MitoPQ
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- $238 - $887
- Product name: MitoPQ
- CAS: 1821370-28-8
- MF: C39H46IN2P+2
- MW: 700.69
- EINECS:
- MDL Number:
- Synonyms:MitoPQ;MitoParaquat;1-Methyl-1'-(10-(triphenylphosphonio)decyl)-[4,4'-bipyridine]-1,1'-diium iodide;MitoPQ (?MitoParaquat);1-Methyl-1'-(10-(triphenylphosphonio)decyl)-[4,4'-bipyridine]-1,1'-diium iodide
3 prices
Selected condition：
Brand
- AK Scientific
- Cayman Chemical
Package
- 5mg
- 25mg
- ManufacturerAK Scientific
- Product number8144EJ
- Product descriptionMitoPQ
- Packaging5mg
- Price$363
- Updated2021-12-16
- Buy
- ManufacturerCayman Chemical
- Product number18808
- Product descriptionMitoPQ ≥98%
- Packaging5mg
- Price$238
- Updated2024-03-01
- Buy
- ManufacturerCayman Chemical
- Product number18808
- Product descriptionMitoPQ ≥98%
- Packaging25mg
- Price$887
- Updated2024-03-01
- Buy
| Manufacturer | Product number | Product description | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|
| AK Scientific | 8144EJ | MitoPQ | 5mg | $363 | 2021-12-16 | Buy |
| Cayman Chemical | 18808 | MitoPQ ≥98% | 5mg | $238 | 2024-03-01 | Buy |
| Cayman Chemical | 18808 | MitoPQ ≥98% | 25mg | $887 | 2024-03-01 | Buy |
Properties
storage temp. :Store at -20°C
solubility :DMF: 25 mg/ml; DMF:PBS(pH7.2) (1:2): 0.33 mg/ml; DMSO: 1 mg/ml; Ethanol: 0.33 mg/ml
form :A crystalline solid
color :Brown to reddish brown
solubility :DMF: 25 mg/ml; DMF:PBS(pH7.2) (1:2): 0.33 mg/ml; DMSO: 1 mg/ml; Ethanol: 0.33 mg/ml
form :A crystalline solid
color :Brown to reddish brown
Safety Information
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Description
MitoPQ, also known as MitoParaquat, is a redox cycler. MitoParaquat (MitoPQ) that comprises a triphenylphosphonium lipophilic cation conjugated to the redox cycler paraquat. MitoPQ accumulates selectively in the mitochondrial matrix driven by the membrane potential. Within the matrix, MitoPQ produces superoxide by redox cycling at the flavin site of complex I, selectively increasing superoxide production within mitochondria. MitoPQ increased mitochondrial superoxide in isolated mitochondria and cells in culture ~a thousand-fold more effectively than untargeted paraquat. MitoPQ was also more toxic than paraquat in the isolated perfused heart and in Drosophila in vivo. MitoPQ enables the selective generation of superoxide within mitochondria and is a useful tool to investigate the many roles of mitochondrial superoxide in pathology and redox signaling in cells and in vivo.Suppliers and manufacturers
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