Chapso
- CAS No.
- 82473-24-3
- Chemical Name:
- Chapso
- Synonyms
- CHAPSO;Hydroxy analog;CHAPSO extrapure;CHAPSO detergent;CHAPSO SIGMAULTRA;CHAPSO,ELECTROPHORESISGRADE;CHAPSO 96% For Biochemistry;CHAPSO Buffer extrapure, 99%;CHAPSO ELECTROPHORESIS REAGENT;CHAPSO - CAS 82473-24-3 - Calbiochem
- CBNumber:
- CB7323821
- Molecular Formula:
- C32H58N2O8S
- Molecular Weight:
- 630.88
- MDL Number:
- MFCD00081079
- MOL File:
- 82473-24-3.mol
- MSDS File:
- SDS
| Melting point | 184-186 °C(lit.) |
|---|---|
| Density | 1.0453 (rough estimate) |
| refractive index | 1.6900 (estimate) |
| storage temp. | -20°C |
| solubility | H2O: 10 mg/mL at 20 °C, clear, colorless |
| form | White solid |
| color | White crystalline |
| Odor | Odorless |
| Water Solubility | 10 g/l at 20 °C |
| Merck | 13,2052 |
| BRN | 5842642 |
| CAS DataBase Reference | 82473-24-3(CAS DataBase Reference) |
| FDA UNII | V9N9RGA14M |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H315-H319-H335 |
| Precautionary statements | P261-P305+P351+P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| WGK Germany | 3 |
| F | 3-10 |
| HS Code | 2924297099 |
Chapso price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 220202 | CHAPSO - CAS 82473-24-3 - Calbiochem Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state. | 82473-24-3 | 1g | $177 | 2024-03-01 | Buy |
| Sigma-Aldrich | 220202 | CHAPSO - CAS 82473-24-3 - Calbiochem Unique detergent with high CMC that solubilizes membrane-bound proteins in their native state. | 82473-24-3 | 5G | $598 | 2024-03-01 | Buy |
| Sigma-Aldrich | C4695 | CHAPSO BioXtra | 82473-24-3 | 500mg | $214 | 2024-03-01 | Buy |
| Sigma-Aldrich | C4695 | CHAPSO BioXtra | 82473-24-3 | 1g | $304 | 2024-03-01 | Buy |
| Sigma-Aldrich | C3649 | CHAPSO ≥98% | 82473-24-3 | 500mg | $122 | 2024-03-01 | Buy |
Chapso Chemical Properties,Uses,Production
Chemical Properties
Chapso is a white crystalline powder. It is a zwitterionic detergent similar to Chaps, however, Chapso is more soluble and particularly better for the solubilization of integral membrane proteins.
Uses
Chapso is a nondenaturing biological detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.
Application
3-(cholamidopropyl)(dimethylammonio)-2-hydroxy-1-propanesulfonate (CHAPSO) may be used in bicelle preparation for β2-adrenergic receptor reconstitution.
CHAPSO has been used:
in a study to assess the processes of liposome solubilization and reconstitution of two transport proteins
in a study to investigate a novel bicelle system for orienting macromolecules over a wide temperature range
as a mixture with dilauroyl phosphatidylcholine (DLPC) in solid-state nuclear magnetic resonance (NMR) technique to study membrane-associated proteins
A nondenaturing zwitterionic detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.
General Description
CHAPSO is a non-denaturing zwitterionic bile salt derivative, derived from Chaps by the addition of a functional hydroxyl group.
Purification Methods
Dissolve this zwitterionic detergent (~ 60g) in 40% aqueous MeOH and stir it with the mixed-bed ion-exchange resin RG-501 x 8 (100g, Bio-Rad) until the pH of the supernatant is ~ 7. Filter off the resin and evaporate the filtrate to dryness under reduced pressure. Check for homogeneity by TLC on silica gel G in 95% MeOH/5% NH4OH and visualize the spot with iodine vapour (see CHAPS above). [Hjelmeland et al. Anal Biochem 130 72 1983, Matuo et al. Methods Enzymol 198 155 1991.]
Chapso Preparation Products And Raw materials
Raw materials
Preparation Products
Chapso Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Yanxi Chemical Co., Ltd. | +8617531190177 | peter@yan-xi.com | China | 5857 | 58 |
| Apeloa production Co.,Limited | +8619933239880 | admin@apcl.com.cn | China | 852 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22963 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49374 | 58 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29811 | 58 |
| Zhengzhou Alfa Chemical Co.,Ltd | +8618530059196 | sale04@alfachem.cn | China | 13503 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32165 | 58 |
| Hubei Xindesheng Material Technology Co., Ltd. | +8618971041571 | vickyzhao@whdschem.com | China | 174 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 22883 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | sales@afinechem.com | China | 15354 | 58 |
View Lastest Price from Chapso manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-11-22 | CHAPSO
82473-24-3
|
US $0.00-0.00 / g | 1g | ≥98.0% | 10kg/month | WUHAN FORTUNA CHEMICAL CO., LTD | |
 |
2024-11-19 | CHAPSO
82473-24-3
|
US $60.00 / mg | 99.98% | 10g | TargetMol Chemicals Inc. | ||
 |
2024-11-19 | CHAPSO
82473-24-3
|
US $0.80 / g | 1g | 99% | 20000 | Apeloa production Co.,Limited |