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BIOTIN-NHS

BIOTIN-NHS structure

CAS No.: 35013-72-0

Chemical Name:: BIOTIN-NHS

Synonyms: NHS-BIOTIN;BIOTIN-OSU;BNHS;2,5-dioxopyrrolidin-1-yl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]iMidazol-4-yl)pentanoate;(2,5-dioxopyrrolidin-1-yl) 5-[(3aS,4S,6aR)-2-oxo-1,3,3a,4,6,6a-hexahydrothieno[3,4-d]imidazol-4-yl]pentanoate;BHSE;BIOTIN SE;BIOTIN-NHS;D-BIOTIN, SE;NHS-D-BIOTIN

CBNumber:: CB7371998

Molecular Formula:: C14H19N3O5S

Molecular Weight:: 341.38

MDL Number:: MFCD00078531

MOL File:: 35013-72-0.mol

MSDS File:: SDS

Last updated:2025-01-27 09:38:02

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BIOTIN-NHS Properties

Melting point	212-214 °C
Density	1.45±0.1 g/cm3(Predicted)
storage temp.	-20°C
solubility	DMF: ≤50 mg/mL Stable for at least one month in dry DMF
form	powder
pka	13.89±0.40(Predicted)
color	White to off-white
BRN	4720781
Stability	Stable. Incompatible with strong oxidizing agents.
CAS DataBase Reference	35013-72-0(CAS DataBase Reference)
FDA UNII	30M534A3CQ
UNSPSC Code	41116133
NACRES	NA.46

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

EUH210

Precautionary statements

P271-P261-P280

Safety Statements

22-24/25

WGK Germany

10-23

HS Code

2934 99 90

NFPA 704

	1
0		0

BIOTIN-NHS price More Price(79)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	H1759	(+)-Biotin N-hydroxysuccinimide ester ≥98% (HPLC), powder	35013-72-0	5mg	$26.7	2024-03-01	Buy
Sigma-Aldrich	H1759	(+)-Biotin N-hydroxysuccinimide ester ≥98% (HPLC), powder	35013-72-0	1g	$947	2024-03-01	Buy
Sigma-Aldrich	8.51023	Biotin-OSu Novabiochem?	35013-72-0	1g	$254	2024-03-01	Buy
Sigma-Aldrich	203112	Biotin-NHS	35013-72-0	250MG	$401	2024-03-01	Buy
TCI Chemical	S0491	N-Succinimidyl D-Biotinate >97.0%(HPLC)(N)	35013-72-0	100mg	$119	2024-03-01	Buy

Product number	Packaging	Price	Buy
H1759	5mg	$26.7	Buy
H1759	1g	$947	Buy
8.51023	1g	$254	Buy
203112	250MG	$401	Buy
S0491	100mg	$119	Buy

BIOTIN-NHS Chemical Properties,Uses,Production

Description

N-Hydroxysuccinimide (NHS) activates carboxylic acid groups (on biotin) to facilitate coupling reactions. Biotin-NHS is a compound used to attach biotin to primary amines under alkaline conditions (pH~8-9). For example, lysines on the surface of proteins, including antibodies, are ideal targets for biotinylation with this compound.

Chemical Properties

White Solid

Uses

Biotin-NHS is used in the biotinylation of proteins and peptides. Couples with primary amine in the pH range 6.5-8.5.

Uses

amine reactive biotinylation reagent

Uses

Amino reactive biotin reagent for preparing biotinylated surfaces or polypeptides.

reaction suitability

reaction type: Biotinylations

Purification Methods

Recrystallise the ester from refluxing isoPrOH and dry it in a vacuum over P2O5 + KOH. [Jasiewicz et al. Exp Cell Biol 100 213 1976.]

BIOTIN-NHS synthesis

Synthesis of BIOTIN-NHS from N,N'-Disuccinimidyl carbonate and D-Biotin

BIOTIN-NHS Preparation Products And Raw materials

Raw materials

1H-Imidazole, 1-[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]- TSTU D-Biotin

Preparation Products

biotinylamidoethylacetamide LC-LC(+)-Biotin N-BIOTINYL-3,6,9-TRIOXAUNDECANE-1,11-DIAMINE D-BIOTINOL (+)-BIOTIN-EPSILON-AMINOCAPROIC ACID

FMOC-LYS(BIOTIN)-OH 4-((Biotinoyl)amino)Butyric acid N-[6-[[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1 -oxopentyl]amino]hexyl]-carbamic Acid 1,1-Dimethylethyl Ester

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BIOTIN-NHS Suppliers

Global( 411)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Shaanxi Dideu Medichem Co. Ltd	+86-029-81138252 +86-18789408387	1057@dideu.com	China	3922	58
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-+86-371-66670886	info@dakenam.com	China	19805	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21628	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	33024	60
career henan chemical co	+86-0371-86658258 +8613203830695	sales@coreychem.com	China	29858	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	+86 18953170293	sales@sdzschem.com	China	2930	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10406	58
Accela ChemBio Inc.	+1-858-6993322	info@accelachem.com	United States	19825	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63687	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49732	58

Supplier	Advantage
Shaanxi Dideu Medichem Co. Ltd	58
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	58
Shenzhen Nexconn Pharmatechs Ltd	58
Accela ChemBio Inc.	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58

View Lastest Price from BIOTIN-NHS manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-11-19	Biotin NHS 35013-72-0	US $45.00-98.00 / mg		98.63%	10g	TargetMol Chemicals Inc.
2024-11-19	Biotin NHS 35013-72-0	US $45.00-98.00 / mg		98.63%	10g	TargetMol Chemicals Inc.
2024-08-11	BIOTIN-NHS 35013-72-0	US $1.00 / KG	1KG	99%	20T	Shaanxi Dideu Medichem Co. Ltd

Biotin NHS
35013-72-0
US $45.00-98.00 / mg
98.63%
TargetMol Chemicals Inc.

