6-Maleimidocaproic acid-PFP ester
- CAS No.
- 692739-25-6
- Chemical Name:
- 6-Maleimidocaproic acid-PFP ester
- Synonyms
- 6-Maleimidocaproic acid-PFP ester;6-maleimidohexanoic acid pentafluorophenyl ester;Perfluorophenyl 6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoate;1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-, pentafluorophenylester;1H-Pyrrole-1-hexanoic acid, 2,5-dihydro-2,5-dioxo-, 2,3,4,5,6-pentafluorophenyl ester
- CBNumber:
- CB73162818
- Molecular Formula:
- C16H12F5NO4
- Molecular Weight:
- 377.26
- MDL Number:
- MFCD18916982
- MOL File:
- 692739-25-6.mol
- MSDS File:
- SDS
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
6-Maleimidocaproic acid-PFP ester price More Price(6)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | M137953 | 6-Maleimidocaproicacidpentafluorophenylester | 692739-25-6 | 100mg | $530 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | LIN0000110 | 6-MALEIMIDOCAPROIC ACID PFP ESTER 95.00% | 692739-25-6 | 250MG | $776 | 2021-12-16 | Buy |
| BroadPharm | BP-20416 | 6-MaleimidocaproicacidPFPester 96% | 692739-25-6 | 5G | $1700 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | LIN0000110 | 6-MALEIMIDOCAPROIC ACID PFP ESTER 95.00% | 692739-25-6 | 5MG | $508 | 2021-12-16 | Buy |
| Chemenu | CM319431 | Perfluorophenyl6-(2,5-dioxo-2,5-dihydro-1H-pyrrol-1-yl)hexanoate 95% | 692739-25-6 | 250mg | $426 | 2021-12-16 | Buy |
6-Maleimidocaproic acid-PFP ester Chemical Properties,Uses,Production
Description
6-Maleimidocaproic acid PFP ester contains a maleimide and PFP ester end group. Maleimides react with thiol groups within the pH range of 6.5 to 7.5 and form stable thioester bonds. PFP is an activated ester which can react with amine groups to form stable amide bonds.
Uses
6-Maleimidocaproic acid-PFP ester is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
IC 50
Alkyl-Chain
References
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005
6-Maleimidocaproic acid-PFP ester Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32159 | 58 |
| Nextpeptide Inc | +86-0571-81612335 +8613336028439 | sales@nextpeptide.com | China | 19908 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38630 | 58 | |
| Aceschem Inc. | +1-817863-6948 +1-（817）863-6948 | sales@aceschem.com | United States | 19632 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42056 | 58 |
| Aladdin Scientific | tp@aladdinsci.com | United States | 52924 | 58 | |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131957 | 58 |
| Shanghai Raise Chemical Technology Co.,Ltd | 15026594951 | rs@raise-chem.com | China | 3906 | 55 |
| Shanghai XinKai Chemical Technology Co., Ltd. | 021-58930698 15921516558 | zhangyichao84@126.com | China | 951 | 55 |
| ATK CHEMICAL COMPANY LIMITED | 021-51619050 13301662590 | mandy@atkchemical.com | China | 9109 | 55 |
View Lastest Price from 6-Maleimidocaproic acid-PFP ester manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-10-24 | 6-Maleimidocaproic acid-PFP ester
692739-25-6
|
US $0.00 / mg | 10g | TargetMol Chemicals Inc. |
-
- 6-Maleimidocaproic acid-PFP ester
692739-25-6
- US $0.00 / mg
- TargetMol Chemicals Inc.