ChemicalBook >> CAS DataBase List >>CIL56
CIL56
- CAS No.
- 300802-28-2
- Chemical Name:
- CIL56
- Synonyms
- CA3;CIL56;CA3 NEW;CIL56(CA3);CA3 (CIL-56);YAP1 inhibitor CA3;CIL56, 10 mM in DMSO;CIL56;CIL-56;CIL 56;CA3;CA-3;CA 3;Recombinant Human CA3 Protein, His Tag;Inhibitor,CIL 56,inhibit,Ferroptosis,CIL56,CIL-56
- CBNumber:
- CB73376842
- Molecular Formula:
- C23H27N3O5S2
- Molecular Weight:
- 489.61
- MDL Number:
- MFCD00323348
- MOL File:
- 300802-28-2.mol
Last updated:2025-01-27 09:38:02
| Boiling point | 741.7±70.0 °C(Predicted) |
|---|---|
| Density | 1.51±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMF: 10 mg/ml; DMSO: 10 mg/ml; DMSO:PBS (pH 7.2)(1:9): 0.1 mg/ml; Ethanol: 0.15 mg/ml |
| form | A crystalline solid |
| pka | 10.16±0.20(Predicted) |
| color | White to off-white |
| UNSPSC Code | 12352200 |
| NACRES | NA.77 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS07,GHS08 |
|---|---|
| Signal word | Danger |
| Hazard statements | H301-H315-H319-H335 |
| Precautionary statements | P260-P270-P264-P308+P311-P301+P310+P330-P405-P501 |
CIL56 price More Price(18)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML2647 | CA3 ≥97% (HPLC) | 300802-28-2 | 5mg | $97.7 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML2647 | CA3 ≥97% (HPLC) | 300802-28-2 | 25mg | $395 | 2024-03-01 | Buy |
| Cayman Chemical | 19287 | CIL56 ≥95% | 300802-28-2 | 1mg | $28 | 2024-03-01 | Buy |
| Cayman Chemical | 19287 | CIL56 ≥95% | 300802-28-2 | 5mg | $90 | 2024-03-01 | Buy |
| Cayman Chemical | 19287 | CIL56 ≥95% | 300802-28-2 | 10mg | $152 | 2024-03-01 | Buy |
CIL56 Chemical Properties,Uses,Production
Uses
CIL56 inhibits YAP/Tead transcriptional activity. Has anti-tumour effects on oesophageal adenocarcinoma with therapeutic potential in combination with 5-FU. Involved in ferroptosis, mediated by iron-dependent ROS.
Biological Activity
CA3 is a potent and selective inhibitor of YAP1 (Hippo co-activator Yes-associated protein 1) th at inhibits YAP1 expression and transcriptional activity in esophageal adenocarcinoma (EAC) cell lines. CA3 potently inhibits growth, induces apoptosis in radiation resistant CSC (cancer stem cell) enriched EAC cells. It inhibits tumor growth of in xenograft model with no apparent toxicity.
CIL56 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 68)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32965 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | factory@coreychem.com | China | 29810 | 58 |
| SHANGHAI T&W PHARMACEUTICAL CO., LTD. | +86-021-61551413 +8618813727289 | contact@trustwe.com | China | 5738 | 58 |
| Tianjin Xinshengjiahe Science & Technology Development Co,.Ltd | +86-86-22-87899925 +86-8618522618860 | 18522618860@163.com | China | 694 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 32161 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6391 | 58 |
| Hangzhou MolCore BioPharmatech Co.,Ltd. | +86-057181025280; +8617767106207 | sales@molcore.com | China | 49734 | 58 |
| TargetMol Chemicals Inc. | support@targetmol.com | United States | 38631 | 58 | |
| Shenyang Zhongshen Zekang Biomedical Technology Research Co., Ltd | +86-18341751992 +86-15382112998 | 757984502@qq.com | China | 892 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43340 | 58 |
CIL56
YAP1 inhibitor CA3
7-bis(piperidin-1-ylsulfonyl)fluoren-9-ylidene]hydroxylamine
N-[2;7-BIS(PIPERIDIN-1-YLSULFONYL)FLUOREN-9-YLIDENE]HYDROXYLAMINE;CA3;CIL 56;CIL-56
2,7-Bis-(piperidine-1-sulfonyl)-fluoren-9-one oxime
N-Hydroxy-2,7-bis(1-piperidinylsulfonyl)-9H-fluoren-9-imine
CA3 NEW
CIL56(CA3)
CIL56;CIL-56;CIL 56;CA3;CA-3;CA 3
9H-Fluoren-9-one, 2,7-bis(1-piperidinylsulfonyl)-, oxime
Recombinant Human CA3 Protein, His Tag
CA3 (CIL-56)
CA3
2,7-Bis(1-piperidinylsulfonyl)-9H-fluoren-9-one oxime
2,7-Bis(piperidin-1-ylsulfonyl)-9H-fluoren-9-one oxime
Inhibitor,CIL 56,inhibit,Ferroptosis,CIL56,CIL-56
CIL56, 10 mM in DMSO
300802-28-2