チャプソ
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- CAS番号.
- 82473-24-3
- 化学名:
- チャプソ
- 别名:
- チャプソ;3-({3-[(4R)-4-[(1R,3aS,3bR,4R,5aS,7R,9aS,9bS,11S,11aR)-4,7,11-トリヒドロキシ-9a,11a-ジメチル-ヘキサデカヒドロ-1H-シクロペンタ[a]フェナントレン-1-イル]ペンタンアミド]プロピル}ジメチルアザニウミル)-2-ヒドロキシプロパン-1-スルホナート;N,N-ジメチル-N-(2-ヒドロキシ-3-スルホナトプロピル)-3-[(3α,7α,12α-トリヒドロキシ-24-オキソ-5β-コラン-24-イル)アミノ]-1-プロパンアミニウム
- 英語名:
- Chapso
- 英語别名:
- CHAPSO;Hydroxy analog;CHAPSO extrapure;CHAPSO detergent;CHAPSO SIGMAULTRA;CHAPSO,ELECTROPHORESISGRADE;CHAPSO 96% For Biochemistry;CHAPSO Buffer extrapure, 99%;CHAPSO ELECTROPHORESIS REAGENT;CHAPSO - CAS 82473-24-3 - Calbiochem
- CBNumber:
- CB7323821
- 化学式:
- C32H58N2O8S
- 分子量:
- 630.88
- MOL File:
- 82473-24-3.mol
- MSDS File:
- SDS
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チャプソ 物理性質
- 融点 :
- 184-186 °C(lit.)
- 比重(密度) :
- 1.0453 (rough estimate)
- 屈折率 :
- 1.6900 (estimate)
- 貯蔵温度 :
- -20°C
- 溶解性:
- H2O: 10mg/mL at20℃ 無色透明
- 外見 :
- 白い固体
- 色:
- 白色結晶
- 臭い (Odor):
- 無臭
- 水溶解度 :
- 20 °C で 10 g/l
- Merck :
- 13,2052
- BRN :
- 5842642
- CAS データベース:
- 82473-24-3(CAS DataBase Reference)
| メーカー |
製品番号 |
製品説明 |
CAS番号 |
包装 |
価格 |
更新時間 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBSS-9798 |
Chapso |
82473-24-3 |
1g |
￥12500 |
2024-03-01 |
購入 |
|
富士フイルム和光純薬株式会社(wako)
|
W01COBSS-9798 |
Chapso |
82473-24-3 |
5g |
￥50000 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
C3649 |
≥98%
CHAPSO ≥98% |
82473-24-3 |
500mg |
￥13600 |
2024-03-01 |
購入 |
|
Sigma-Aldrich Japan
|
850501P |
3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate, powder
CHAPSO 3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate, powder |
82473-24-3 |
1g |
￥37200 |
2024-03-01 |
購入 |
|
ナカライテスク株式会社(Nacalai)
|
07958-54 |
CHAPSOCMC値:8mM ≧96.0%(HPLC)
CHAPSO ≧96.0%(HPLC) |
82473-24-3 |
5G |
￥33000 |
2024-03-01 |
購入 |
チャプソ 化学特性,用途語,生産方法
外観
白色粉末
溶解性
1g/20ml (水)
化学的特性
Chapso is a white crystalline powder. It is a zwitterionic detergent similar to Chaps, however, Chapso is more soluble and particularly better for the solubilization of integral membrane proteins.
使用
Chapso is a nondenaturing biological detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.
主な応用
3-(cholamidopropyl)(dimethylammonio)-2-hydroxy-1-propanesulfonate (CHAPSO) may be used in bicelle preparation for β2-adrenergic receptor reconstitution.
CHAPSO has been used:
in a study to assess the processes of liposome solubilization and reconstitution of two transport proteins
in a study to investigate a novel bicelle system for orienting macromolecules over a wide temperature range
as a mixture with dilauroyl phosphatidylcholine (DLPC) in solid-state nuclear magnetic resonance (NMR) technique to study membrane-associated proteins
A nondenaturing zwitterionic detergent with characteristics similar to CHAPS, although it is more soluble due to a more polar head group. Useful for the solubilization of integral membrane proteins.
