ChemicalBook >> CAS DataBase List >>(ACETYLMETHYLENE)TRIPHENYLPHOSPHORANE
(ACETYLMETHYLENE)TRIPHENYLPHOSPHORANE
- CAS No.
- 1439-36-7
- Chemical Name:
- (ACETYLMETHYLENE)TRIPHENYLPHOSPHORANE
- Synonyms
- 1-(TRIPHENYLPHOSPHORANYLIDENE)-2-PROPANONE;(2-Oxopropylidene)triphenylphosphorane;NSC 407394;1-(TriphenyL;phosphoranyL;AURORA KA-1177;idene)-2-propanone;Triphenyl(acetylMethylene)phospho;(Acetonylidene)triphenylphosphorane;(Triphenylphosphoranylidene)acetone
- CBNumber:
- CB7371857
- Molecular Formula:
- C21H19OP
- Molecular Weight:
- 318.35
- MDL Number:
- MFCD00008774
- MOL File:
- 1439-36-7.mol
- MSDS File:
- SDS
Last updated:2025-01-27 09:38:02
| Melting point | 203-205 °C (lit.) |
|---|---|
| Boiling point | 478.5±28.0 °C(Predicted) |
| Density | 1.14 |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Soluble in chloroform. Slightly soluble in methanol. |
| form | Powder |
| color | White to off-white |
| Sensitive | Air Sensitive |
| BRN | 750077 |
| Stability | Stable. Combustible. Incompatible with strong oxidizing agents. |
| CAS DataBase Reference | 1439-36-7(CAS DataBase Reference) |
| UNSPSC Code | 12352115 |
| NACRES | NA.22 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P305+P351+P338 | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | UC3900000 | |||||||||
| HS Code | 29319090 | |||||||||
| NFPA 704 |
|
(ACETYLMETHYLENE)TRIPHENYLPHOSPHORANE price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 158755 | 1-(Triphenylphosphoranylidene)-2-propanone 99% | 1439-36-7 | 25g | $197 | 2024-03-01 | Buy |
| Sigma-Aldrich | 158755 | 1-(Triphenylphosphoranylidene)-2-propanone 99% | 1439-36-7 | 100g | $444.6 | 2024-03-01 | Buy |
| TCI Chemical | A1439 | (Acetylmethylene)triphenylphosphorane >98.0%(GC) | 1439-36-7 | 25g | $89 | 2024-03-01 | Buy |
| Alfa Aesar | A11410 | (Acetylmethylene)triphenylphosphorane, 99% | 1439-36-7 | 10g | $45.65 | 2024-03-01 | Buy |
| Alfa Aesar | A11410 | (Acetylmethylene)triphenylphosphorane, 99% | 1439-36-7 | 50g | $153.65 | 2024-03-01 | Buy |
(ACETYLMETHYLENE)TRIPHENYLPHOSPHORANE Chemical Properties,Uses,Production
Chemical Properties
white to light beige crystalline powder
Uses
(Acetylmethylene)triphenylphosphorane is used as a Wittig reagent in synthetic chemistry, especially for the synthesis of functionalized pyrrolidines and cyclobutanones. It plays as a vital role in asymmetric allylboration for enantioselective synthesis of (+)-awajanomycin.It is also employed as a reactant in the preparation of 1,2-dioxanes with antitrypanosomal activity. Further, it is used in the preparation of amphibian pyrrolizidine alkaloids through allylic aminations and silicon-containing acyclic dienone musk odorants. In addition to this, it is involved in Domino Suzuki/Heck coupling reactions to prepare fluorenylidenes.
reaction suitability
reaction type: C-C Bond Formation
Synthesis
The preparative method of (Acetylmethylene)triphenylphosphorane: treatment of Triphenylphosphine with chloro- or Bromoacetone provides the phosphonium salt (eq 1). Deprotonation with a weak base such as bicarbonate in cold water provides the crude ylide which may by isolated by filtration.
storage
Handling, Storage, and Precautions: may be handled in atmosphere for short periods; will decompose in water at pH > 9.