Biotin NHS
35013-72-0
US $45.00-98.00 / mg
98.63%
TargetMol Chemicals Inc.

BIOTIN-NHS
35013-72-0
US $1.00 / KG
99%
Shaanxi Dideu Medichem Co. Ltd

BIOTIN-NHS Spectrum

BIOTIN-NHS(35013-72-0)MS

35013-72-0(BIOTIN-NHS)Related Search:

Sulfo-NHS-Biotin BIOTIN-XX-NHS D-BIOTIN P-NITROPHENYL ESTER Succinimidyl 6-(biotinamido)hexanoate N-Hydroxysuccinimide

methyl 5-[(1S,2S,5R)-7-oxo-3-thia-6,8-diazabicyclo[3.3.0]oct-2-yl]pent anoate BIOTIN HYDRAZIDE (+)-BIOTIN-EPSILON-AMINOCAPROIC ACID BIOTIN DISULFIDE N-HYDROXY-SUCCINIMIDE ESTER Biotin-NHCH2CH2-SS-Pyr

Biotin-SLC-NHS Succinimide BIOTIN-NHS DESTHIOBIOTIN N-HYDROXYSUCCINIMIDYL ESTER 2,5-Dioxopyrrolidin-1-yl octanoate

D-DESTHIOBIOTIN D-biotin-d-sulfoxide 7,8-DIAMINOPELARGONIC ACID

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(+)-biotin-n-hydroxysuccimide ester n-hydroxysuccimidobiotin BIOTIN-OSU: N-HYDROXYSUCCINIMIDOBIOTIN d-Biotin NHS ester 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID 2,5-DIOXO-PYRROLIDIN-1-YL ESTER D-(+)BIOTIN N-HYDROXYSUCCINIMIDE ESTER D-BIOTIN-N-HYDROXYSUCCINIMIDE ESTER D-BIOTIN, SE D-BIOTIN, SUCCINIMIDYL ESTER D-BIOTINYL-OSU BIOTIN-N-HYDROXYSUCCINIMIDE (+)-BIOTIN-N-HYDROXYSUCCINIMIDE ESTER BIOTIN-N-HYDROXYSUCCINIMIDE ESTER BIOTIN-NHS BIOTIN (LONG ARM) NHS BIOTIN SE BIOTIN SUCCINIMIDYL ESTER BIOTINYL-N-HYDROXY-SUCCINIMIDE (+)-BIOTINYL-N-SUCCINIMIDYL ESTER SUCCINIMIDO-(+)-BIOTIN SUCCINIMIDYL D-BIOTIN N-HYDROXYSUCCINIMIDOBIOTIN NHS-D-BIOTIN N-SUCCINIMIDYL D-BIOTINATE N-SUCCINIMIDO-(+)-BIOTIN N-Hydroxysuccinimidyl)biotin (+)-Biotin-NHS Ester 2,5-Dioxopyrrolidin-1-yl 5-((3aS,4S,6aR) 2,5-Dioxopyrrolidin-1-yl 5-((3aS,4S,6aR)-2-oxo-hexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentano Biotin-OSu Novabiochem N-Succinimidyl-D-biotin D-Biotin N-Succinimidyl Ester N-(D-Biotinyloxy)succinimide (+)-Biotin N-succinimidyl ester, d-Biotin NHS ester, Biotinyl-N-hydroxy-succinimide, BNHS, N-Hydroxysuccinimidobiotin, N-Succinimidyl D-biotinate, NHS-Biotin 1-[[5-[(3aS,4S,6aR)-Hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]oxy]-2,5-pyrrolidinedione BHSE (+)-Biotin N-hydroxysuccinimide ester Biotin-NHS N-Hydroxysuccimidobiotin (+)-Biotin N-hydroxysuccinimide ester,(+)-Biotin N-succinimidyl ester, d-Biotin NHS ester, BNHS, Biotinyl-N-hydroxy-succinimide, N-Hydroxysuccinimidobiotin, N-Succinimidyl D-biotinate, NHS-Biotin BIOTIN-NHS (+)-Biotin N-hydroxysucciniMide ester Hexahydro-2-oxo- D-Biotin N-Succinimidyl Ester N-(D-Biotinyloxy)succinimide BNHS, Biotin-NHS BNHS/NHS-Biotin Biotin, succinimidyl ester *CAS 35013-72-0* (+)-Biotin-NHS:BIOTIN-NHS N-Hydroxysuccinimido Biotin、BNHS (+)-Biotin N-hydroxysuccinimide ester(Biotin-NHS) 2,5-Dioxo-1-pyrrolidinyl 5-[(3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl]pentanoate Biotin NHS【2,5-dioxopyrrolidin-1-yl 5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanoate】 CAS_35013-72-0 Biotin-N-succinimidyl N-SuccinimidylD-Biotinate> N-Succinimidyl D-Biotin (Biotin-OSu) 1H-Thieno[3,4-d]imidazole-4-pentanoic acid, hexahydro-2-oxo-, 2,5-dioxo-1-pyrrolidinyl ester, (3aS,4S,6aR)- (+)-Biotin-NHS 2,5-Pyrrolidinedione,1-[[5-[(3aS,4S,6aR)-hexahydro-2-oxo-1H-thieno[3,4-d]imidazol-4-yl]-1-oxopentyl]oxy]- TIANFUCHEM--35013-72-0--BIOTIN-NHS factory price