIN
- CAS No.
- Chemical Name:
- ANTI-AMYLOID PRECURSOR PROTEIN
- Synonyms
- ANTI-APP;Anti-A11;ANTI-APP, HUMAN;Anti-Amyloid Oligomer αβ;Anti-Amyloid Oligomers (A11);ANTI-AMYLOID PRECURSOR PROTEIN;ANTI-AMYLOID PROTEIN PRECURSOR;Anti-AAA antibody produced in rabbit;Anti-AD1 antibody produced in rabbit;Anti-APP antibody produced in rabbit
- CBNumber:
- CB7292684
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00164640
- MOL File:
- Mol file
ANTI-AMYLOID PRECURSOR PROTEIN price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SAB4300464 | Anti-APP (Ab-668) antibody produced in rabbit affinity isolated antibody | 100μG | $441 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB4300153 | Anti-phospho-APP (p668) antibody produced in rabbit affinity isolated antibody | 100μG | $511 | 2024-03-01 | Buy | |
| Sigma-Aldrich | SAB3500274 | Anti-APP antibody produced in rabbit affinity isolated antibody, buffered aqueous solution | 100μG | $528 | 2024-03-01 | Buy | |
| Sigma-Aldrich | A8717 | Anti-Amyloid Precursor Protein, C-Terminal antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 25μL | $174 | 2024-03-01 | Buy | |
| Sigma-Aldrich | A8717 | Anti-Amyloid Precursor Protein, C-Terminal antibody produced in rabbit IgG fraction of antiserum, buffered aqueous solution | 100μL | $499 | 2024-03-01 | Buy |
ANTI-AMYLOID PRECURSOR PROTEIN Chemical Properties,Uses,Production
Uses
Applications in which this antibody has been used successfully, and the associated peer-reviewed papers, are given below.
Immunofluorescence (1 paper)
Uses
SH-SY5Y cell lysates were analyzed by western blot using rabbit anti-Amyloid Precursor Protein, C-Terminal as the primary antibody at a 1:500 dilution.
General Description
Amyloid precursor proteins (APPs) are transmembrane glycoproteins that are found in a wide range of tissues. APPs have 3 main isoforms, namely, APP695, APP751 and APP770 that are derived from alternative splicing events in cells. It is expressed at high levels in the brain. APP gene is mapped to human chromosome 21q11.2-q21. It is a 695 amino acid protein which possesses a large ectodomain and comparatively short intracellular region.
Biochem/physiol Actions
Amyloid precursor proteins (APPs) regulates cell growth, motility, neurite outgrowth and cell survival. The intracellular C-terminus of APP serves as a transcriptional regulator and as a receptor for kinesin-1-mediated axonal transport. Alzheimer′s disease is characterized by deposition of amyloid in the central nervous system, in neurite plaques and on cerebral vasculature. Mutations in the APP gene are linked with rare forms of autosomal dominant familial Alzheimer′s Disease (FAD). APPs undergo post-translational processing including N- and O-glycosylation, phosphorylation and sulfation.
ANTI-AMYLOID PRECURSOR PROTEIN Preparation Products And Raw materials
Raw materials
Preparation Products
ANTI-AMYLOID PRECURSOR PROTEIN Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Suzhou Ruinuode Biotechnology Co., Ltd. | -- | 2090855807@qq.com | CHINA | 6063 | 58 |
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| Beijing Fubo Biotechnology Co., Ltd. | -- | info@f-biology.com | CHINA | 6039 | 58 |
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| Shanghai Yubo Biotechnology Co., Ltd. | -- | shybio@126.com | CHINA | 6969 | 58 |
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