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CFI-401870

CFI-401870 Structure
CFI-401870 structure
CAS No.
1430741-35-7
Chemical Name:
CFI-401870
Synonyms
CFI401870;CFI-401870;1H-Indazole-5-carboxamide, N-[(R)-cyclopropyl-2-pyridinylmethyl]-3-[4-[(3-endo)-3-hydroxy-8-azabicyclo[3.2.1]oct-8-yl]phenyl]-
CBNumber:
CB73118668
Molecular Formula:
C30H31N5O2
Molecular Weight:
493.6
MDL Number:
MOL File:
1430741-35-7.mol
Last updated:2024-10-23 13:36:13
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CFI-401870 Properties

Boiling point 820.2±65.0 °C(Predicted)
Density 1.345±0.06 g/cm3(Predicted)
pka 13.13±0.46(Predicted)

CFI-401870 Chemical Properties,Uses,Production

Description

CFI-401870 is a orally bioavailable, potent tyrosine threonine kinase (TTK) Inhibitor (TTK IC50 < 10 nM, HCT116 GI50 < 0.1 μM). CFI-401870 displayed low off-target activity (>500×), and microsomal stability (T(1/2) > 30 min). CFI-401870 recapitulated the phenotype of TTK RNAi, demonstrated in vivo tumor growth inhibition upon oral dosing, and was selected for preclinical evaluation.

CFI-401870 Preparation Products And Raw materials

Raw materials

Preparation Products

CFI-401870 Suppliers

Global( 7)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc. 		support@targetmol.com United States 38463 58
TargetMol Chemicals Inc. 		+8613564774135 zijue.cai@tsbiochem.com United States 19863 58
ShangHai Biochempartner Co.,Ltd 177-54423994 17754423994 2853530910@QQ.com China 8014 62
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 0571-85361029 synstar518@163.com China 1990 58
Hubei Kele Fine Chemical Co., Ltd 027-59101668 19945030958 2881924765@qq.com China 8140 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24649 58
https://hanhongsci.com/ 021-54306202 18917919676 info@hanhongsci.com China 29977 58
Supplier Advantage
TargetMol Chemicals Inc. 		58
TargetMol Chemicals Inc. 		58
ShangHai Biochempartner Co.,Ltd 62
Hangzhou Synstar pharmaceutical Technology CO.,Ltd 58
Hubei Kele Fine Chemical Co., Ltd 58
TargetMol Chemicals Inc. 58
https://hanhongsci.com/ 58

View Lastest Price from CFI-401870 manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
CFI-401870 pictures 2024-10-24 CFI-401870
1430741-35-7
 US $2500.00-1980.00 / mg 10g TargetMol Chemicals Inc.
  • CFI-401870 pictures
  • CFI-401870
    1430741-35-7
  • US $2500.00-1980.00 / mg
  • TargetMol Chemicals Inc.
CFI401870 CFI-401870 1H-Indazole-5-carboxamide, N-[(R)-cyclopropyl-2-pyridinylmethyl]-3-[4-[(3-endo)-3-hydroxy-8-azabicyclo[3.2.1]oct-8-yl]phenyl]- 1430741-35-7