ChemicalBook >> CAS DataBase List >>LOXO-195
LOXO-195
- CAS No.
- 1350884-56-8
- Chemical Name:
- LOXO-195
- Synonyms
- LOXO-195;LOXO-195(3aR);(6RS)-LOXO-195;LOXO195 R racemic;Selitrectinib Racemate;Selitrectinib(LOXO-195) Racemate;(18bR)-17-Fluoro-1,2,3,11,12,13,14,18b-octahydro-12-methyl-10H-5,7-ethenopyrazolo[3,4-d]pyrido[2,3-k]pyrrolo[2,1-m][1,3,7]triazacyclotridecin-10-one;12H-15,17-Ethenopyrazolo[3,4-d]pyrido[2,3-k]pyrrolo[2,1-m][1,3,7]triazacyclotridecin-12-one, 5-fluoro-1,2,3,3a,8,9,10,11-octahydro-10-methyl-, (3aR)-
- CBNumber:
- CB73311672
- Molecular Formula:
- C20H21FN6O
- Molecular Weight:
- 380.42
- MDL Number:
- MFCD31620755
- MOL File:
- 1350884-56-8.mol
Last updated:2023-05-09 09:30:50
| Density | 1.51±0.1 g/cm3(Predicted) |
|---|---|
| pka | 11.44±0.40(Predicted) |
| FDA UNII | 0J45910S3X |
LOXO-195 Chemical Properties,Uses,Production
Description
LOXO-195 is an orally available, highly potent, and selective TRK kinase inhibitor designed to overcome drug resistance mediated by acquired mutations. Although responses to TRK inhibition can be dramatic and durable; however, eventually emergence of acquired resistance is found to be inevitable.
LOXO-195 Preparation Products And Raw materials
Raw materials
Preparation Products
LOXO-195 Suppliers
Global( 44)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32760 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29825 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10326 | 58 |
| AFINE CHEMICALS LIMITED | +86-0571-85134551 | info@afinechem.com | China | 15395 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131980 | 58 |
| Shanghai Changyu Medical Technology Co. Ltd. | +86-13301875428 | sales@changyuhe.com | China | 298 | 58 |
| Shanghai YuanQi Biotechnology Co., Ltd. | +86-2332782371 +86-18120098618 | sales@adobechem.com | China | 1250 | 50 |
| Guangzhou Zhiya Chemdrugs Co.,Ltd | 18122150900 | sculk28@163.com | China | 646 | 55 |
1350884-56-8(LOXO-195)Related Search:
LOXO-195
LOXO195 R racemic
12H-15,17-Ethenopyrazolo[3,4-d]pyrido[2,3-k]pyrrolo[2,1-m][1,3,7]triazacyclotridecin-12-one, 5-fluoro-1,2,3,3a,8,9,10,11-octahydro-10-methyl-, (3aR)-
Selitrectinib(LOXO-195) Racemate
(6RS)-LOXO-195
Selitrectinib Racemate
(18bR)-17-Fluoro-1,2,3,11,12,13,14,18b-octahydro-12-methyl-10H-5,7-ethenopyrazolo[3,4-d]pyrido[2,3-k]pyrrolo[2,1-m][1,3,7]triazacyclotridecin-10-one
LOXO-195(3aR)
1350884-56-8