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4-(pyridine-2-yl) pyrimidin-2-amine

4-(pyridine-2-yl) pyrimidin-2-amine Structure
4-(pyridine-2-yl) pyrimidin-2-amine structure
CAS No.
66521-65-1
Chemical Name:
4-(pyridine-2-yl) pyrimidin-2-amine
Synonyms
BUTTPARK 41\09-82;Nilotinib Impurity 9(N-Oxide);Nilotinib 2-Pyridinyl Impurity;2-Amino-4-(2-pyridyl)pyrimidine;4-(2-PYRIDINYL)-2-PYRIMIDINAMINE;4-(PYRIDIN-2-YL)PYRIMIDIN-2-AMINE;2-Pyrimidinamine, 4-(2-pyridinyl)-;4-(2-pyridinyl)-2-pyrimidinylamine;2-amino-4-(2-pyridinyl)-pyrimidine;4-(pyridine-2-yl) pyrimidin-2-amine
CBNumber:
CB7364224
Molecular Formula:
C9H8N4
Molecular Weight:
172.19
MDL Number:
MFCD00138711
MOL File:
66521-65-1.mol
Last updated:2023-04-23 13:52:06
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4-(pyridine-2-yl) pyrimidin-2-amine Properties

Melting point 137-139°C
Boiling point 426.5±37.0 °C(Predicted)
Density 1.259±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
pka 3.34±0.10(Predicted)
form Solid
color Off-White to Pale Yellow

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P305+P351+P338
Hazard Codes  Xn
Risk Statements  22
HazardClass  IRRITANT
HS Code  2933599590

4-(pyridine-2-yl) pyrimidin-2-amine price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC P991695 4-(2-Pyridinyl)-2-pyrimidinamine 66521-65-1 50mg $80 2021-12-16 Buy
TRC P991695 4-(2-Pyridinyl)-2-pyrimidinamine 66521-65-1 100mg $120 2021-12-16 Buy
TRC P991695 4-(2-Pyridinyl)-2-pyrimidinamine 66521-65-1 250mg $275 2021-12-16 Buy
Matrix Scientific 042500 4-(2-Pyridinyl)-2-pyrimidinamine >95% 66521-65-1 1g $288 2021-12-16 Buy
AK Scientific 0219AC 4-(Pyridin-2-yl)pyrimidin-2-amine 66521-65-1 1g $381 2021-12-16 Buy
Product number Packaging Price Buy
P991695 50mg $80 Buy
P991695 100mg $120 Buy
P991695 250mg $275 Buy
042500 1g $288 Buy
0219AC 1g $381 Buy

4-(pyridine-2-yl) pyrimidin-2-amine Chemical Properties,Uses,Production

Chemical Properties

Off-White Solid

Uses

Intermediate in the preparation of Nilotinib.

Preparation

Synthesis of 4-(pyridine-2-yl) pyrimidin-2-amine (P2P). (0.5 g, 2.84 mmol) of (Z)-3- dimethylamino-1-(pyridine-2-yl)prop-2-en-1-one was suspended was suspended in 15ml of nbutanol. To the solution (0.346 g, 2.84 mmol) of guanidine nitrate added and followed by the addition of NaOH(0.114 g, 2.84 mmol) and reflux this mixture at 110℃ for 12h. After completion of the reaction the mixture was filtered, the clear yellow solution of filtrate kept for room temperature. After 20 min yellow crystal formed and dried in a vacuum under reduced pressure. Yield (0.296 g, 60%) IR (KBr): 3471, 3142, 1622, 1568, 1463, 1340, 1215, 1095, 993, 783, 650, 524.1H NMR (300 MHz, CDCl3) δ 8.69 (dd, J = 11.9, 10.0 Hz, 1H), 8.45 (dd, J = 5.1, 2.6 Hz, 1H), 8.40 – 8.20 (m, 1H), 7.85 (ddd, J = 17.9, 9.4, 7.3 Hz, 1H), 7.64 (dd, J = 5.1, 2.8 Hz, 1H), 7.53 – 7.30 (m, 1H), 5.30 (s, 2H). 13C NMR (75 MHz, CDCl3) δ 164.49 (s), 163.75 (s), 159.65 (s), 154.75 (s), 149.79 (s), 137.29 (s), 125.41 (s), 121.87 (s), 108.26 (s).

4-(pyridine-2-yl) pyrimidin-2-amine Preparation Products And Raw materials

Raw materials

Preparation Products

4-(pyridine-2-yl) pyrimidin-2-amine Suppliers

Global( 56)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd. 		18871490254 linda@hubeijusheng.com CHINA 28172 58
Standardpharm Co. Ltd. 		86-714-3992388 overseasales1@yongstandards.com United States 14332 58
Alchem Pharmtech,Inc. 		8485655694 sales@alchempharmtech.com United States 63687 58
Career Henan Chemica Co 		+86-0371-86658258 +8613203830695 laboratory@coreychem.com China 30233 58
Dideu Industries Group Limited 		+86-29-89586680 +86-15129568250 1026@dideu.com China 22787 58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		+86-057181025280; +8617767106207 sales@molcore.com China 49734 58
China National Standard Pharmaceutical Corporation Limited 		+8615391658522 overseasales@yongstandards.com China 11922 58
Amadis Chemical Company Limited 		571-89925085 sales@amadischem.com China 131957 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 94657 76
Chemsky（shanghai）International Co.,Ltd. 021-50135380 shchemsky@sina.com China 32321 50
Supplier Advantage
Hubei Jusheng Technology Co.,Ltd. 		58
Standardpharm Co. Ltd. 		58
Alchem Pharmtech,Inc. 		58
Career Henan Chemica Co 		58
Dideu Industries Group Limited 		58
Hangzhou MolCore BioPharmatech Co.,Ltd. 		58
China National Standard Pharmaceutical Corporation Limited 		58
Amadis Chemical Company Limited 		58
J & K SCIENTIFIC LTD. 76
Chemsky（shanghai）International Co.,Ltd. 50

View Lastest Price from 4-(pyridine-2-yl) pyrimidin-2-amine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-(2-PYRIDINYL)-2-PYRIMIDINAMINE pictures 2022-02-11 4-(2-PYRIDINYL)-2-PYRIMIDINAMINE
66521-65-1
 US $1.10 / g 1g 99.00% 100 Tons Dideu Industries Group Limited

66521-65-1(4-(pyridine-2-yl) pyrimidin-2-amine)Related Search:

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4-(2-PYRIDINYL)-2-PYRIMIDINAMINE 4-(PYRIDIN-2-YL)PYRIMIDIN-2-AMINE BUTTPARK 41\09-82 4-(2-pyridinyl)-2-pyrimidinylamine 4-(2-pyridinyl)-2-pyrimidinamine (en) 2-amino-4-(2-pyridinyl)-pyrimidine Nilotinib 2-Pyridinyl Impurity Nilotinib Impurity 9(N-Oxide) 2-Amino-4-(2-pyridyl)pyrimidine 2-Pyrimidinamine, 4-(2-pyridinyl)- 4-(2-PYRIDINYL)-2-PYRIMIDINAMINE ISO 9001：2015 REACH 4-(pyridine-2-yl) pyrimidin-2-amine 66521-65-1 Aromatics Heterocycles Intermediates & Fine Chemicals Pharmaceuticals