ANTI-AMYLOID PRECURSOR PROTEIN

ANTI-AMYLOID PRECURSOR PROTEIN 구조식 이미지
카스 번호:
상품명:
ANTI-AMYLOID PRECURSOR PROTEIN
동의어(영문):
ANTI-APP;Anti-A11;ANTI-APP, HUMAN;Anti-Amyloid Oligomer αβ;Anti-Amyloid Oligomers (A11);ANTI-AMYLOID PRECURSOR PROTEIN;ANTI-AMYLOID PROTEIN PRECURSOR;Anti-AAA antibody produced in rabbit;Anti-AD1 antibody produced in rabbit;Anti-APP antibody produced in rabbit
CBNumber:
CB7292684
분자식:
포뮬러 무게:
0
MOL 파일:
Mol file

ANTI-AMYLOID PRECURSOR PROTEIN 속성

저장 조건
-20°C

안전

위험품 표기 Xn
위험 카페고리 넘버 21/22
안전지침서 36/37

ANTI-AMYLOID PRECURSOR PROTEIN C화학적 특성, 용도, 생산

용도

SH-SY5Y cell lysates were analyzed by western blot using rabbit anti-Amyloid Precursor Protein, C-Terminal as the primary antibody at a 1:500 dilution.

일반 설명

Amyloid precursor proteins (APPs) are transmembrane glycoproteins that are found in a wide range of tissues. APPs have 3 main isoforms, namely, APP695, APP751 and APP770 that are derived from alternative splicing events in cells. It is expressed at high levels in the brain. APP gene is mapped to human chromosome 21q11.2-q21. It is a 695 amino acid protein which possesses a large ectodomain and comparatively short intracellular region.

Biochem/physiol Actions

Amyloid precursor proteins (APPs) regulates cell growth, motility, neurite outgrowth and cell survival. The intracellular C-terminus of APP serves as a transcriptional regulator and as a receptor for kinesin-1-mediated axonal transport. Alzheimer′s disease is characterized by deposition of amyloid in the central nervous system, in neurite plaques and on cerebral vasculature. Mutations in the APP gene are linked with rare forms of autosomal dominant familial Alzheimer′s Disease (FAD). APPs undergo post-translational processing including N- and O-glycosylation, phosphorylation and sulfation.

ANTI-AMYLOID PRECURSOR PROTEIN 준비 용품 및 원자재

원자재

준비 용품


ANTI-AMYLOID PRECURSOR PROTEIN 공급 업체

글로벌( 31)공급 업체
공급자 전화 이메일 국가 제품 수 이점
Suzhou Ruinuode Biotechnology Co., Ltd. --
2090855807@qq.com CHINA 6063 58
Shenzhen Xinbosheng Biological Technology Co., Ltd. --
service@neobioscience.com CHINA 6151 58
Shanghai Hao Biological Technology Co., Ltd. --
shxiyuanbio@163.com CHINA 6906 58
Shanghai Ziqi Biological Technology Co., Ltd. --
2453006496@qq.com CHINA 6184 58
Beijing Dongge Boye Biotechnology Co., Ltd. --
1861586486@qq.com CHINA 6648 58
Beijing Bi Orange Blue Biotechnology Co., Ltd. --
bo49855987@163.com CHINA 6827 58
Beijing Fubo Biotechnology Co., Ltd. --
info@f-biology.com CHINA 6025 58
Beijing Bai Ao Si Biotechnology Co., Ltd. --
yangmei@bioneeds.net CHINA 6999 58
Shanghai Yubo Biotechnology Co., Ltd. --
shybio@126.com CHINA 6967 58
Shanghai Hao Biological Technology Co., Ltd. --
market@xlswkj.com CHINA 6793 58

Copyright 2019 © ChemicalBook. All rights reserved