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MitoPQ

CAS No.
1821370-28-8
Chemical Name:
MitoPQ
Synonyms
MitoPQ;MitoParaquat;MitoPQ (?MitoParaquat);1-Methyl-1'-(10-(triphenylphosphonio)decyl)-[4,4'-bipyridine]-1,1'-diium iodide;1-Methyl-1'-(10-(triphenylphosphonio)decyl)-[4,4'-bipyridine]-1,1'-diium iodide
CBNumber:
CB74666144
Molecular Formula:
C39H46IN2P+2
Molecular Weight:
700.69
MDL Number:
MOL File:
1821370-28-8.mol
Last updated:2024-07-02 08:55:16

MitoPQ Properties

storage temp. Store at -20°C
solubility DMF: 25 mg/ml; DMF:PBS(pH7.2) (1:2): 0.33 mg/ml; DMSO: 1 mg/ml; Ethanol: 0.33 mg/ml
form A crystalline solid
color Brown to reddish brown

MitoPQ price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Cayman Chemical 18808 MitoPQ ≥98% 1821370-28-8 5mg $238 2024-03-01 Buy
Cayman Chemical 18808 MitoPQ ≥98% 1821370-28-8 25mg $887 2024-03-01 Buy
AK Scientific 8144EJ MitoPQ 1821370-28-8 5mg $363 2021-12-16 Buy
Product number Packaging Price Buy
18808 5mg $238 Buy
18808 25mg $887 Buy
8144EJ 5mg $363 Buy

MitoPQ Chemical Properties,Uses,Production

Description

MitoPQ, also known as MitoParaquat, is a redox cycler. MitoParaquat (MitoPQ) that comprises a triphenylphosphonium lipophilic cation conjugated to the redox cycler paraquat. MitoPQ accumulates selectively in the mitochondrial matrix driven by the membrane potential. Within the matrix, MitoPQ produces superoxide by redox cycling at the flavin site of complex I, selectively increasing superoxide production within mitochondria. MitoPQ increased mitochondrial superoxide in isolated mitochondria and cells in culture ~a thousand-fold more effectively than untargeted paraquat. MitoPQ was also more toxic than paraquat in the isolated perfused heart and in Drosophila in vivo. MitoPQ enables the selective generation of superoxide within mitochondria and is a useful tool to investigate the many roles of mitochondrial superoxide in pathology and redox signaling in cells and in vivo.

MitoPQ Preparation Products And Raw materials

Raw materials

Preparation Products

MitoPQ Suppliers

Global( 16)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 support@targetmol.com United States 19973 58
Aladdin Scientific
+1-+1(833)-552-7181 sales@aladdinsci.com United States 52927 58
Jiangsu Nanchuang Chemical and Life Health Research Institute Co., Ltd. 15720605021 zhang_lei@jsnchem.com China 1546 58
Shanghai EFE Biological Technology Co., Ltd. 021-65675885 18964387627 info@efebio.com China 9708 58
Shanghai Hongye Biotechnology Co. Ltd 400-9205774 sales@glpbio.cn China 6870 58
ChemeGen(Shanghai) Biotechnology Co.,Ltd. 18818260767 sales@chemegen.com China 11289 58
Shanghai Anya Pharmaceutical Technology Co., LTD 19106202509 3626423147@qq.com China 973 58
MedBioPharmaceutical Technology Inc 021-69568360 18916172912 order@med-bio.cn China 8141 58
Hefei Mokai Pharmaceutical Technology Co., Ltd 18130062233 3362556465@qq.com China 8000 58
Bide Pharmatech Ltd. 400-1647117 15221909166 product02@bidepharm.com China 63720 58
MitoPQ MitoParaquat 1-Methyl-1'-(10-(triphenylphosphonio)decyl)-[4,4'-bipyridine]-1,1'-diium iodide MitoPQ (?MitoParaquat) 1-Methyl-1'-(10-(triphenylphosphonio)decyl)-[4,4'-bipyridine]-1,1'-diium iodide 1821370-28-8