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CAY10704

CAY10704 Structure
CAY10704 structure
CAS No.
101784-44-5
Chemical Name:
CAY10704
Synonyms
CAY10704;CAY10704,CAY-10704;Antiviral agent 52;1-[bis(4-chlorophenyl)methyl]-4-methyl-piperazine;Piperazine, 1-[bis(4-chlorophenyl)methyl]-4-methyl-
CBNumber:
CB73152587
Molecular Formula:
C18H20Cl2N2
Molecular Weight:
335.27
MDL Number:
MOL File:
101784-44-5.mol
Last updated:2023-07-21 08:27:59
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CAY10704 Properties

storage temp. Store at -20°C
solubility DMF: 20 mg/ml; DMF:PBS(pH7.2) (1:2): 0.3 mg/ml; DMSO: 20 mg/ml; Ethanol: 16 mg/ml

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS02
Signal word  Danger
NFPA 704
3
0 0

CAY10704 price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 19240 CAY10704 ≥98% 101784-44-5 1mg $49 2024-03-01 Buy
Cayman Chemical 19240 CAY10704 ≥98% 101784-44-5 5mg $216 2024-03-01 Buy
Cayman Chemical 19240 CAY10704 ≥98% 101784-44-5 10mg $380 2024-03-01 Buy
AK Scientific 6587CJ 1-(Bis(4-chlorophenyl)methyl)-4-methylpiperazine 101784-44-5 10mg $521 2021-12-16 Buy
Product number Packaging Price Buy
19240 1mg $49 Buy
19240 5mg $216 Buy
19240 10mg $380 Buy
6587CJ 10mg $521 Buy

CAY10704 Chemical Properties,Uses,Production

Description

CAY10704 is a potent inhibitor of hepatitis C virus (HCV) infection (EC50 = 17 nM) that displays low cytotoxicity of virally-infected human hepatoma Huh7.5.1 cells (CC50 = 21.3 μM).1 It displays good pharmacokinetics in mice when delivered intraperitoneally, with preferential liver distribution without significant hepatotoxicity.1 CAY10704 is selective for HCV over dengue virus (EC50 = 4.62 μM).1

References

1. He, S., Xiao, J., Dulcey, A.E., et al. Discovery, optimization, and characterization of novel chlorcyclizine derivatives for the treatment of hepatitis C virus infection J. Med. Chem. 59(3),841-853(2016).

CAY10704 synthesis

109-01-3
782-08-1
101784-44-5
Synthesis of CAY10704 from 1-Methylpiperazine and 1,1'-(chloromethylene)bis[4-chlorobenzene]

CAY10704 Preparation Products And Raw materials

Raw materials

Preparation Products

CAY10704 Suppliers

Global( 10)Suppliers
Supplier Tel Email Country ProdList Advantage
BOC Sciences 16314854226 info@bocsci.com United States 9926 65
TaiChem Taizhou Limited 052386810091 zcwy9518@yeah.net China 3875 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Jinan Jiuli Biotechnology Co. , Ltd. 14768611851 486064515@qq.com China 2277 58
QUALITY CONTROL SOLUTIONS LTD. 13670046396 ORDERS@QCSRM.COM China 18865 58
TargetMol Chemicals Inc. 4008200310 marketing@tsbiochem.com China 24017 58
Shanghai Yifei Biotechnology Co. , Ltd. 021-65675885 18964387627 customer_service@efebio.com China 8739 58
Supplier Advantage
BOC Sciences 65
TaiChem Taizhou Limited 58
Shanghai Hongye Biotechnology Co. Ltd 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 58
Jinan Jiuli Biotechnology Co. , Ltd. 58
QUALITY CONTROL SOLUTIONS LTD. 58
TargetMol Chemicals Inc. 58
Shanghai Yifei Biotechnology Co. , Ltd. 58
CAY10704 Piperazine, 1-[bis(4-chlorophenyl)methyl]-4-methyl- CAY10704,CAY-10704 1-[bis(4-chlorophenyl)methyl]-4-methyl-piperazine Antiviral agent 52 101784-44-5