(ACETYLMETHYLENE)TRIPHENYLPHOSPHORANE Preparation Products And Raw materials
Raw materials
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Preparation Products
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Global( 238)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 | sales@frappschem.com | China | 880 | 50 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32965 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 | sales@coreychem.com | China | 29871 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 | info@accelachem.com | United States | 18478 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 | sales@chemdad.com | China | 39894 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 49476 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | +86-29-81139210 +86-18192627656 | 1059@dideu.com | China | 3003 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 | sales@tnjchem.com | China | 34563 | 58 |
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 | mcbio_sales@163.com | China | 2251 | 58 |
View Lastest Price from (ACETYLMETHYLENE)TRIPHENYLPHOSPHORANE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-03-16 | (AcetylMethylene)triphenylphosphorane
1439-36-7
|
US $1.00-0.00 / KG | 1KG | 99% | 20 tons | Shaanxi Dideu Medichem Co. Ltd | |
 |
2019-07-10 | (ACETYLMETHYLENE)TRIPHENYLPHOSPHORANE
1439-36-7
|
US $3.00 / KG | 1KG | 99% | 100kg | Career Henan Chemical Co |
-
- (AcetylMethylene)triphenylphosphorane
1439-36-7
- US $1.00-0.00 / KG
- 99%
- Shaanxi Dideu Medichem Co. Ltd
-
- (ACETYLMETHYLENE)TRIPHENYLPHOSPHORANE
1439-36-7
- US $3.00 / KG
- 99%
- Career Henan Chemical Co
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(METHYLCARBONYLMETHYLENE)TRIPHENYLPHOSPHORANE
(ACETYLMETHYLENE)TRIPHENYLPHOSPHORANE
1-TRIPHENYLPHOSPHANYLIDENE-PROPAN-2-ONE
triphenylphosphoranylidene-2-propanon
AURORA KA-1177
triphenylphosphoranylidene-2-propanone
1-(triphenylphosphoranylidene)acetone
2-Propanone, 1-(triphenylphosphoranylidene)-
(Acetylylmethylene)triphenylphosphorane, 99 %
2-Propanone, triphenylphosphoranylidene.
Triphenyl(2-oxopropylidene)phosphorane
1-Triphenylphosphoranylidene-2-propanone,99%
(Acetonylidene)triphenylphosphorane
Methyl (Triphenylphosphoranylidene)Methyl Ketone
NSC 407394
Triphenyl(acetylMethylene)phospho
1-(Triphenylphosphoranylidene)propan-2-one
ACETYLMETHYLENETRIPHENYLPHOSPHORANE FOR
(Acetylmethylene)triphenylphosphorane, 1-(Triphenylphosphoranylidene)propan-2-one
(Triphenylphosphoranylidene)acetone
(Acetylylmethylene)triphenylphosphorane
1-Triphenylphosphoranylidene-2-propanone, 99% 25GR
Acetyl Methylene triphenylphosphine
1-Triphenylphosphoranylidine-2-propanone
1-(Triphenylphosphoranylidene)-2-propanone 99%
Acetylmethylenetriphenylphosphorane for synthesis
(Triphenylphosphoranylidene)acetone 98%
1-(TriphenyL
idene)-2-propanone
phosphoranyL
(Acetylmethylene)triphenylphosphorane >
1-Triphenylphosphoranylidene-2-propanone, 98%, for synthesis
1-(Triphenylphosphoranyliden)aceton
(2-Oxopropylidene)triphenylphosphorane
1-(TRIPHENYLPHOSPHORANYLIDENE)-2-PROPANONE
1439-36-7
C21H19OP
C21H19PO
CH3COCHPC6H53
Synthetic Reagents
Wittig Reagents
C-C Bond Formation
Wittig & Horner-Emmons Reaction
Wittig Reaction
Olefination
Wittig Reagents
Synthetic Organic Chemistry
Wittig & Horner-Emmons Reaction
Wittig Reaction