1-(트리페닐포스포라닐리덴)-2-프로파논
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1-(트리페닐포스포라닐리덴)-2-프로파논 속성
- 녹는점
- 203-205 °C (lit.)
- 끓는 점
- 478.5±28.0 °C(Predicted)
- 밀도
- 1.14
- 저장 조건
- Inert atmosphere,Room Temperature
- 용해도
- 클로로포름에 용해됩니다. 메탄올에 약간 용해됩니다.
- 물리적 상태
- 가루
- 색상
- 흰색에서 황백색까지
- 감도
- Air Sensitive
- BRN
- 750077
- 안정성
- 안정적인. 타기 쉬운. 강한 산화제와 호환되지 않습니다.
- CAS 데이터베이스
- 1439-36-7(CAS DataBase Reference)
안전
- 위험 및 안전 성명
- 위험 및 사전주의 사항 (GHS)
| 위험 카페고리 넘버 | 22-36/37/38 | ||
|---|---|---|---|
| 안전지침서 | 22-24/25 | ||
| WGK 독일 | 3 | ||
| RTECS 번호 | UC3900000 | ||
| HS 번호 | 29319090 |
1-(트리페닐포스포라닐리덴)-2-프로파논 C화학적 특성, 용도, 생산
화학적 성질
white to light beige crystalline powder용도
(Acetylmethylene)triphenylphosphorane is used as a Wittig reagent in synthetic chemistry, especially for the synthesis of functionalized pyrrolidines and cyclobutanones. It plays as a vital role in asymmetric allylboration for enantioselective synthesis of (+)-awajanomycin.It is also employed as a reactant in the preparation of 1,2-dioxanes with antitrypanosomal activity. Further, it is used in the preparation of amphibian pyrrolizidine alkaloids through allylic aminations and silicon-containing acyclic dienone musk odorants. In addition to this, it is involved in Domino Suzuki/Heck coupling reactions to prepare fluorenylidenes.Synthesis
The preparative method of (Acetylmethylene)triphenylphosphorane: treatment of Triphenylphosphine with chloro- or Bromoacetone provides the phosphonium salt (eq 1). Deprotonation with a weak base such as bicarbonate in cold water provides the crude ylide which may by isolated by filtration.
1-(트리페닐포스포라닐리덴)-2-프로파논 준비 용품 및 원자재
원자재
Phosphonium, (2-oxopropyl)triphenyl-, iodide (1:1)
Phosphonium, methyltriphenyl-, inner salt
(트리메틸실릴메틸)트리페닐포스포늄요오드화물
아세토닐트라이페닐포스포늄 클로라이드
아세토닐트리페닐포스포늄브로마이드
브로모아세톤
준비 용품
1-(트리페닐포스포라닐리덴)-2-프로파논 공급 업체
글로벌( 237)공급 업체
| 공급자 | 전화 | 이메일 | 국가 | 제품 수 | 이점 |
|---|---|---|---|---|---|
| Frapp's ChemicalNFTZ Co., Ltd. | +86 (576) 8169-6106 |
sales@frappschem.com | China | 880 | 50 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 |
ivan@atkchemical.com | China | 32957 | 60 |
| career henan chemical co | +86-0371-86658258 +8613203830695 |
sales@coreychem.com | China | 29880 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 |
linda@hubeijusheng.com | CHINA | 28172 | 58 |
| Accela ChemBio Inc. | +1-858-6993322 |
info@accelachem.com | United States | 17777 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-6139-8061 +86-86-13650506873 |
sales@chemdad.com | China | 39894 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 |
sales@conier.com | China | 49374 | 58 |
| Shaanxi Dideu Medichem Co. Ltd | 18192627656 |
1012@dideu.com | China | 3003 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418671 +8618949823763 |
sales@tnjchem.com | China | 34563 | 58 |
| Xi'an MC Biotech, Co., Ltd. | 029-89275612 +8618991951683 |
mcbio_sales@163.com | China | 2251 | 58 |
1-(트리페닐포스포라닐리덴)-2-프로파논 관련 검색:
(트리페닐포스포라닐리덴)아세트알데히드 트리페닐포스핀 아세톤 1-(트리페닐포스포라닐리덴)-2-프로파논
6-broMo-8-cyclopentyl-5-Methyl-2-(5-(piperazin-1-yl)pyridin-2-ylaMino)pyrido[2,3-d]pyriMidin-7(8H)-one
PalBociclib Impurity 17
PalBociclib Impurity 24
Palbociclib Impurity 15
Pyrido[2,3-d]pyriMidin-7(8H)-one, 2,6-dibroMo-8-cyclopentyl-5-Methyl-
2-chloro-4-(cyclopentylamino)-5-pyrimidinyl ethanone
PalBociclib Impurity 23
Palbociclib-012
PalBociclib Impurity 25
Pyrido[2,3-d]pyriMidin-7(8H)-one, 8-cyclopentyl-5-Methyl-2-[[5-(1-piperazinyl)-2-pyridinyl]aMino]-
PalBociclib Impurity 14
8-cyclopentyl-5-methyl-2-((5-(piperazin-1-yl)pyridin-2-yl)amino)-6-vinylpyrido[2,3-d]pyrimidin-7(8H)-one
tert-Butyl 4-(6-((6-(1-butoxyvinyl)-8-cyclopentyl-5-methyl-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidin-2-yl)amino)pyridin-3-yl)piperazine-1-carboxylate
PalBociclib Impurity 22