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MILBEMECTIN A4

CAS No.
51596-11-3
Chemical Name:
MILBEMECTIN A4
Synonyms
Milbemycin EP Impurity A;Milbemycin α3;milbemycin A4;milbemycinb-1;MILBEMECTIN A4;milbemectine a4;Antibiotic B-41A4;Milbemycin oxime A4;Milbemycin EP Imp A;B 41A4, MilbeMycin alpha3
CBNumber:
CB7359655
Molecular Formula:
C32H46O7
Molecular Weight:
542.7
MDL Number:
MFCD04972570
MOL File:
51596-11-3.mol
Last updated:2024-07-02 08:55:16

MILBEMECTIN A4 Properties

Melting point 212-215°
alpha D20 +106° (c = 0.25 in acetone)
Boiling point 732.9±60.0 °C(Predicted)
Density 1.20±0.1 g/cm3(Predicted)
storage temp. 0-6°C
solubility DMF: soluble; DMSO: soluble; Ethanol: soluble; Methanol: soluble
form A solid
pka 12.46±0.70(Predicted)
color White to off-white
FDA UNII 9BSH89E55Y
EPA Substance Registry System Milbemycin A4 (51596-11-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS08
Signal word  Danger
Hazard statements  H350
Precautionary statements  P201-P202-P280-P308+P313-P405-P501
RIDADR  2588
HazardClass  6.1(b)
PackingGroup  III

MILBEMECTIN A4 price More Price(6)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 17155 Milbemycin A4 ≥95% 51596-11-3 1mg $425 2024-03-01 Buy
Cayman Chemical 17155 Milbemycin A4 ≥95% 51596-11-3 5mg $1164 2024-03-01 Buy
AK Scientific 4513CR MilbemycinA4 51596-11-3 5mg $1358 2021-12-16 Buy
American Custom Chemicals Corporation API0016454 MILBEMYCIN ALPHA4 95.00% 51596-11-3 5MG $502.96 2021-12-16 Buy
AK Scientific 4513CR MilbemycinA4 51596-11-3 1mg $557 2021-12-16 Buy
Product number Packaging Price Buy
17155 1mg $425 Buy
17155 5mg $1164 Buy
4513CR 5mg $1358 Buy
API0016454 5MG $502.96 Buy
4513CR 1mg $557 Buy

MILBEMECTIN A4 Chemical Properties,Uses,Production

Description

Milbemycin A4 is the prominent member of a complex family of macrocyclic lactones that contain a characteristic spiroketal group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus. As a compound that potentiates glutamate and GABA-gated chloride-channel opening, milbemycin 4 is used as a nematocide and insecticide.

Uses

Milbemycin A4 is a macrolide compound that is a member of a complex family of macrocyclic lactones that contain structural group produced from the fermentation of soil bacterium S. hygroscopicus subsp. aureolacrimosus. Antibacterial and insecticide (1,2). It potentiates glutamate and GABA-gated chloride-channel opening. Used in the synthesis of Milbemycin A17 (3).

Uses

Milbemycins are a complex family of macrocyclic lactones containing a highly characteristic spiroketal group, produced by Streptomyces hydroscopicus subsp. aureolarcrimosus. Milbemycin A4 is the dominant member of a group of analogues containing a 25-ethyl substituent. Milbemycin A4 is a highly selective and potent nematocide and insecticide. Like the closely related avermectins, milbemycins are thought to act on chloride-gated ion channels.

Uses

Acaricide.

Definition

ChEBI: Milbemycin A4 is a milbemycin.

160081-46-9
51596-11-3
Synthesis of MILBEMECTIN A4 from Milbemycin B, 5-O-demethyl-28-deoxy-6,28-epoxy-25-ethyl-, (2S,6R,25R)- (9CI)

MILBEMECTIN A4 Preparation Products And Raw materials

MILBEMECTIN A4 Suppliers

Global( 67)Suppliers
Supplier Tel Email Country ProdList Advantage
Standardpharm Co. Ltd.
86-714-3992388 overseasales1@yongstandards.com United States 14332 58
Shanghai Longyu Biotechnology Co., Ltd.
+8619521488211 info@longyupharma.com China 2541 58
BOC Sciences
16314854226; +16314854226 inquiry@bocsci.com United States 19741 58
Alfa Chemistry
Info@alfa-chemistry.com United States 24072 58
China National Standard Pharmaceutical Corporation Limited
+8615391658522 overseasales@yongstandards.com China 11922 58
Wuhan Topule Biopharmaceutical Co., Ltd
+8618327326525 masar@topule.com China 8467 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52925 58
QUALITY CONTROL SOLUTIONS LTD.
0755-66853366; 13670046396 ORDERS@QCSRM.COM China 24326 58
Huzhou fuhe Rui biological medicine co., ltd 13626726938 953022190@qq.com China 791 58
SHANG HAI WEI LING BIOTECHNOLOGY CO.,LTD 13917490980 81939905@qq.com China 367 58
milbemycinb-1 MILBEMECTIN A4 milbemectine a4 milbemycin A4 (25R)-25-Ethyl-5β-hydroxy-5-demethoxy-28-O,6β-cyclomilbemycin B (6R,25R)-5-O-Demethyl-28-deoxy-6,28-epoxy-25-ethylmilbemycin B Antibiotic B-41A4 Milbemycin α3 B 41A4, MilbeMycin alpha3 VOZIAWLUULBIPN-WMKNSKLVSA-N Milbemycin Impurity 1(Milbemycin EP Impurity A) Milbemycin oxime A4 Milbemycin EP Imp A Milbemycin B, 5-O-demethyl-28-deoxy-6,28-epoxy-25-ethyl-, (6R,25R)- Milbemycin EP Impurity A (1R,4S,5'S,6R,6'R,8R,10E,13R,14E,16E,20R,21R,24S)-6'-ethyl-21,24-dihydroxy-5',11,13,22-tetramethylspiro[3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6,2'-oxane]-2-one Milbemycin Oxime Impurity 1(Milbemycin Oxime EP Impurity A) 51596-11-3 C32H46O7