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TH1020

TH1020 structure

CAS No.: 1841460-82-9

Chemical Name:: TH1020

Synonyms: TH1020;TH1020 >=95% (HPLC);4-[[4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-pyrido[3',2';4-[[4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-pyrido[3',2';4-((4-Benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine;4-((4-Benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine;4-[[4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-pyrido[3',2':4,5]thieno[3,2-d]pyrimidine;Pyrido[3',2':4,5]thieno[3,2-d]pyrimidine, 4-[[4-(phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-;interaction,inhibit,Bacterial,flagellin,TH-1020,TH1020,Toll-like Receptor (TLR),TLR5,protein-protein,TNF-α,Inhibitor,TH 1020;6-{[4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-8-thia-3,5,10-triazatricyclo[7.4.0.02,?]trideca-1(9),2(7),3,5,10,12-hexaene

CBNumber:: CB74670635

Molecular Formula:: C23H15N7S2

Molecular Weight:: 453.54

MDL Number:: MFCD30480930

MOL File:: 1841460-82-9.mol

MSDS File:: SDS

Last updated:2024-11-19 23:02:33

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TH1020 Properties

Boiling point	765.8±70.0 °C(Predicted)
Density	1.51±0.1 g/cm3(Predicted)
storage temp.	2-8°C
solubility	Chloroform: 1 mg/ml
form	powder
pka	1.92±0.10(Predicted)
color	white to beige

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319

Precautionary statements

P264-P280-P302+P352-P305+P351+P338-P332+P313-P337+P313-P362

NFPA 704

	0
2		0

TH1020 price More Price(22)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	SML1741	TH1020 ≥95% (HPLC)	1841460-82-9	5MG	$107	2023-06-20	Buy
Sigma-Aldrich	SML1741	TH1020 ≥95% (HPLC)	1841460-82-9	25MG	$434	2023-06-20	Buy
Tocris	6191	TH1020 ≥98%(HPLC)	1841460-82-9	10	$132	2021-12-16	Buy
Tocris	6191	TH1020 ≥98%(HPLC)	1841460-82-9	50	$552	2021-12-16	Buy
TRC	T430010	TH1020	1841460-82-9	50mg	$525	2021-12-16	Buy

Product number	Packaging	Price	Buy
SML1741	5MG	$107	Buy
SML1741	25MG	$434	Buy
6191	10	$132	Buy
6191	50	$552	Buy
T430010	50mg	$525	Buy

TH1020 Chemical Properties,Uses,Production

Uses

TH 1020 is a toll-like receptor 5 (TLR5)/flagellin complex inhibitor.

Uses

TH1020 has been used to inhibit toll-like receptor 5 (TLR5) in porcine intestinal epithelial monolayer cells and mice.

Biochem/physiol Actions

TH1020 is a non-cytotoxic non-cytotoxic toll-like receptor 5 (TLR5)/flagellin complex inhibitor. TH1020 selectively prevents flagellin-induced TLR5 signaling without affecting ligands-induced activation of TLR2, TLR3, TLR4, TLR7 or TLR8.

storage

Store at +4°C

TH1020 Preparation Products And Raw materials

Raw materials

Preparation Products

TH1020 Suppliers

Global( 32)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32957	60
TargetMol Chemicals Inc.	+1-781-999-5354 +1-00000000000	marketing@targetmol.com	United States	32161	58
TargetMol Chemicals Inc.		support@targetmol.com	United States	38631	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	57505	58
Jingmo (Xiamen) Biotechnology Co., Ltd	13621943973; 13621943973	sales@jamxmpharmatech.com	China	1111	58
BOC Sciences	1-631-485-4226; 16314854226	info@bocsci.com	United States	14055	65
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51456	80
Shanghai Lollane Biological Technology Co.,Ltd.	021-52996696，15000506266 15000506266		China	4566	55
Shanghai Chaolan Chemical Technology Center	021-QQ：65489617 15618227136	Sales@ATKchemical.com	China	7296	58
Beijing Solarbio Science & Tecnology Co., Ltd.	010-50973130 4009686088	3193328036@qq.com	China	29785	68

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Jingmo (Xiamen) Biotechnology Co., Ltd	58
BOC Sciences	65
Sigma-Aldrich	80
Shanghai Lollane Biological Technology Co.,Ltd.	55
Shanghai Chaolan Chemical Technology Center	58
Beijing Solarbio Science & Tecnology Co., Ltd.	68

View Lastest Price from TH1020 manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2024-11-19	TH1020 1841460-82-9	US $39.00-97.00 / mg		99.23%	10g	TargetMol Chemicals Inc.

TH1020
1841460-82-9
US $39.00-97.00 / mg
99.23%
TargetMol Chemicals Inc.

TH1020 4-[[4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-pyrido[3',2':4,5]thieno[3,2-d]pyrimidine 4-[[4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-pyrido[3',2' TH1020 >=95% (HPLC) 4-((4-Benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine interaction,inhibit,Bacterial,flagellin,TH-1020,TH1020,Toll-like Receptor (TLR),TLR5,protein-protein,TNF-α,Inhibitor,TH 1020 Pyrido[3',2':4,5]thieno[3,2-d]pyrimidine, 4-[[4-(phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]- 4-((4-Benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl)thio)pyrido[3',2':4,5]thieno[3,2-d]pyrimidine 6-{[4-benzyl-5-(pyridin-4-yl)-4H-1,2,4-triazol-3-yl]sulfanyl}-8-thia-3,5,10-triazatricyclo[7.4.0.02,?]trideca-1(9),2(7),3,5,10,12-hexaene 4-[[4-(Phenylmethyl)-5-(4-pyridinyl)-4H-1,2,4-triazol-3-yl]thio]-pyrido[3',2' 1841460-82-9