一般的な説明
CHAPSO is a non-denaturing zwitterionic bile salt derivative, derived from Chaps by the addition of a functional hydroxyl group.
純化方法
Dissolve this zwitterionic detergent (~ 60g) in 40% aqueous MeOH and stir it with the mixed-bed ion-exchange resin RG-501 x 8 (100g, Bio-Rad) until the pH of the supernatant is ~ 7. Filter off the resin and evaporate the filtrate to dryness under reduced pressure. Check for homogeneity by TLC on silica gel G in 95% MeOH/5% NH4OH and visualize the spot with iodine vapour (see CHAPS above). [Hjelmeland et al. Anal Biochem 130 72 1983, Matuo et al. Methods Enzymol 198 155 1991.]
チャプソ 上流と下流の製品情報
原材料
準備製品
チャプソ 生産企業
Global( 199)Suppliers
82473-24-3(チャプソ)キーワード:
- 82473-24-3
- 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-2-HYDROXY-1-PROPANESULFONATE
- 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-2-HYDROXY-1-PROPANE SULPHONATE
- 1-Propanaminium, 2-hydroxy-N,N-dimethyl-3-sulfo-N-3-(3.alpha.,5.beta.,7.alpha.,12.alpha.)-3,7,12-trihydroxy-24-oxocholan-24-ylaminopropyl-, inner salt
- CHAPSO,ELECTROPHORESISGRADE
- 3-((3-cholamidopropyl)dimethylammonio)-2-hydroxy-
- CHAPSO 3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate
- CHAPSO SIGMAULTRA
- CHAPSO ELECTROPHORESIS REAGENT
- CHAPSO extrapure
- 3-[(3-CHOLAMIDOPROPYL)DIMETHYLAMMONIO]-2-HYDROXY-1-PROPANESULPHONATE (ULTRAPURE)
- 3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulphonate (Ultrapure) >99.0%
- 3-[(3-CholaMidopropyl)diMethylaMMonio]-2-hydroxy-1-propanesulfonate (CHAPSO)
- CHAPSO Vetec(TM) reagent grade, >=98%
- Hydroxy analog
- CHLOROFORM: ISOAMYL ALCOHOL 24:1 BIOTECH
- CHAPSO detergent
- 3-[(3-Cholamidopropyl)dimethylammonio]-2-hydroxy-1-propanesulfonate ISO 9001：2015 REACH
- 3-[(3-Cholami dopropy1) dime thylammonio]-2-hydroxy-1-propanesulfonate
- CHAPSO Buffer extrapure, 99%
- CHAPSO, 3-[(3-Chloamidopropyl)dimethyl- ammonio]-2- hydroxy-1-propanesulfonate
- CHAPSO - CAS 82473-24-3 - Calbiochem
- 3-[dimethyl-[3-[[(4R)-4-[(3R,5S,7R,10S,12S,13R,14S,17R)-3,7,12-trihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]pentanoyl]amino]propyl]azaniumyl]-2-hydroxypropane-1-sulfonate
- CHAPSO
- 3-[(3-cholamine propyl) dimethylamino] -2-hydroxy-1-propanesulfonic acid internal salt
- 3-[(3-Cholylamine propyl)dimethylamino]-2-hydroxy-1-propanesulfonate
- 3-[(3-Cholesterolaminopropyl)dimethylamino]-2-hydroxy-1-propanesulfonic acid
- CHAPSO 96% For Biochemistry
- チャプソ
- 3-({3-[(4R)-4-[(1R,3aS,3bR,4R,5aS,7R,9aS,9bS,11S,11aR)-4,7,11-トリヒドロキシ-9a,11a-ジメチル-ヘキサデカヒドロ-1H-シクロペンタ[a]フェナントレン-1-イル]ペンタンアミド]プロピル}ジメチルアザニウミル)-2-ヒドロキシプロパン-1-スルホナート
- N,N-ジメチル-N-(2-ヒドロキシ-3-スルホナトプロピル)-3-[(3α,7α,12α-トリヒドロキシ-24-オキソ-5β-コラン-24-イル)アミノ]-1-プロパンアミニウム