PK7242 Maleate
- CAS No.
- 1446352-68-6
- Chemical Name:
- PK7242 Maleate
- Synonyms
- PK7242 Maleate;2-[4-(4-fluorophenyl)-3-pyrrol-1-ylpyrazol-1-yl]-N,N-dimethylethanamine;2-[4-(4-Fluorophenyl)-3-(1-pyrrolyl)-1-pyrazolyl]-N,N-dimethylethanamine;1H-Pyrazole-1-ethanamine, 4-(4-fluorophenyl)-N,N-dimethyl-3-(1H-pyrrol-1-yl)-;2-(4-(4-fluorophenyl)-3-(1H-pyrrol-1-yl)-1H-pyrazol-1-yl)-N,N-dimethylethanamine
- CBNumber:
- CB73067571
- Molecular Formula:
- C17H19FN4
- Molecular Weight:
- 298.36
- MDL Number:
- MFCD29770812
- MOL File:
- 1446352-68-6.mol
PK7242 Maleate price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Cayman Chemical | 17230 | PK7242 (maleate) | 1446352-68-6 | 1mg | $107 | 2024-03-01 | Buy |
| Cayman Chemical | 17230 | PK7242 (maleate) | 1446352-68-6 | 5mg | $412 | 2024-03-01 | Buy |
| Cayman Chemical | 17230 | PK7242 (maleate) | 1446352-68-6 | 500μg | $57 | 2024-03-01 | Buy |
| AK Scientific | SYN5448 | PK7242Maleate | 1446352-68-6 | 100mg | $1843 | 2021-12-16 | Buy |
PK7242 Maleate Chemical Properties,Uses,Production
Description
The protein p53, often called the ''guardian of the genome,'' is a transcription factor that is activated in response to cellular stress (low oxygen levels, heat shock, DNA damage, etc.) and acts to prevent further proliferation of the stressed cell by promoting cell cycle arrest or apoptosis. Its role as a tumor suppressor is evident by the observation that approximately 50% of human tumors have mutated or non-functional p53. PK7242 is an inducer of reactivation of mutant p53 in cancer cells. In cancer cells carrying the Y220C mutant, PK7242 binds to the p53-Y220C core domain and induces growth inhibition, cell-cycle arrest, and apoptosis.
PK7242 Maleate Preparation Products And Raw materials
Raw materials
Preparation Products
PK7242 Maleate Suppliers
Global( 18)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
| BOC Sciences | 1-631-485-4226; 16314854226 | info@bocsci.com | United States | 14059 | 65 |
| Pharmacodia (Beijing) Co.,Ltd | +86-400-851-9921 | sales@pharmacodia.com | China | 2317 | 55 |
| Shanghai EFE Biological Technology Co., Ltd. | 021-65675885 18964387627 | info@efebio.com | China | 9708 | 58 |
| Lynnchem | 86-(0)29-85992781 17792393971 | info@lynnchem.com | China | 4587 | 58 |
| Novachemistry | 44-20819178-90 02081917890 | info@novachemistry.com | United Kingdom | 4381 | 58 |
| Wuxi KaideRui Pharmaceutical Technology Co., Ltd | 19906241957 | 1557216087@qq.com | China | 1877 | 55 |
| Shanghai Hongye Biotechnology Co. Ltd | 400-9205774 | sales@glpbio.cn | China | 6870 | 58 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Changzhou Furuisi Biotechnology Co., Ltd | 0519-85524369 | 3477467573@qq.com | China | 8618 | 58 |
PK7242 Maleate
2-(4-(4-fluorophenyl)-3-(1H-pyrrol-1-yl)-1H-pyrazol-1-yl)-N,N-dimethylethanamine
2-[4-(4-fluorophenyl)-3-pyrrol-1-ylpyrazol-1-yl]-N,N-dimethylethanamine
1H-Pyrazole-1-ethanamine, 4-(4-fluorophenyl)-N,N-dimethyl-3-(1H-pyrrol-1-yl)-
2-[4-(4-Fluorophenyl)-3-(1-pyrrolyl)-1-pyrazolyl]-N,N-dimethylethanamine
1446352-68-6
C21H23FN4O4